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Dr. David Spiegel: Using Hypnosis to Enhance Health & Performance | Huberman Lab Podcast #60



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Welcome to the Huberman Lab Podcast,
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where we discuss science and science-based tools
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for everyday life.
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I'm Andrew Huberman,
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and I'm a professor of neurobiology and ophthalmology
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at Stanford School of Medicine.
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Today, my guest is Dr. David Spiegel.
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Dr. Spiegel is the Associate Chair
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of Psychiatry and Behavioral Sciences
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at Stanford University School of Medicine.
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He is also the Director of the Stanford Center
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on Stress and Health.
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Dr. Spiegel is both a researcher
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and a clinician, meaning he runs a laboratory
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that studies the brain and the body
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and neural mechanisms of how the brain and body interact.
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And he sees patients as a psychiatrist at Stanford.
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His work is incredibly unique
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in that it bridges mind and body,
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but it also has a particular focus
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on the clinical applications of hypnosis.
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As you'll learn today, hypnosis is a unique brain state
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in which neuroplasticity, the brain's ability to change
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in response to experience, may be heightened.
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And indeed, the use of clinical hypnosis
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by Dr. Spiegel and colleagues has been shown
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to improve symptoms of stress, chronic anxiety,
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chronic pain, and various other illnesses,
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including many psychiatric illnesses
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and even outcomes in cancer.
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Today, we discuss hypnosis in the context
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of what's called self-hypnosis
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to distinguish it from stage hypnosis.
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Many of you are probably familiar with stage hypnosis,
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which is really about a hypnotist getting a person
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to do things they would not otherwise do.
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In contrast, clinical hypnosis and the use of hypnosis
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for the treatment of various ailments of mind and body
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is vastly different.
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It involves getting people to change their brain state
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and to use that brain state as a portal
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to make adjustments in their brain and body
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and other aspects of their biology and psychology
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that benefit them.
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And it's been shown over and over again
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in studies by Dr. Spiegel and colleagues
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that those changes can occur extremely quickly.
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Now, not everybody can be hypnotized as readily as the next.
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And so today we also discuss a simple test developed
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by Dr. Spiegel that can help you determine
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whether or not you have a high, medium, or low degree
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of what we call hypnotizability.
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Dr. Spiegel is truly an expert in this area.
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He has published over 480 journal articles,
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170 book chapters on hypnosis,
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and on things like psychosocial oncology,
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which is the interaction of mind and body
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in the treatment of cancer and cancer outcomes,
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on stress physiology, trauma,
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and other aspects of psychotherapy.
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He's published 13 books.
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So he's truly the world expert in hypnosis
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and clinical applications of hypnosis for mind and body.
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I'm certain that in listening to today's episode,
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you're going to learn a tremendous amount
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about how the brain and body interact,
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about various treatments for all sorts of common ailments
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of mind and body,
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and you're going to get access to tools,
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in particular, a tool that was developed by Dr. Spiegel,
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which is the Reveri app, R-E-V-E-R-I.
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The Reveri app is currently only available for Apple,
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but will soon also be available for Android.
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It does carry a nominal cost,
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but there is a seven-day free trial.
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If you'd like to try it,
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we're providing a link in the show notes.
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The Reveri app is special in that it is based
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on clinical studies and research done
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in the Spiegel lab at Stanford.
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So unlike a lot of hypnosis apps out there
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and resources for hypnosis,
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it was developed with clinical treatments in mind.
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Today, we also discussed the use of breath work,
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and I'm very fortunate that my research lab at Stanford
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has been collaborating very closely with Dr. Spiegel
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in testing and developing specific breath work protocols
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to adjust mind and body for things like anxiety,
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improving mood, and improving sleep.
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Based on his incredible and unique expertise
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and the clarity with which Dr. Spiegel
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communicates information,
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I anticipate that you will really enjoy today's episode
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and that you'll come away from it
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with a lot of actionable tools.
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Some of you might be curious what a clinical hypnosis
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session looks like.
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And for that reason, we had Dr. Spiegel hypnotize me.
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A clip of that hypnosis session is going to be posted
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to the Huberman Lab Clips channel,
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which is available on YouTube.
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Before we begin, I'd like to emphasize that this podcast
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is separate from my teaching and research roles at Stanford.
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It is, however, part of my desire and effort
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to bring zero cost to consumer information about science
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and science-related tools to the general public.
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In keeping with that theme,
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I'd like to thank the sponsors of today's podcast.
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And now for my discussion with Dr. David Spiegel.
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David, thank you so much for being here.
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Andrew, my pleasure.
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Can you tell us what is hypnosis?
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Hypnosis is a state of highly focused attention.
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It's something like looking through the telephoto lens
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of a camera in consciousness.
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What you see, you see with great detail,
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but devoid of context.
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If you've had the experience of getting so caught up
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in a good movie that you forget you're watching a movie
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and enter the imagined world, you're part of the movie,
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not part of the audience,
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you're experiencing it, you're not evaluating it.
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That's a hypnotic like experience
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that many people have in their everyday lives.
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So is any experience that really draws us in hypnotic
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in that sense?
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Or let me give a different example.
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If I'm watching a sports game
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and I'm really wrapped up in the game,
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but I'm also in touch with how it makes me feel in my body,
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kind of registering the excitement or the anticipation,
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is that a state of hypnosis also?
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Because you mentioned there's kind of a narrowing
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of context, but a kind of losing of the self.
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Or do I have that right?
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Yes, it is true that to the extent that your somatic,
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your body experience is a part of the sport event
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that you're engaged with,
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I'd say that is a self-altering hypnotic experience.
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If your physical reactions are distracting you
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or make you think about something else,
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that's when it's less hypnotic like
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and more just one of a series of experiences.
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Okay.
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So I have to ask,
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how did you get into this business of hypnosis?
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Because I think for most people,
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when they hear hypnosis or they think about hypnosis,
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they think of stage hypnosis.
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I think of somebody with a pendant going back and forth
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or people up on a stage,
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you're behaving abnormally for the entertainment of others.
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How did you get into hypnosis as an interest, as a practice?
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And if you would,
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could you contrast the sort of hypnosis that you do
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in the clinical setting with the sort of hypnosis
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that a stage hypnotist does?
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Sure.
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Well, it is something of a genetic illness in my family.
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Both of my parents were psychiatrists and psychoanalysts
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and they told me I was free to be any kind of psychiatrist
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I wanted to be, so here I am.
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My father was training to be a psychoanalyst in 1943
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and he ran into a Viennese refugee
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who couldn't serve in the army but who had studied hypnosis.
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And actually it would interest you
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doing your ophthalmological research.
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He had a smallpox scar right in the middle of his forehead
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and he did forensic examinations
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and he noticed that some of the prisoners
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would focus on that spot on his forehead
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and then close their eyes and seem to go to sleep
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but they were in some altered state.
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So he got interested in hypnosis.
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He used it forensically.
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His name was Gustav von Aschaffenburg
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and he offered to teach young psychiatrists
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how to use hypnosis when they went off into the war.
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And so he trained my father
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and my father got off the analytic couch
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and the analyst mentioned it to him.
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That's how he found out about it.
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And my father said, did I say something wrong in analysis?
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Why is he talking to me now?
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And he found it very useful in helping soldiers
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who had acute pain when they were wounded
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and helping people with conversion
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post-traumatic stress disorders.
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And when he came back, he went back to his training
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but he still was sort of interested in it.
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And he had his, one of his supervisors
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was Frieda Fromreichmann who was a very famous psychoanalyst
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and he said that he had been told to stop doing hypnosis
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because it would ruin his reputation as an analyst.
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And she said to him, what are you so worried
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about your reputation for?
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You're gonna give a course at the institute in hypnosis
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and I know you're gonna do it because I'm gonna take it.
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So he was teaching Frieda Fromreichmann hypnosis
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and he just kept doing it and after a while
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he discovered that he was getting better results
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with a few sessions of hypnosis
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than he was with daily psychoanalysis with his patients
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and so he switched his practice.
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And so the dinner table conversations
link |
00:13:38.200
were pretty interesting and occasionally
link |
00:13:40.200
when he was making a movie of a patient,
link |
00:13:42.400
I would get to watch that.
link |
00:13:44.240
And so when I went to medical school,
link |
00:13:47.920
I figured I'll take a course.
link |
00:13:49.160
There was Tom Hackett who was a chair of psychiatry
link |
00:13:51.360
at Mass General was teaching it.
link |
00:13:52.680
It was a very interesting course.
link |
00:13:54.760
And the day that converted me was I was doing my rotation
link |
00:13:59.680
at Children's Hospital in Boston
link |
00:14:01.240
and the nurse is telling me,
link |
00:14:02.680
Spiegel, your next patient is an asthmatic
link |
00:14:04.840
in room 437 or something and I'm just following
link |
00:14:07.680
the sound of the wheezes down the hall.
link |
00:14:09.680
I go in the room, this is 16-year-old girl,
link |
00:14:11.720
knuckles white, bolt upright in bed, struggling for breath.
link |
00:14:14.720
You can hear the wheezing.
link |
00:14:16.080
She twice had subcutaneous epinephrine, didn't work.
link |
00:14:18.720
They were thinking about general anesthesia
link |
00:14:20.480
and starting her on steroids.
link |
00:14:22.480
And her mother's there crying.
link |
00:14:25.240
And I said, I don't know what else to do.
link |
00:14:28.080
So I said, you want to learn a breathing exercise?
link |
00:14:30.200
And she nods and I got her hypnotized.
link |
00:14:33.560
And then I realized we hadn't gotten
link |
00:14:34.760
to asthma in the course yet.
link |
00:14:36.000
So I made up something very complex.
link |
00:14:37.880
I said, each breath you take will be a little deeper
link |
00:14:40.600
and a little easier.
link |
00:14:42.080
And within five minutes, she's lying back in bed.
link |
00:14:44.160
Her knuckles aren't white, she's not wheezing.
link |
00:14:45.920
Her mother stopped crying.
link |
00:14:47.600
The nurse ran out of the room.
link |
00:14:49.440
And my intern comes to find me.
link |
00:14:51.200
And I figure he's going to pat me on the back
link |
00:14:53.120
and say, nice job, Spiegel.
link |
00:14:54.920
He said, the nurse has filed a complaint with a nursing
link |
00:14:57.120
supervisor that you violated a Massachusetts law
link |
00:14:59.960
by hypnotizing a minor without parental consent.
link |
00:15:03.800
And I thought, well, that's nice.
link |
00:15:07.440
I doubt there is a law like this.
link |
00:15:09.520
So the intern says, you're going to have
link |
00:15:11.120
to stop doing this with her.
link |
00:15:12.360
And I said, why?
link |
00:15:13.040
He said, it's dangerous.
link |
00:15:14.200
I said, you're going to give her generalized anesthesia
link |
00:15:16.480
and put her on steroids, and talking to her is dangerous?
link |
00:15:19.600
He said, well, you'll have to do it.
link |
00:15:21.100
And I said, I'll tell you what, take me off the case
link |
00:15:23.160
if you want.
link |
00:15:23.720
But I'm not going to tell a patient of mine
link |
00:15:25.480
anything I know is not true.
link |
00:15:27.320
So there was a battle over the weekend about what to do.
link |
00:15:30.360
And the intern, the chief resident, attending,
link |
00:15:33.400
we're all arguing about it.
link |
00:15:35.000
And on Monday, they came back with a radical idea.
link |
00:15:37.960
They said, let's ask the patient.
link |
00:15:40.320
I don't think this has ever been done at Children's Hospital
link |
00:15:42.720
before.
link |
00:15:43.220
And she said, oh, I like this.
link |
00:15:45.040
She'd been hospitalized every month for three months
link |
00:15:47.120
in status asthmaticus.
link |
00:15:48.680
She did have one subsequent hospitalization,
link |
00:15:50.640
but after that, went on to study to be a respiratory therapist.
link |
00:15:54.240
And I thought that anything that can help a patient that much,
link |
00:15:57.000
violate a nonexistent Massachusetts law,
link |
00:15:59.880
frustrate the nursing supervisor,
link |
00:16:01.460
had to be worth looking into.
link |
00:16:02.880
So I just kept doing it.
link |
00:16:04.840
I discovered that all of my classmates in medical school
link |
00:16:08.560
had just read the new issue of the New England Journal
link |
00:16:10.800
and had some new medication to suggest.
link |
00:16:13.240
And surgeons would say, look, if you
link |
00:16:16.000
can help this guy with his pain or his anxiety, anything
link |
00:16:19.200
above the neck, that's yours.
link |
00:16:20.440
Do it, Spiegel.
link |
00:16:21.120
So I was having fun and being able to learn
link |
00:16:25.140
how to help people in a way that just otherwise was not
link |
00:16:28.200
being done.
link |
00:16:28.960
And so it got me thinking about the fact
link |
00:16:32.040
that we're born with this brain, but we don't
link |
00:16:33.960
have a user's manual for it.
link |
00:16:35.360
And we don't use it nearly as well as we can.
link |
00:16:37.680
And that's something your research is all about, too.
link |
00:16:40.520
And so I thought, I want to understand this better,
link |
00:16:44.080
and I want to see what we can do.
link |
00:16:45.800
Stage hypnotists drive me nuts.
link |
00:16:47.800
They make fools out of people.
link |
00:16:50.960
There was one, this is a case my father was involved.
link |
00:16:55.200
He got a call from, he was at Columbia.
link |
00:16:57.000
He got a call, Spiegel, you got to come see this woman.
link |
00:16:59.400
She's in the ER, and she's in some kind of weird upset state
link |
00:17:03.960
that happened.
link |
00:17:05.560
And it turned out she'd been on the show with a stage
link |
00:17:07.840
hypnotist who, and what they do, by the way,
link |
00:17:11.240
is they cycle around.
link |
00:17:12.880
They have, at the beginning of the show,
link |
00:17:14.600
they don't just grab somebody and say, we're doing this.
link |
00:17:17.000
They get a bunch of people up.
link |
00:17:18.400
They do what amounts to hypnotizability testing
link |
00:17:20.800
to see if people, and they get the ones who
link |
00:17:23.120
are the most hypnotizable.
link |
00:17:24.520
So she was the one.
link |
00:17:26.360
And he said, there's now a little bird in your hand,
link |
00:17:30.440
and you're going to play with a bird.
link |
00:17:32.500
And she starts to cry and scream.
link |
00:17:35.560
And he just gets her off the stage because it's
link |
00:17:37.960
very upsetting.
link |
00:17:39.220
And she's wandering around New York City
link |
00:17:40.880
in the middle of the night, dissociated,
link |
00:17:43.640
and brought to Columbia.
link |
00:17:44.780
And that's where my father saw her.
link |
00:17:46.160
She was still in a kind of uncomfortable,
link |
00:17:48.000
trance-like state.
link |
00:17:48.800
And it turned out that she was the trophy
link |
00:17:51.160
wife of a very wealthy guy.
link |
00:17:53.120
And she felt like a bird in a gilded cage.
link |
00:17:56.080
And so to her, that image just triggered
link |
00:17:59.360
all of this sense of dissatisfaction, discomfort,
link |
00:18:03.040
fear about her life.
link |
00:18:04.720
And he was able to get her reoriented and talk
link |
00:18:07.160
with her about what she was going to do with her life.
link |
00:18:09.400
But I don't like stage hypnosis.
link |
00:18:11.280
You're making fools out of people.
link |
00:18:13.280
And you're using the fact.
link |
00:18:14.520
And that's what scares people about hypnosis.
link |
00:18:16.320
They think you're losing control.
link |
00:18:18.160
You're gaining control.
link |
00:18:19.100
Self-hypnosis is a way of enhancing your control
link |
00:18:21.960
over your mind and your body.
link |
00:18:24.100
It can work very well.
link |
00:18:25.680
But because it gives you a kind of cognitive flexibility,
link |
00:18:29.220
you're able to shift sets very easily,
link |
00:18:32.560
to give up judging and evaluating the way you usually
link |
00:18:35.360
do, and see something from a different point of view.
link |
00:18:38.720
That's a great therapeutic opportunity.
link |
00:18:40.920
But if misused, it could be a danger too.
link |
00:18:43.360
And that's what scares people about it.
link |
00:18:45.160
It is that very ability to suspend critical judgment
link |
00:18:48.760
and just have an experience and see what happens.
link |
00:18:51.320
That can be a great therapeutic opportunity.
link |
00:18:53.800
But if somebody is misusing it, it can be a way to harm people.
link |
00:18:56.520
And there are plenty of examples of people
link |
00:19:00.200
having fantasies imposed on them that they
link |
00:19:02.280
come to think are realities.
link |
00:19:03.520
It's not unusual these days.
link |
00:19:05.160
So it's an ability that, if people
link |
00:19:09.040
learn to recognize and understand it,
link |
00:19:11.320
can be a tremendous therapeutic tool.
link |
00:19:14.360
I've been staged hypnotized.
link |
00:19:18.320
And I've been clinically hypnotized many times
link |
00:19:22.320
through a self-hypnosis app we'll talk about later.
link |
00:19:25.840
And then I know we have plans for you to hypnotize me today.
link |
00:19:30.080
You've done it once before.
link |
00:19:31.920
And I'm very hypnotizable, as we both know.
link |
00:19:35.520
We'll talk about how one can gauge their hypnotizability.
link |
00:19:39.320
But the staged hypnosis was interesting.
link |
00:19:42.760
This was in college.
link |
00:19:43.880
They brought someone out to the dormitory.
link |
00:19:45.600
And I recall being one of the people that was selected
link |
00:19:54.360
and engaging in very bizarre behavior.
link |
00:19:57.880
It wasn't thoroughly embarrassing,
link |
00:19:59.320
but it was pretty embarrassing.
link |
00:20:00.880
And then being sent off the stage,
link |
00:20:03.320
and as I was exiting, suddenly screaming something out
link |
00:20:06.960
because he had planted a suggestion of some sort.
link |
00:20:10.320
And then I was told to look in my pocket.
link |
00:20:12.440
And there was like, I think, a torn up dollar bill.
link |
00:20:14.880
There were a bunch of things
link |
00:20:15.840
that I have vague recollection of.
link |
00:20:17.920
But it raises a set of questions
link |
00:20:22.840
that really boil down to, as a biologist,
link |
00:20:27.040
I always think that there's no events in the brain.
link |
00:20:30.400
There are processes.
link |
00:20:32.040
And so hypnosis, we know, has an induction.
link |
00:20:35.120
Then one is hypnotized, I imagine.
link |
00:20:37.160
And then it sounds like this woman
link |
00:20:38.680
and this example of the bird
link |
00:20:41.080
and being distraught in New York City
link |
00:20:44.480
is a failure to exit the hypnotic state.
link |
00:20:47.720
Do we know what sorts of brain areas are active
link |
00:20:51.400
during the induction, the, let's call it the deep hypnosis,
link |
00:20:55.400
and then what's shutting off or changing
link |
00:20:57.680
as people exit hypnosis?
link |
00:20:59.640
Yes, yes, we do.
link |
00:21:00.800
We've studied that.
link |
00:21:01.640
We've been very interested in that.
link |
00:21:02.720
And so we did a study where we selected
link |
00:21:06.720
highly and non-hypnotizable people
link |
00:21:09.600
so we could do the comparison
link |
00:21:11.600
and then hypnotize them in the functional MRI scanner.
link |
00:21:14.960
And we found three things
link |
00:21:17.320
characterize the entry into the hypnotic state.
link |
00:21:20.160
The first is turning down activity
link |
00:21:22.080
in the dorsal anterior cingulate cortex.
link |
00:21:24.120
So the DACC is in the central front middle part
link |
00:21:26.800
of the brain, as you well know.
link |
00:21:28.800
And it's part of what we call the salience network.
link |
00:21:32.360
It's a conflict detector.
link |
00:21:35.200
So if you're engaged in work
link |
00:21:39.000
and you hear a loud noise
link |
00:21:40.040
that you think might be a gunshot,
link |
00:21:41.520
that's your anterior cingulate cortex saying,
link |
00:21:43.600
hey, wait a minute,
link |
00:21:44.480
there's a potential danger over there.
link |
00:21:46.000
You better pay attention to it.
link |
00:21:47.240
So it compares what you're doing
link |
00:21:50.240
with what else is going on
link |
00:21:51.480
and helps you decide what to do.
link |
00:21:53.720
And as you can imagine,
link |
00:21:56.800
turning down activity in that region,
link |
00:21:58.600
make it less likely that you'll be distracted
link |
00:22:00.600
and pulled out of whatever you're in.
link |
00:22:02.800
And in another study,
link |
00:22:04.160
we found that highly hypnotizable people,
link |
00:22:06.000
even without being hypnotized,
link |
00:22:07.960
have more functional connectivity
link |
00:22:10.400
between the DACC, the anterior cingulate cortex,
link |
00:22:13.480
and the left dorsolateral prefrontal cortex,
link |
00:22:17.520
which is part of a key region
link |
00:22:19.320
in the executive control network.
link |
00:22:20.840
So when you're engaging in tasks,
link |
00:22:22.440
you're enacting a plan,
link |
00:22:24.640
you're writing a paper,
link |
00:22:25.520
you're doing whatever you're doing,
link |
00:22:26.440
that's the prefrontal cortex is doing that.
link |
00:22:29.920
And so if that is coordinated,
link |
00:22:31.960
we found more functional connectivity.
link |
00:22:34.640
So when one is up, the other's up,
link |
00:22:37.040
when one is down, the other's down.
link |
00:22:38.520
That coordination implies that the brain is saying,
link |
00:22:41.840
okay, go ahead, I know what you're doing,
link |
00:22:44.200
carry out that plan
link |
00:22:45.200
and don't worry about other possibilities.
link |
00:22:47.600
So two other things happen when people are hypnotized.
link |
00:22:50.520
One is that that DLPFC
link |
00:22:52.360
has higher functional connectivity with the insula.
link |
00:22:55.240
Another part of the salience network,
link |
00:22:57.040
it's a part of the mind-body control system,
link |
00:22:59.920
sensitive to what's happening in the body,
link |
00:23:01.840
it's part of the pain network as well.
link |
00:23:04.160
But it's also a region of the brain
link |
00:23:06.000
where you can control things in your body
link |
00:23:09.080
that you wouldn't think you could.
link |
00:23:10.280
For example, we did a study years ago
link |
00:23:12.680
where we took people who were highly hypnotizable,
link |
00:23:15.840
hypnotized them and told them to,
link |
00:23:18.480
we went on an imaginary culinary tour.
link |
00:23:21.080
So they would eat their favorite foods.
link |
00:23:24.360
And we found that they increased
link |
00:23:25.880
their gastric acid secretion by 87%.
link |
00:23:29.400
So their stomach was acting as though it was about to get,
link |
00:23:32.520
I mean, there was one woman, it was so vivid for her
link |
00:23:34.760
that halfway through she said, let's stop, I'm full.
link |
00:23:37.960
Eating these imaginary foods.
link |
00:23:38.800
Having never eaten an actual food.
link |
00:23:41.080
No. Incredible.
link |
00:23:42.360
And then we got them to relax
link |
00:23:44.560
and think of anything but food or drink.
link |
00:23:46.800
And we got like a 40% decrease in gastric acid secretion.
link |
00:23:51.320
So they could, and that was DLPFC through the insula
link |
00:23:55.240
telling the stomach you're getting food
link |
00:23:56.800
or you're not getting food.
link |
00:23:57.840
And even, we injected them with pentagastrin,
link |
00:24:00.480
which triggers gastric acid release.
link |
00:24:03.000
And even then in the hypnosis condition
link |
00:24:04.880
they had a 19% reduction in gastric acid.
link |
00:24:07.760
So the brain has this amazing ability
link |
00:24:10.160
to control what's going on in the body
link |
00:24:11.600
in ways that we don't think we have ability to control.
link |
00:24:14.400
That's just one example.
link |
00:24:15.880
So that's the DLPFC-insula connection.
link |
00:24:18.440
The third thing that happens,
link |
00:24:19.880
and this relates to what you did on the stage,
link |
00:24:22.960
is you have inverse functional connectivity
link |
00:24:26.520
between the DLPFC and the posterior cingulate cortex.
link |
00:24:30.960
The posterior cingulate is part of the default mode network.
link |
00:24:34.400
It's in the back of the brain.
link |
00:24:36.280
And it's an area whose activity goes down,
link |
00:24:39.360
for example, in meditators.
link |
00:24:41.400
And in meditation you're supposed to be selfless.
link |
00:24:43.680
You're supposed to, the self is an illusion.
link |
00:24:45.280
You're supposed to let it dissolve
link |
00:24:46.440
and just experience things.
link |
00:24:47.880
And when you're doing that, the posterior cingulate
link |
00:24:50.240
is decreasing in activity.
link |
00:24:52.200
The inverse connection is I'm doing something
link |
00:24:55.400
but I'm not thinking about what it means for me.
link |
00:24:57.960
I may not even remember much of it.
link |
00:25:00.000
If I do, I don't care that much about it.
link |
00:25:02.480
And so that is part of the dissociation
link |
00:25:05.680
that occurs with hypnosis.
link |
00:25:06.920
So it's how you put things outside of conscious awareness
link |
00:25:09.880
and don't worry about what it means.
link |
00:25:11.520
It also adds to cognitive flexibility.
link |
00:25:14.360
If you're thinking, well, people like me
link |
00:25:16.560
don't usually do this, that may inhibit you
link |
00:25:19.320
from enacting a new form of psychotherapy, for example,
link |
00:25:23.080
that you've never done before.
link |
00:25:25.120
But if you're having this decreased activity
link |
00:25:28.080
in the part of your brain that reflects on what it means,
link |
00:25:31.160
you're more likely to be cognitively flexible
link |
00:25:33.440
and willing to give it a try.
link |
00:25:34.640
And that's one of the therapeutic advantages
link |
00:25:36.640
of hypnosis as well.
link |
00:25:38.600
Fascinating.
link |
00:25:39.440
And it's really, I'm gonna put,
link |
00:25:41.760
I'm gonna embarrass you here a little bit
link |
00:25:43.680
in the positive sense.
link |
00:25:45.160
Your laboratory is really the one that's pioneered
link |
00:25:47.800
brain imaging of hypnotic states.
link |
00:25:49.720
And it sounds like that's my understanding.
link |
00:25:52.600
Is that correct?
link |
00:25:53.520
Yeah.
link |
00:25:54.360
I mean, there are other people
link |
00:25:55.200
who've done excellent research too,
link |
00:25:56.680
but Pierre Rainville in Montreal and several other people,
link |
00:25:59.880
but we're one of the leading lamps
link |
00:26:01.680
in neuroimaging of hypnosis.
link |
00:26:04.280
I have to ask about attention deficit
link |
00:26:07.160
hyperactivity disorder.
link |
00:26:08.640
I get a lot of questions about this
link |
00:26:11.120
and I think a lot of people just struggle
link |
00:26:12.760
with holding attention nowadays
link |
00:26:15.000
because of interference with phones and devices.
link |
00:26:18.960
And of course there is a lot
link |
00:26:20.640
of clinically legitimate ADHD out there,
link |
00:26:23.080
but the way that you describe the dorsal
link |
00:26:25.600
and the anterior cingulate and the salience network
link |
00:26:27.920
and this conflict detector of am I focusing on something
link |
00:26:32.080
or am I splitting my attention?
link |
00:26:33.520
How distractible am I seems to relate to some extent
link |
00:26:36.440
to activity in the anterior cingulate cortex.
link |
00:26:40.720
Do people with ADHD display disruptions
link |
00:26:44.840
in elements of these networks
link |
00:26:46.480
and has hypnosis ever been used to,
link |
00:26:51.160
or self-hypnosis I should be,
link |
00:26:53.080
to distinguish from stage hypnosis,
link |
00:26:55.000
clinical and self-hypnosis has been used
link |
00:26:56.960
to enhance people's ability to focus and hold attention
link |
00:27:00.720
because that's such a built-in component
link |
00:27:02.800
of the hypnotic state.
link |
00:27:05.160
It's a great question.
link |
00:27:06.360
There's sort of two ways to think about it.
link |
00:27:08.880
In terms of enhancing focus, yes,
link |
00:27:11.040
it has been very helpful in teaching people
link |
00:27:14.520
to just prepare your mind to narrow in
link |
00:27:16.720
and focus on something.
link |
00:27:18.200
And when you're really engaged in reading something
link |
00:27:20.560
or you're writing a, I mean, I'll have that,
link |
00:27:22.400
sometimes I'm thinking, oh, God,
link |
00:27:24.200
I have to do this for another hour.
link |
00:27:25.560
Other times, an hour will go by and I'll think,
link |
00:27:27.880
hey, great, because when you're in the,
link |
00:27:30.040
it feels game-like to you.
link |
00:27:31.680
You're just assembling the parts of the puzzle
link |
00:27:33.960
and putting them together.
link |
00:27:35.680
It's fun.
link |
00:27:36.520
You just get absorbed.
link |
00:27:37.440
For me, that's a hypnotic-like experience.
link |
00:27:39.480
When I'm having trouble, when I'm struggling,
link |
00:27:41.800
sometimes doing things like self-hypnosis can help.
link |
00:27:45.080
I'm not an expert on ADHD.
link |
00:27:47.680
My impression is that you're right
link |
00:27:49.440
that these are people who are constantly distracted
link |
00:27:52.320
and rather rigid.
link |
00:27:53.720
The other part of it is they're easily distractible.
link |
00:27:55.800
They're very upset when they get distracted
link |
00:27:58.360
and they're rather rigid in what they want to attend to
link |
00:28:00.560
and what they can't, I think,
link |
00:28:01.600
as a way of controlling this distractibility, frankly.
link |
00:28:05.880
My guess is that many people with ADHD
link |
00:28:08.400
would not be that hypnotizable,
link |
00:28:09.940
but I haven't studied it.
link |
00:28:11.480
So it's possible that for some people with that disorder,
link |
00:28:17.240
training in self-hypnosis might help,
link |
00:28:18.880
but we'd have to see how hypnotizable they were
link |
00:28:21.160
and take it from there.
link |
00:28:23.120
I want to return to some of the underlying neural networks
link |
00:28:26.120
and the clinical applications,
link |
00:28:28.200
but what sorts of things,
link |
00:28:32.240
aside from the asthma,
link |
00:28:34.880
have you used hypnosis successfully for,
link |
00:28:39.360
or have others used clinical hypnosis for?
link |
00:28:43.220
And are there any particular areas
link |
00:28:45.840
of psychiatric challenges or illnesses,
link |
00:28:49.520
I guess they're called,
link |
00:28:51.020
that are particularly amenable to hypnotic treatment?
link |
00:28:56.380
Yes, there are.
link |
00:28:57.400
Hypnosis is very good as a problem-focused treatment.
link |
00:29:03.280
It's really, it's the oldest Western conception
link |
00:29:05.400
of a psychotherapy,
link |
00:29:06.840
and it can be used for specific problems
link |
00:29:09.080
in a way that's very helpful.
link |
00:29:10.840
We found it very helpful for stress reduction,
link |
00:29:13.420
for helping people deal,
link |
00:29:14.500
we're all dealing with stress these days.
link |
00:29:17.200
And it's helpful,
link |
00:29:18.660
that mind-body connection is very helpful
link |
00:29:20.600
because part of the problem with stress
link |
00:29:23.840
is your perception,
link |
00:29:25.520
you mentioned it earlier in a sort of good sense,
link |
00:29:27.520
you're at a football game or something
link |
00:29:29.400
and you feel the physical reaction.
link |
00:29:32.000
That can be a reinforcing thing.
link |
00:29:33.960
Wow, this is exciting, let's do it.
link |
00:29:35.820
It can also be very distracting.
link |
00:29:37.540
So you're worried about getting COVID
link |
00:29:40.400
or you're worried about some other physical problem you have
link |
00:29:45.160
and you notice it in your body.
link |
00:29:46.840
Your body tenses up, you start to sweat,
link |
00:29:49.560
the sympathetic nervous system goes,
link |
00:29:51.600
your heart rate goes up.
link |
00:29:53.120
And when you notice that,
link |
00:29:54.740
you think, oh God, this is really bad.
link |
00:29:57.040
And then you feel worse.
link |
00:29:58.140
So it's like a snowball rolling downhill
link |
00:30:00.760
and then you feel worse and then your body gets worse.
link |
00:30:03.800
Hypnosis can be very helpful
link |
00:30:05.440
in dissociating somatic reaction from psychological reaction
link |
00:30:09.240
so we teach people to imagine their body floating
link |
00:30:12.380
somewhere safe and comfortable like a bath, a lake,
link |
00:30:14.760
a hot tub or floating in space.
link |
00:30:16.440
And then picture the problem that's stressing them
link |
00:30:20.200
on an imaginary screen with the rule
link |
00:30:21.720
that no matter what you see on the screen,
link |
00:30:23.180
you keep your body comfortable.
link |
00:30:24.760
So at this point, you still can't control the stress
link |
00:30:27.820
but you can control your physical reaction to it.
link |
00:30:30.640
And that starts you feeling more in control.
link |
00:30:33.000
At least there's one thing I can manage.
link |
00:30:34.560
And then you can use it to think through
link |
00:30:36.360
or visualize through one thing you might do
link |
00:30:38.760
about that stressor.
link |
00:30:39.680
So hypnosis is very helpful in controlling mind-body
link |
00:30:43.320
interaction in relation to stress.
link |
00:30:46.380
It's very helpful for people to get to sleep.
link |
00:30:49.520
We're having a lot of fun with that.
link |
00:30:51.760
I'm getting emails from people who said,
link |
00:30:54.200
I haven't slept right in 15 years
link |
00:30:56.000
and now for the first time, I'm listening to your app
link |
00:30:59.660
and I can sleep at night.
link |
00:31:01.480
So it's very helpful.
link |
00:31:02.640
And again, if you wake up in the middle of the night,
link |
00:31:07.440
I tell people, don't look at the clock.
link |
00:31:09.060
That's an arousal cue.
link |
00:31:10.400
You'll just wake up more.
link |
00:31:13.080
But picture whatever you're thinking about
link |
00:31:16.200
or worrying about on that imaginary screen
link |
00:31:18.120
while your body's floating.
link |
00:31:19.060
So watch your own movie, but keep your body floating.
link |
00:31:21.960
And many people can use that to get back to sleep.
link |
00:31:24.660
I've been using the self-hypnosis for sleep
link |
00:31:27.660
for a long time.
link |
00:31:29.400
And now the Reverie app, and we'll talk about
link |
00:31:31.520
our relationship to the Reverie app and its uses.
link |
00:31:33.640
I find it incredibly useful for falling back asleep
link |
00:31:36.620
in the middle of the night.
link |
00:31:38.600
And it raises a question I've found,
link |
00:31:43.320
and I think I understand this correctly,
link |
00:31:45.080
that one can do self-hypnosis during the daytime.
link |
00:31:49.920
And then if there's an issue that comes up later,
link |
00:31:52.200
like so for instance, do self-hypnosis for stress reduction
link |
00:31:55.480
away from the stressful event to prepare one
link |
00:31:58.160
to deal with stress better.
link |
00:31:59.520
Or do a hypnosis for improving the return to sleep.
link |
00:32:03.880
And that can be done when you actually want to go to sleep,
link |
00:32:06.280
but it's kind of a training up of these networks, right?
link |
00:32:09.920
That's right.
link |
00:32:10.800
So is there evidence that these brain networks
link |
00:32:14.240
actually form stronger connections
link |
00:32:17.440
when people do self-hypnosis over time?
link |
00:32:21.000
Well, there's a rule in neurobiology, as you know,
link |
00:32:23.380
that neurons that fire together wire together.
link |
00:32:25.480
Our friend, Carla Schatz.
link |
00:32:26.560
Yes, Carla.
link |
00:32:27.400
Not Donald Hebb, by the way.
link |
00:32:28.640
I keep trying to, there's a widespread myth in the world
link |
00:32:32.560
that is unfortunately all over the internet,
link |
00:32:34.920
which is that the word fire together, wire together
link |
00:32:36.920
was said by the psychologist Donald Hebb.
link |
00:32:39.100
Donald had many important things,
link |
00:32:41.000
but it is the neurobiologist, Carla Schatz.
link |
00:32:44.320
That's exactly right.
link |
00:32:45.400
Yes, is at Stanford, but was also at Berkeley and Harvard.
link |
00:32:48.160
So also decent schools.
link |
00:32:51.240
But is at Stanford who said fire together, wire together.
link |
00:32:55.280
And so she deserves the credit for that statement.
link |
00:32:58.520
Yeah, so with repeated use of self-hypnosis,
link |
00:33:03.040
one could imagine that these networks are getting stronger.
link |
00:33:06.200
I would think so.
link |
00:33:07.720
We don't have evidence of that yet,
link |
00:33:10.080
but long-term potentiation provides a pathway,
link |
00:33:16.240
and you've described them on your program a number of times,
link |
00:33:18.860
that allow for repeated activation of a network
link |
00:33:22.060
to actually build new connections that work.
link |
00:33:25.240
And at the least,
link |
00:33:26.480
even from a learning and memory point of view,
link |
00:33:28.920
our memory is all a network of associations.
link |
00:33:32.640
That's how we remember things.
link |
00:33:34.760
And the example I'd like to give
link |
00:33:36.920
is you go back to your grade school,
link |
00:33:39.240
and you see these little tiny lockers,
link |
00:33:41.520
and the size is all wrong,
link |
00:33:43.360
and you suddenly have a flood of memories
link |
00:33:45.280
that were obviously stored there,
link |
00:33:47.520
but you just didn't think of.
link |
00:33:48.560
So context and association is what memory is about.
link |
00:33:52.360
If you start to acquire memories about a problem,
link |
00:33:55.360
so one thing we use hypnosis for
link |
00:33:57.320
is treating phobias, for example.
link |
00:33:59.160
And the problem with people who have phobias,
link |
00:34:01.100
like airplane phobias, or crossing a bridge,
link |
00:34:04.640
or being up high, is that the more they avoid it,
link |
00:34:08.240
the more the only source of associations and memories
link |
00:34:11.840
is their fear.
link |
00:34:12.920
They don't have any good experiences with it
link |
00:34:14.840
because they avoid it.
link |
00:34:16.240
It's like get back on the horse
link |
00:34:17.400
after you fall off kind of thing.
link |
00:34:19.280
And with hypnosis, if you can start people able
link |
00:34:24.280
to manage their anxiety enough
link |
00:34:26.280
that they can have more, a wider array of experiences,
link |
00:34:29.680
they start to have a network of associations
link |
00:34:32.280
that isn't so negative and may even be positive.
link |
00:34:34.720
So it's almost like a, sorry to interrupt,
link |
00:34:36.800
but I have to ask, it's almost like a exposure therapy
link |
00:34:40.800
done in the mind.
link |
00:34:42.960
I mean, it's always in the mind.
link |
00:34:44.200
I mean, even exposure to, if I have a snake phobia,
link |
00:34:46.760
which I don't, I don't like snakes,
link |
00:34:48.740
but I don't think it qualifies as a full-blown phobia.
link |
00:34:51.280
I think I have a healthy fear of snakes.
link |
00:34:53.800
But if, let's say I had a snake phobia,
link |
00:34:57.640
the typical approach would be cognitive behavioral
link |
00:35:02.440
approaches, right?
link |
00:35:03.280
Would be to show a picture of a snake
link |
00:35:04.800
or then a rubber snake, then a real snake.
link |
00:35:06.280
Eventually the person is holding a boa constrictor
link |
00:35:09.160
or something like that.
link |
00:35:10.960
That's all in the mind because it's all translated
link |
00:35:13.520
into nervous system signals.
link |
00:35:14.720
But with hypnosis, sounds like you can give
link |
00:35:17.280
a number of positive experiences
link |
00:35:19.280
without having to use any props,
link |
00:35:21.480
without having to bring any animals into the room
link |
00:35:23.960
to drive someone across the bridge.
link |
00:35:25.360
Is that right?
link |
00:35:26.200
Yes.
link |
00:35:27.040
I had a woman who was a very successful businesswoman,
link |
00:35:29.760
high level in a corporation.
link |
00:35:31.920
I had a terrible dog phobia.
link |
00:35:33.560
And so I had her imagine that somebody brought in
link |
00:35:37.200
a dog to the room and I said, what are you doing?
link |
00:35:39.280
And you could see her getting tense.
link |
00:35:41.280
And she said, well, I'm waiting to see what the dog does.
link |
00:35:44.320
And I said, if somebody who works for you
link |
00:35:46.520
comes into your office, would you freeze
link |
00:35:48.440
and wait to see what they did?
link |
00:35:50.440
And she said, of course not.
link |
00:35:51.680
And I tell them what to do, you know.
link |
00:35:54.120
And I said, well, so you're immobilizing yourself.
link |
00:35:56.560
The power isn't with the dog, it's with you.
link |
00:35:58.960
So imagine what you might do to engage the dog
link |
00:36:01.720
and help control the situation.
link |
00:36:04.360
And she said, thanks.
link |
00:36:05.360
And this reminds me of one of my favorite stories
link |
00:36:08.320
about hypnosis that my father was seeing a woman
link |
00:36:12.000
who lived in Midtown Manhattan
link |
00:36:13.240
and had a horrible dog phobia.
link |
00:36:14.960
She'd drop things, she'd spill coffee, she saw a dog.
link |
00:36:18.440
She would time her trips to the store
link |
00:36:20.520
when she thought it was least likely
link |
00:36:21.960
that people would be walking dogs.
link |
00:36:23.200
Now that wouldn't be possible.
link |
00:36:24.360
Everyone, it's like a fleet of French bulldogs
link |
00:36:28.440
taking over New York City.
link |
00:36:30.800
So he taught her to think of a dog as a friend,
link |
00:36:35.040
have a neighbor who had a dog, bring the dog over,
link |
00:36:38.840
but hold the dog by the collar and make sure.
link |
00:36:41.400
And gradually she was able to stroke the dog
link |
00:36:44.200
and say, dog friend, and distinguish
link |
00:36:45.680
between wild and tame animals.
link |
00:36:47.120
There are animals, you should be afraid of this.
link |
00:36:49.280
So she seemed to be doing better.
link |
00:36:50.520
He called back about three months later
link |
00:36:53.040
and asked for her and said, well, who's calling?
link |
00:36:56.360
The son said, and he said, Dr. Spiegel.
link |
00:36:58.760
And the boy said, that's weird.
link |
00:37:01.000
And my father said, what's weird?
link |
00:37:02.400
He said, Spiegel's in heat.
link |
00:37:05.200
She had bought a dog and named it Spiegel.
link |
00:37:08.520
Talk about transference.
link |
00:37:09.760
I love it.
link |
00:37:11.160
But it really speaks to the power of this.
link |
00:37:13.480
And it brings me back to this issue.
link |
00:37:18.120
So what is different about what your father did
link |
00:37:22.200
in that case with this woman,
link |
00:37:25.560
in terms of what happened in hypnosis
link |
00:37:29.080
that allowed her to go from being completely terrified
link |
00:37:31.440
of dogs to owning a dog and naming it after your father,
link |
00:37:35.680
which I find amusing.
link |
00:37:37.960
But that's different than just the two of them
link |
00:37:40.600
sitting down and talking about it, right?
link |
00:37:43.120
In therapy, the narrative is a huge component
link |
00:37:47.480
and in hypnosis, narrative is a huge component.
link |
00:37:50.240
So it must be that the brain state
link |
00:37:53.360
is what is really different,
link |
00:37:54.600
because we'll talk about trauma in a few minutes,
link |
00:37:57.360
but I think people who have trauma or phobias
link |
00:38:01.680
certainly could have a conversation about it.
link |
00:38:06.160
Some of them might freeze up.
link |
00:38:07.360
Some of them might lose their articulation and so forth.
link |
00:38:09.960
But what is different about that state
link |
00:38:13.160
that combines with narrative you think
link |
00:38:15.560
to allow these underlying neural networks
link |
00:38:18.160
to engage her to change?
link |
00:38:20.080
Because I find this so fascinating
link |
00:38:21.600
because every attempt at dealing with stress or phobia
link |
00:38:26.720
in the clinical setting involves some discussion
link |
00:38:28.920
about what it is.
link |
00:38:30.360
But here we're not talking about any medication
link |
00:38:33.160
being introduced,
link |
00:38:34.000
at least not in these particular circumstances.
link |
00:38:36.160
So I just, I realized it's kind of an obvious question
link |
00:38:39.880
like it has to be some difference in brain activity,
link |
00:38:42.600
but I find that to be incredible.
link |
00:38:44.800
The control variable there is the brain state.
link |
00:38:48.120
It's not what's spoken.
link |
00:38:51.360
You're raising a couple of very important issues, Andrew.
link |
00:38:56.360
We talked earlier about systematic desensitization
link |
00:38:59.160
where you sort of lay out a hierarchy of things
link |
00:39:02.680
and do it one at a time.
link |
00:39:04.200
I think of this as unsystematic desensitization
link |
00:39:07.400
because you're changing mental states.
link |
00:39:10.360
And I think there's more and more evidence
link |
00:39:12.360
that mental state change itself has therapeutic potential.
link |
00:39:15.320
We're seeing that with ketamine,
link |
00:39:16.960
treating depression as a sociogenic drug.
link |
00:39:20.800
We see it, we know it every morning
link |
00:39:22.680
when we wake up that problem.
link |
00:39:24.360
You made the mistake of reading a nasty email at 11 p.m.
link |
00:39:27.320
You didn't know what to do.
link |
00:39:28.400
You wake up in the morning and think,
link |
00:39:29.280
oh, that idiot, yeah, here's what I'm gonna do.
link |
00:39:31.720
So just changing mental state itself
link |
00:39:34.560
has therapeutic potential.
link |
00:39:36.000
And I think we underestimate our ability
link |
00:39:38.880
to regulate and change responses,
link |
00:39:41.360
to be cognitively, emotionally, and somatically flexible.
link |
00:39:46.440
And so we do things, you're right,
link |
00:39:48.520
that follow similar principles of facing a problem,
link |
00:39:51.440
seeing it from a different point of view.
link |
00:39:53.440
And you've done a really nice podcast on trauma and stress
link |
00:39:56.960
and how you have to expose yourself to it, not avoid it,
link |
00:40:00.680
as we talked about before,
link |
00:40:02.360
and then find some way to reconnect to it,
link |
00:40:06.240
to substitute something that can make you feel good
link |
00:40:08.640
rather than bad so that you activate other centers
link |
00:40:12.520
of the brain, like mesolimbic reward system.
link |
00:40:15.120
And so I do that with hypnosis,
link |
00:40:17.520
and you can do it much faster.
link |
00:40:19.960
People don't think they can, but they can.
link |
00:40:21.880
If you're having, right now, that physical experience,
link |
00:40:24.680
I'm thinking about this,
link |
00:40:25.520
but I'm not feeling as bad as I used to,
link |
00:40:28.960
that can be a powerful thing,
link |
00:40:30.520
and you can do it with hypnosis.
link |
00:40:32.040
So I had a woman came to see me
link |
00:40:34.840
who had suffered an attempted rape.
link |
00:40:36.840
It was getting dark.
link |
00:40:38.440
She was coming back from the grocery store,
link |
00:40:40.160
and this guy grabs her
link |
00:40:41.760
and wants to get her up into her apartment.
link |
00:40:43.640
It's outside her apartment.
link |
00:40:44.680
And she starts fighting with him,
link |
00:40:47.080
and she winds up with a basilar skull fracture.
link |
00:40:49.680
He runs away.
link |
00:40:51.280
The cops come.
link |
00:40:52.600
Since she hadn't been raped, they left.
link |
00:40:54.120
They weren't interested.
link |
00:40:54.960
And she wanted to use hypnosis
link |
00:40:56.920
to get a better image of what this guy looked like,
link |
00:40:59.400
which is a painful, upsetting thing.
link |
00:41:01.160
So she was quite hypnotizable.
link |
00:41:03.480
I got her floating.
link |
00:41:04.680
I say, you're safe and comfortable now.
link |
00:41:06.120
Nothing can happen that will harm your body.
link |
00:41:08.440
But on the left side of the screen,
link |
00:41:10.360
I want you to picture this guy
link |
00:41:12.440
and his approaching and what's happening.
link |
00:41:14.600
And she said, the light, it was getting dark.
link |
00:41:17.440
I really can't see much of his facial features,
link |
00:41:20.240
but I do recognize something
link |
00:41:21.800
I hadn't allowed myself to remember.
link |
00:41:24.000
If he gets me upstairs, he doesn't just wanna rape me.
link |
00:41:26.640
He's gonna kill me.
link |
00:41:28.200
And so in some ways,
link |
00:41:30.480
what she was seeing was even worse.
link |
00:41:31.800
So you're thinking good Spiegel.
link |
00:41:34.160
You made her even more frightened than she was before.
link |
00:41:37.000
But as you had pointed out in your PTSD stress lecture,
link |
00:41:40.600
you've got to confront the trauma
link |
00:41:42.240
to restructure your understanding of it.
link |
00:41:45.440
So on the other side of the screen, I had her picture.
link |
00:41:50.640
What are you doing to protect yourself?
link |
00:41:53.040
And everybody in a trauma situation
link |
00:41:54.840
engages in some strategy of self-protection.
link |
00:41:57.560
That's the Salience Network kicking in.
link |
00:41:59.840
And she said, you know what?
link |
00:42:02.560
He's surprised and I'm fighting that hard.
link |
00:42:05.000
He didn't think I would.
link |
00:42:06.720
And so she realized on the one hand
link |
00:42:08.640
that it was even worse than she thought it was.
link |
00:42:10.560
But on the other hand,
link |
00:42:11.440
that she actually probably saved her life.
link |
00:42:13.760
And so it was a way of helping her restructure
link |
00:42:17.480
her experience of the trauma and make it more tolerable.
link |
00:42:20.640
So that helped with her.
link |
00:42:22.280
She didn't recognize, she couldn't identify the guy,
link |
00:42:25.200
but it helped her restructure and understand her experience.
link |
00:42:29.080
And that's something that you can do
link |
00:42:31.080
in just talking straight out psychotherapy,
link |
00:42:33.840
but sometimes you can do a hell of a lot faster
link |
00:42:36.600
and more efficiently using hypnosis.
link |
00:42:39.160
And there is one randomized trial out of Israel
link |
00:42:41.640
that shows that adding hypnosis to PTSD treatment
link |
00:42:44.120
actually improves outcome.
link |
00:42:46.120
So it's a way of accomplishing things that we understand
link |
00:42:52.280
in the broader psychotherapy world,
link |
00:42:54.120
but much more quickly and sometimes effectively.
link |
00:42:58.360
Yeah, it sounds like going into,
link |
00:42:59.560
somewhat into the state that one is trying to deal with,
link |
00:43:03.120
but then dissociating from that state is key.
link |
00:43:05.560
And I could imagine,
link |
00:43:06.960
and I've been open about this on various podcasts.
link |
00:43:09.320
I've done a lot of analysis over the years.
link |
00:43:13.160
So, but I've experienced myself that in those sessions,
link |
00:43:17.400
depending on how I show up to them,
link |
00:43:19.120
I might just get in kind of a laundry list of what happened
link |
00:43:22.280
as opposed to actually feeling anything
link |
00:43:24.080
around what happened.
link |
00:43:26.280
And I think people probably varied
link |
00:43:27.680
in the extent to which they can drop into feeling states
link |
00:43:30.760
and it can depend on the day.
link |
00:43:33.240
It can depend on how well you slept the night before
link |
00:43:36.080
and so on.
link |
00:43:37.360
There's one thing I might add, Andrew,
link |
00:43:38.880
and that is, you know, there's a notion
link |
00:43:40.640
of the late Gordon Bauer.
link |
00:43:41.960
We just had a memorial for Gordon at Stanford.
link |
00:43:45.240
He died about a year ago.
link |
00:43:47.120
Brilliant cognitive psychologist.
link |
00:43:48.960
So one of the founders of cognitive psychology at Stanford
link |
00:43:52.200
and a great pitcher.
link |
00:43:53.280
He almost became a major league pitcher,
link |
00:43:55.400
but he decided to go to grad school instead.
link |
00:43:57.420
And I'm glad he did.
link |
00:43:59.920
But Gordon helped establish the concept
link |
00:44:03.080
of state-dependent memory,
link |
00:44:04.440
that when you're in a certain mental state,
link |
00:44:07.140
you enhance your ability to remember things about it.
link |
00:44:09.200
And the sort of the bad example of that
link |
00:44:11.120
is the drunk who hides the bottle
link |
00:44:12.800
and can't remember where he put it
link |
00:44:14.160
until he gets drunk again.
link |
00:44:15.240
That he's in that same mental state.
link |
00:44:18.220
People go into dissociative states when they're traumatized.
link |
00:44:22.480
So in a way, hypnosis is helping them remember
link |
00:44:26.080
and deal with the memories better
link |
00:44:27.360
because they're more in the mental state
link |
00:44:29.400
that is more like what happened.
link |
00:44:30.560
And most rape victims will tell you,
link |
00:44:32.880
I was floating above my body feeling sorry
link |
00:44:35.240
for the woman being assaulted below.
link |
00:44:39.660
People in traumatic episodes, they just say,
link |
00:44:42.240
you know, I blank out.
link |
00:44:43.120
I don't know what's happening.
link |
00:44:43.960
I'm on autopilot.
link |
00:44:44.960
And that's a kind of self-hypnotic state.
link |
00:44:47.320
So when you use hypnosis to help them deal
link |
00:44:50.520
with the traumatic memory,
link |
00:44:51.960
you're making the state they're in right there
link |
00:44:53.900
in your office with you more congruent
link |
00:44:56.460
to the state they were likely in when the trauma happened.
link |
00:44:59.200
And I think that is part of what helps facilitate treatment
link |
00:45:02.620
of trauma-related disorders.
link |
00:45:04.600
I see.
link |
00:45:05.840
So that makes me have to ask every question I have to ask
link |
00:45:09.400
because I really feel it as almost a compulsion.
link |
00:45:11.840
Then if dissociation during a traumatic episode
link |
00:45:15.680
is part of the adaptive strategy,
link |
00:45:20.080
but it creates certain issues.
link |
00:45:21.440
It creates problems, right?
link |
00:45:22.940
Why would something like ketamine,
link |
00:45:27.220
which creates a dissociative state,
link |
00:45:29.820
be useful for the treatment of trauma?
link |
00:45:32.300
This is what I'm confused about these days
link |
00:45:34.580
because our colleague, Carl Deisseroth,
link |
00:45:36.700
who's also been on this podcast
link |
00:45:38.060
and his coworkers have figured out,
link |
00:45:40.460
okay, there's these layer one networks in the neocortex,
link |
00:45:43.740
and those are involved in dissociative state.
link |
00:45:45.380
And so we're starting to gain some understanding
link |
00:45:46.680
of how ketamine works at a neural level.
link |
00:45:49.420
It does seem as if for certain populations,
link |
00:45:52.760
it can be a useful treatment.
link |
00:45:54.860
I don't know, I've never tried it.
link |
00:45:55.900
I don't know what the current status of that is,
link |
00:45:57.420
but it is legal.
link |
00:45:58.740
It is allowed, at least it's FDA approved and it's in use.
link |
00:46:03.280
Why would dissociative states be useful
link |
00:46:06.840
if some element of dissociation is what gave rise
link |
00:46:10.860
to the trauma memory in the first place?
link |
00:46:13.600
Well, yeah, Carl had a brilliant paper in Nature
link |
00:46:16.660
where it was from rats to humans in one paper.
link |
00:46:20.180
And he showed that there's this rhythmic discharge
link |
00:46:22.820
in the retrosplenial region that is associated,
link |
00:46:26.260
that is triggered by ketamine.
link |
00:46:28.060
And the rats actually showed dissociative-like behavior
link |
00:46:31.960
in that they would touch a hot pad
link |
00:46:34.100
that they ordinarily wouldn't,
link |
00:46:35.280
and they didn't seem to have much pain in their paw.
link |
00:46:37.340
And he then had a male subject
link |
00:46:40.500
who had implanted electrodes.
link |
00:46:43.100
Human.
link |
00:46:43.940
A human subject, yeah, human subject.
link |
00:46:45.580
And the electrodes had picked up this rhythmic activity,
link |
00:46:50.700
and when they did, he would report
link |
00:46:52.740
being in a dissociative state.
link |
00:46:54.100
And his description was,
link |
00:46:55.760
it's like being a pilot of an airplane,
link |
00:46:57.780
and then I felt myself walking out of the cockpit,
link |
00:47:00.560
and the plane was still flying.
link |
00:47:01.820
That sounds terrifying to me.
link |
00:47:03.900
That sounds terrifying.
link |
00:47:05.140
I want to be in my body most of the time.
link |
00:47:08.700
That's right, but the point is,
link |
00:47:11.340
in a way, the principle, Andrew,
link |
00:47:13.060
is like the principle you said,
link |
00:47:14.500
that you need to re-confront a traumatic situation
link |
00:47:17.900
before you can modulate your associations to it.
link |
00:47:21.280
So you have to accept it, accept the arousal,
link |
00:47:24.620
put some boundaries around it,
link |
00:47:25.860
and then figure out how you can approach that problem,
link |
00:47:28.300
or how you did approach that problem
link |
00:47:29.820
from a different point of view.
link |
00:47:31.300
So it does not surprise,
link |
00:47:32.980
in fact, we've studied people who dissociated
link |
00:47:36.020
during the Loma Prieta earthquake
link |
00:47:38.100
and the Oakland-Berkeley firestorm.
link |
00:47:40.380
I remember both of those well.
link |
00:47:41.900
Earthquakes follow me.
link |
00:47:42.820
And then I move south, and then the northridge.
link |
00:47:45.020
I'm going to keep it right here.
link |
00:47:45.860
So there'll be one layer this afternoon.
link |
00:47:47.180
I'm starting to dissociate, Andrew.
link |
00:47:50.380
So dissociation does compartmentalize experience,
link |
00:47:55.300
but that means, from the point of view of treating trauma,
link |
00:47:58.100
it's an inhibition.
link |
00:48:00.380
You don't engage it.
link |
00:48:01.500
It's like it happened over there.
link |
00:48:02.980
And I think what happens is that people
link |
00:48:05.740
are sometimes too good at being able to separate themselves
link |
00:48:08.740
from the recollection, so it's in there somewhere.
link |
00:48:11.540
It's out of sight, but it's not out of mind.
link |
00:48:13.320
It's having effects on you, but you can't deal with it.
link |
00:48:15.660
You can't reprocess it.
link |
00:48:17.300
So I do think one reason ketamine might work
link |
00:48:20.820
is that, in fact, it allows you to keep,
link |
00:48:25.500
to re-approach the dissociative experience
link |
00:48:29.060
in a way that you can then start to think about
link |
00:48:31.020
and do something about it.
link |
00:48:32.060
And just the fact you can turn it on and off.
link |
00:48:34.380
And that's also where self-hypnosis is so helpful.
link |
00:48:37.540
It's not something that just comes over you
link |
00:48:39.340
and happens to you, it's something you can make happen.
link |
00:48:41.540
You can control it.
link |
00:48:42.420
You can do something with it.
link |
00:48:43.820
So you feel less helpless and out of control.
link |
00:48:46.500
The essence of trauma is helplessness.
link |
00:48:48.380
It's not fear, it's not pain, it's helplessness.
link |
00:48:50.940
You become an object.
link |
00:48:52.580
You become just your body.
link |
00:48:54.140
You don't control what's going on,
link |
00:48:55.480
and we're not used to that.
link |
00:48:57.200
You and I have discussed this brilliant paper
link |
00:49:00.340
on anticipation of breathing,
link |
00:49:02.460
and it's not whether you breathe,
link |
00:49:04.300
inhale or exhale or hold your breath.
link |
00:49:06.780
It's that if you think you can inhale and you can't,
link |
00:49:10.260
that is really upsetting, understandably.
link |
00:49:12.660
And so the issue is control.
link |
00:49:15.020
And hypnosis, which has this terrible reputation
link |
00:49:18.080
of taking away control, is actually a superb way
link |
00:49:21.820
of enhancing your control over mind and body.
link |
00:49:25.700
I love that.
link |
00:49:26.540
And it reminds me that naming is so important.
link |
00:49:29.100
You almost wonder if self-hypnosis and clinical hypnosis
link |
00:49:32.600
had been called something else,
link |
00:49:34.540
that it would have been separated out from stage hypnosis
link |
00:49:38.220
in a way that would make it less scary, weird,
link |
00:49:44.260
complicated for people to embrace.
link |
00:49:46.700
But part of the reason for having this discussion
link |
00:49:49.420
is I've had great experiences with hypnosis.
link |
00:49:52.380
I've seen the data.
link |
00:49:54.180
We're talking about a lot of clinical examples.
link |
00:49:55.700
It's incredibly powerful,
link |
00:49:57.240
and it boils right down to neural brain states.
link |
00:50:01.340
And I think in the years to come,
link |
00:50:03.760
it's going to become more widespread.
link |
00:50:06.740
Along those lines, how quickly,
link |
00:50:09.300
you've described some examples
link |
00:50:11.700
of people getting relief very quickly.
link |
00:50:14.740
How permanent are those changes?
link |
00:50:18.380
Is there a need for follow-up?
link |
00:50:20.200
And related to that,
link |
00:50:21.560
I'm sure a number of people are listening to this
link |
00:50:23.180
and thinking, wonderful, I'd love to get hypnotized
link |
00:50:26.220
for any number of different things by Dr. Spiegel
link |
00:50:29.660
or somebody else expert in clinical hypnosis,
link |
00:50:32.380
but they might not have access to you or somebody
link |
00:50:36.140
with similar training.
link |
00:50:37.420
So what is the power?
link |
00:50:39.220
So how quickly does it work?
link |
00:50:40.940
How long lasting are those changes?
link |
00:50:43.000
And then is it necessary to work with a clinical hypnotist?
link |
00:50:46.980
And is it better to do that than self-hypnosis
link |
00:50:49.760
and so on and so forth?
link |
00:50:50.700
Maybe you could just give us a contour of the landscape
link |
00:50:53.620
of directed and self-directed treatment.
link |
00:50:56.220
Well, typically most people start
link |
00:51:01.020
by coming to see a clinician like me.
link |
00:51:03.220
It's better to see someone who has licensing and training
link |
00:51:06.580
in their professional discipline,
link |
00:51:08.700
medicine, psychology, dentistry, whatever.
link |
00:51:11.860
Because there are a lot of hypnotists out there
link |
00:51:13.220
who are just hypnotists.
link |
00:51:14.260
Just hypnotists.
link |
00:51:15.460
Okay.
link |
00:51:16.300
And the key issue is somebody who can really assess
link |
00:51:18.920
what your problem is and make sure
link |
00:51:20.420
that you're not talking someone
link |
00:51:21.740
into reducing their chest pain
link |
00:51:22.980
rather than getting their coronary artery problem.
link |
00:51:26.240
Because they could have a real issue there.
link |
00:51:27.580
They could, right.
link |
00:51:28.420
Hypnosis might adjust but wouldn't deal
link |
00:51:31.380
with the deeper underlying issue.
link |
00:51:33.140
That's right.
link |
00:51:33.980
On the other hand, and typically when I use it with people,
link |
00:51:37.060
I often only see them once or twice or periodically
link |
00:51:39.700
but not every week.
link |
00:51:41.020
And certainly not every day if they have a pain problem.
link |
00:51:43.340
And hypnosis is very helpful for pain.
link |
00:51:46.580
And so what I'm doing is identifying
link |
00:51:51.040
how hypnotizable they are.
link |
00:51:52.220
I give them a standard brief test
link |
00:51:53.900
of their ability to experience hypnosis.
link |
00:51:55.860
And then going through a self-hypnosis exercise
link |
00:51:58.860
with them to deal with the problem.
link |
00:52:00.480
Seeing how they respond to it.
link |
00:52:02.180
And then teaching them how to do it for themselves.
link |
00:52:04.940
And in the old days I used to have them
link |
00:52:06.980
use their iPhone and record that part of the session
link |
00:52:12.040
so they could play back the hypnosis experience.
link |
00:52:15.020
Now we've developed an app, Reverie,
link |
00:52:18.100
that can teach people and step them through
link |
00:52:22.740
dealing with pain, stress, focus, insomnia,
link |
00:52:27.460
and help people eat better and stop smoking.
link |
00:52:31.500
And we have elements that take about 15 minutes
link |
00:52:35.240
and elements that just take one or two minutes
link |
00:52:37.120
that people can refresh and reinforce.
link |
00:52:39.220
So the idea- Two minute hypnosis.
link |
00:52:40.420
Yes, yes.
link |
00:52:41.500
And it's one to two minutes now.
link |
00:52:44.620
And we're finding that two thirds of the people
link |
00:52:46.620
find that even just the one minute refresher
link |
00:52:49.700
helps them feel better.
link |
00:52:50.820
They're reporting they feel better.
link |
00:52:52.060
So the nice thing is you know right away
link |
00:52:53.940
whether it's likely to help you or not.
link |
00:52:56.780
And we've found, we've done studies looking at hypnosis
link |
00:53:00.500
for pain relief in acute medical procedures.
link |
00:53:03.340
We did a randomized trial that we published in The Lancet.
link |
00:53:06.580
Three conditions, people getting arterial cut downs
link |
00:53:10.000
to chemoembolized tumors in the liver
link |
00:53:12.420
or visualized renal artery stenosis.
link |
00:53:14.740
You don't use general anesthesia for this.
link |
00:53:16.340
It's very uncomfortable and people are anxious.
link |
00:53:18.420
And we had three conditions.
link |
00:53:19.700
One was standard care, they could push a button
link |
00:53:22.340
and get opioids, IV.
link |
00:53:24.940
Is during the surgery.
link |
00:53:25.940
During the surgery.
link |
00:53:26.780
The second is they could do that
link |
00:53:28.240
plus they had a friendly nurse comforting them.
link |
00:53:30.660
So we controlled for pleasant attention and support.
link |
00:53:33.500
And the third was we taught them self hypnosis
link |
00:53:35.760
for pain control.
link |
00:53:36.600
So you're feeling, you can change the temperature.
link |
00:53:39.500
Your body is cool, tingling and numb.
link |
00:53:41.620
You're floating in ice water and feeling comfortable.
link |
00:53:45.880
Or go somewhere else.
link |
00:53:47.060
Leave your body here and go to a desert island
link |
00:53:49.740
and enjoy yourself.
link |
00:53:51.780
And we found that it's about two and a half hour procedure
link |
00:53:55.900
that by an hour and a half, the hypnosis group
link |
00:53:59.740
had reduced their pain by 80%
link |
00:54:02.960
compared to the standard care group
link |
00:54:04.780
using half the amount of opioids.
link |
00:54:07.140
They had fewer complications
link |
00:54:09.060
and the procedure took 17 minutes less time on average
link |
00:54:12.380
to get done because not only was the patient more relaxed,
link |
00:54:14.660
so was the treatment staff.
link |
00:54:15.880
They weren't dealing with someone
link |
00:54:17.580
who was struggling and uncomfortable.
link |
00:54:19.540
We measured their anxiety.
link |
00:54:21.220
And same thing, the hypnosis group,
link |
00:54:22.740
I was worried they were all dead.
link |
00:54:23.940
They had no anxiety after an hour and a half.
link |
00:54:25.980
They were saying I'm fine, you know.
link |
00:54:27.660
And they were fine.
link |
00:54:28.980
And the standard care group had five out of 10
link |
00:54:32.100
anxiety scores at that point.
link |
00:54:33.860
So we published that in The Lancet.
link |
00:54:36.280
Big randomized trial.
link |
00:54:38.460
If we had a drug that did that,
link |
00:54:40.860
every hospital in the country would be using it now.
link |
00:54:44.300
But there's no industry to push it.
link |
00:54:46.300
So that's part of what helped us decide
link |
00:54:48.880
that we needed to help people do this with Reverie
link |
00:54:52.700
and teach them how to do it
link |
00:54:54.060
and provide interactive support for them to do it.
link |
00:54:57.820
And the question, although, is does it work long term?
link |
00:55:01.980
Because what we can do acutely
link |
00:55:03.460
doesn't necessarily carry on.
link |
00:55:05.080
So we did a randomized trial of women
link |
00:55:07.700
with metastatic breast cancer.
link |
00:55:09.000
They had advancing disease.
link |
00:55:10.940
We met with them in a support group once a week
link |
00:55:13.000
and taught them self-hypnosis for stress and anxiety
link |
00:55:16.660
and pain control at the end.
link |
00:55:18.100
And by the end of a year,
link |
00:55:20.660
the treatment group had half the pain the control group did
link |
00:55:23.120
on the same and very low amounts of medication.
link |
00:55:25.580
So it lasts.
link |
00:55:26.500
And they would say when I felt that pain in my chest
link |
00:55:29.820
and thought it was a metastasis, I just did the exercise.
link |
00:55:32.980
I got myself in a warm bath and I felt fine.
link |
00:55:35.620
So it works because it becomes a skill that people acquire.
link |
00:55:40.660
But they can tell right away
link |
00:55:42.040
whether it's likely to help them working with a clinician
link |
00:55:44.660
or now using the app or other ways of helping them learn
link |
00:55:48.900
to use it as a skill.
link |
00:55:50.100
So the nice thing is you will know very quickly
link |
00:55:52.960
whether it's likely to help you or not.
link |
00:55:54.420
And if it is, you can learn to do it for yourself.
link |
00:55:57.100
That's great.
link |
00:55:57.940
And we will, again, there'll be a link to Reverie
link |
00:56:00.760
in the caption that's available for Apple and Android.
link |
00:56:04.100
And I think even though there's a nominal cost there,
link |
00:56:07.400
I think that, as you mentioned, medications
link |
00:56:12.320
and other approaches to dealing with these problems
link |
00:56:14.900
are quite expensive and have all the potential
link |
00:56:18.960
for side effects and things.
link |
00:56:20.220
Not that some of those aren't also useful.
link |
00:56:22.120
Could I, before you get to that, just one thing.
link |
00:56:24.300
We've worked very hard on the app.
link |
00:56:27.060
We have an iOS app for Apple.
link |
00:56:29.620
We decided to table for a moment redoing the Android app.
link |
00:56:33.500
So it's not, it was available when we were working
link |
00:56:37.860
through the Alexa platform.
link |
00:56:39.660
It's not at the moment, but it will be soon.
link |
00:56:41.780
So I just don't want people to be disappointed
link |
00:56:44.020
if they're looking for it for Android.
link |
00:56:45.660
It's on our agenda, but we don't have it at the moment.
link |
00:56:48.700
Great, thanks for that clarification.
link |
00:56:50.300
So hopefully in time for both.
link |
00:56:53.300
I get asked a lot about obsessive thoughts
link |
00:56:56.680
or intrusive thoughts.
link |
00:56:58.700
I also get asked a lot about OCD.
link |
00:57:01.300
Is there any evidence that hypnosis or self-hypnosis
link |
00:57:04.300
can be used for dealing with obsessive thoughts?
link |
00:57:09.620
Sometimes.
link |
00:57:10.460
There are some very obsessional people
link |
00:57:12.500
who just turn out not to be that hypnotizable,
link |
00:57:15.300
and it's not random.
link |
00:57:16.300
They tend to be so over-controlling of thought.
link |
00:57:19.420
They're all busy evaluating rather than experiencing.
link |
00:57:23.000
So in some ways-
link |
00:57:23.840
I know a few people like that.
link |
00:57:24.660
I mean, me too.
link |
00:57:26.020
Sounds like a, it sounds like an adaptive mindset
link |
00:57:28.920
for a lot of professions in areas,
link |
00:57:31.380
and that we get trained up in that during school,
link |
00:57:34.900
how to obsess over the exam,
link |
00:57:36.620
obsess over our social interactions.
link |
00:57:40.280
I mean, it's part of becoming a functional human being,
link |
00:57:42.560
and yet you can take us down a different-
link |
00:57:45.260
We sometimes overdo it.
link |
00:57:46.420
I mean, I'll tell you one example from extreme situations,
link |
00:57:50.100
because you're judging, evaluating,
link |
00:57:52.820
you're not letting yourself experience,
link |
00:57:54.180
including emotionally.
link |
00:57:55.700
I know somebody who listens to the tapes from airplanes
link |
00:57:59.820
that they go down, so they get the black box
link |
00:58:01.940
and they listen to it, and he said to me, you know-
link |
00:58:04.780
That's his profession, or he does this recreationally?
link |
00:58:06.260
No, it's his profession, that's what he did,
link |
00:58:09.420
because they're trying to do accident prevention
link |
00:58:11.220
and how to handle things.
link |
00:58:12.420
And he said that you worry about people panicking, right?
link |
00:58:17.420
And here, these guys know that they've got 30 seconds,
link |
00:58:20.740
or some 45 seconds,
link |
00:58:22.100
and they're just going through their checklist.
link |
00:58:24.500
He said they don't panic enough.
link |
00:58:26.980
They're taught that this is what you do,
link |
00:58:28.840
and there is reason, there's good reason for it,
link |
00:58:31.360
but sometimes they overdo it.
link |
00:58:33.580
And it's painful to listen to this,
link |
00:58:36.340
because you know what's going to happen.
link |
00:58:37.500
So it's kind of a balance we have to hit,
link |
00:58:40.260
and sometimes we get too emotional and too absorbed,
link |
00:58:43.540
and you're not with it enough
link |
00:58:46.140
to sort of see other possibilities.
link |
00:58:48.260
That can be a problem.
link |
00:58:49.100
But on the other hand, sometimes you're too rigid
link |
00:58:51.380
and controlled, and you don't let your emotions guide you
link |
00:58:54.460
to what you need to do to protect yourself
link |
00:58:56.820
or protect others.
link |
00:58:57.660
So I would say in general that people with OCD
link |
00:59:01.860
are on the less hypnotizable side of the spectrum.
link |
00:59:05.840
They're less likely to allow themselves
link |
00:59:07.580
to engage in anything.
link |
00:59:08.460
And the typical example is the checking with OCD,
link |
00:59:11.260
for example.
link |
00:59:12.180
They don't remember whether they locked the door
link |
00:59:17.020
or turned off the gas in the oven,
link |
00:59:18.380
and they keep going back, and they keep checking.
link |
00:59:20.100
So there, the evaluative component of the brain
link |
00:59:23.560
kind of overrides the experiential one.
link |
00:59:26.140
And sometimes people can get some benefit,
link |
00:59:29.340
but they're not a group that I would select
link |
00:59:32.420
for being the most likely to respond
link |
00:59:35.100
to self-hypnotic approaches.
link |
00:59:37.140
Are superstitions similar?
link |
00:59:40.460
Superstitions, I think that's more.
link |
00:59:44.240
There are people who are very hypnotizable
link |
00:59:47.740
who keep getting caught up in things like superstitions.
link |
00:59:51.060
And there, the imagination supplants the reality.
link |
00:59:55.220
And we've seen a lot of that happening recently.
link |
00:59:58.120
And so I think there it's possible
link |
01:00:02.180
that they could be helped by learning to sort of see it,
link |
01:00:05.260
but put it in context,
link |
01:00:06.980
see it from a different point of view.
link |
01:00:09.020
I developed a pretty vicious superstition
link |
01:00:11.080
when I was in college, and it was hard to break, actually.
link |
01:00:14.820
I always feel that when I talk to clinicians,
link |
01:00:16.900
I have to reveal certain things about my own pathology.
link |
01:00:19.860
You'll get my bill later.
link |
01:00:21.340
Yes, it's part of the reason I arranged this,
link |
01:00:23.620
I'm just kidding.
link |
01:00:24.460
But yeah, I did.
link |
01:00:25.300
I had a habit of knocking on wood for things,
link |
01:00:28.180
and I noticed it started to,
link |
01:00:32.900
I would sneak knocking on wood every once in a while,
link |
01:00:35.500
because I didn't want people to think I was doing too often.
link |
01:00:37.340
And then I started to realize
link |
01:00:38.180
that it was becoming a little bit of a reflex.
link |
01:00:41.420
And then I saw this incredible video
link |
01:00:43.780
from Ben Solevsky's lab at Harvard.
link |
01:00:45.840
He studies motor patterns.
link |
01:00:47.500
He has these rats that press different sequences
link |
01:00:49.760
of levers and turn dials in order to get a pellet of food.
link |
01:00:54.420
But that as they do that,
link |
01:00:55.460
they'll start to introduce these behaviors
link |
01:00:56.980
that have nothing to do with the actual lever pressing.
link |
01:00:59.900
They'll start scratching their hindquarters
link |
01:01:02.180
and things like that, and their head,
link |
01:01:04.600
excuse me, they don't wear hats, and flipping their ears.
link |
01:01:06.700
And this is just like a pitcher before throwing a baseball.
link |
01:01:12.060
We do this, we start to incorporate motor behaviors
link |
01:01:15.180
that are unrelated to the outcome,
link |
01:01:17.200
but our mind somehow starts to think
link |
01:01:19.700
that they're necessary for the outcome.
link |
01:01:21.600
And so then you incorporate it.
link |
01:01:22.660
So I decided to break it by simply forcing myself
link |
01:01:25.020
to not do it for about a week.
link |
01:01:26.860
And then it just seemed like a ridiculous thing to do.
link |
01:01:29.780
Knock on wood.
link |
01:01:30.860
We call it response prevention, and it works.
link |
01:01:33.420
Because what you do is you set up a new context
link |
01:01:36.780
in your brain where you get the outcome you want
link |
01:01:39.580
devoid of the extraneous behavior.
link |
01:01:43.040
And I knew it was nuts, right?
link |
01:01:44.800
I knew it was illogical,
link |
01:01:46.300
but somehow these things take on meaning.
link |
01:01:49.720
So we talked about stress reduction,
link |
01:01:51.460
the utility of hypnosis for stress reduction,
link |
01:01:55.220
phobias, pain, possibly, we don't know,
link |
01:01:58.860
but for things like ADHD and OCD,
link |
01:02:01.580
it just will depend on hypnotizability.
link |
01:02:04.980
You talked about this beautiful study
link |
01:02:06.640
on the metastatic breast cancer outcome or patients.
link |
01:02:13.060
Hypnotizability is clearly a key variable.
link |
01:02:16.020
So could you please tell us what hypnotizability is,
link |
01:02:20.700
how it's evaluated, and what the Spiegel eye roll test is?
link |
01:02:25.060
Okay, sure.
link |
01:02:25.880
So hypnotizability is just a capacity
link |
01:02:31.360
to have hypnotic experiences.
link |
01:02:33.220
And we have a test called the hypnotic induction profile,
link |
01:02:35.920
where we give a highly structured hypnotic experience.
link |
01:02:39.540
And you know, the old tradition in clinical hypnosis
link |
01:02:42.620
was that you try a bunch of different things,
link |
01:02:45.060
walking upstairs and downstairs and other images,
link |
01:02:48.460
and time what you say to the breathing of the subject
link |
01:02:51.600
and all that.
link |
01:02:52.440
And the more you change what you do as a clinician,
link |
01:02:55.860
the less you can make a variation in outcome.
link |
01:02:59.020
And it could take a long time, you know,
link |
01:03:00.820
20 minutes, 30 minutes.
link |
01:03:02.820
And I just view that as a kind of complex,
link |
01:03:05.900
not very effective way of assessing
link |
01:03:07.620
the person's hypnotic capacity.
link |
01:03:09.700
We know that the peak period of hypnotizability
link |
01:03:13.120
in the human life is the latency years in childhood.
link |
01:03:16.180
So every eight-year-old is in a trance all the time.
link |
01:03:19.060
You know, you call them in for dinner,
link |
01:03:20.220
they don't hear you, they're doing their thing.
link |
01:03:21.940
And that's why childhood is such a wonderful experience.
link |
01:03:24.500
Work and play are all the same thing, you know.
link |
01:03:26.980
And we try to make them into little adults,
link |
01:03:29.060
which I think is a terrible mistake.
link |
01:03:30.860
They, everything is fun for them.
link |
01:03:32.500
They enjoy learning, they enjoy everything.
link |
01:03:34.660
So what age are they in this?
link |
01:03:36.780
This is like six to 10, six to 11.
link |
01:03:40.180
They're playful, they enjoy everything.
link |
01:03:42.400
Everything is sort of a game and fun.
link |
01:03:44.600
And we try to make it miserable for them,
link |
01:03:46.420
but they've got it.
link |
01:03:47.940
And then when what Piaget called, you know,
link |
01:03:51.500
a more adult cognitive framework,
link |
01:03:53.640
where we learn abstract concepts,
link |
01:03:56.260
we learn that even if one bottle looks bigger than the other
link |
01:03:58.740
they can have equal volume.
link |
01:04:00.000
And so we start imposing logic.
link |
01:04:02.040
We're growing our DLPFC at that point,
link |
01:04:04.760
and imposing cognitive structure on experience.
link |
01:04:08.880
Some people start to lose that hypnotic ability.
link |
01:04:12.380
By the time you're in your early 20s,
link |
01:04:16.440
your hypnotized ability becomes extremely fixed.
link |
01:04:19.900
And there was a study done at Stanford,
link |
01:04:22.540
Ernest Hilgard, Phil Zimbardo did this,
link |
01:04:24.940
looking at, they tracked down students who were in Psych 1,
link |
01:04:31.040
had their hypnotized ability measured,
link |
01:04:32.780
and retested them blindly 25 years later.
link |
01:04:35.740
And the test-retest correlation was,
link |
01:04:38.160
you want to guess what it was?
link |
01:04:40.200
I'm guessing it's, I don't know, 0.6 something.
link |
01:04:44.840
Yeah, very close.
link |
01:04:46.120
It was 0.7, IQ would be 0.6 on a 25 year interval.
link |
01:04:50.200
So it's more stable than IQ over a 25 year interval.
link |
01:04:53.120
So once you're at that point, that's where you are.
link |
01:04:57.020
What are the factors that lead to that?
link |
01:04:59.520
Well, and so what it means is that about a third of adults
link |
01:05:02.500
are just not hypnotizable.
link |
01:05:04.240
Two thirds are, about 15% are extremely hypnotizable.
link |
01:05:07.720
And we can measure that and give it a number
link |
01:05:09.320
from zero to 10.
link |
01:05:11.020
And that's very useful.
link |
01:05:12.340
For some of my patients when I do it,
link |
01:05:14.320
I say, look, I'm sorry, you're not hypnotizable,
link |
01:05:16.120
we're gonna do something else.
link |
01:05:17.780
Medication, systematic desensitization,
link |
01:05:20.520
mindfulness, other things.
link |
01:05:22.720
Or if they're very hypnotizable, I just go for it.
link |
01:05:25.880
I don't do a lot of explaining.
link |
01:05:27.520
People who are low to moderate hypnotizable
link |
01:05:30.080
like explanations about what you're doing,
link |
01:05:31.920
but then they can still get the benefits.
link |
01:05:34.120
So it helps me guide the nature of my treatment
link |
01:05:38.200
with these people.
link |
01:05:39.040
Now, the eye roll is,
link |
01:05:40.760
my father used to use an eye fixation induction.
link |
01:05:45.280
He used to say, look up at the ceiling
link |
01:05:47.920
and now close your eyes while you're looking up.
link |
01:05:50.920
You're very, yes, you're very hypnotizable.
link |
01:05:53.560
So he noticed, he had two patients back to back.
link |
01:05:57.520
And one was a woman who I'd seen him work with
link |
01:05:59.560
who had hysterical seizures.
link |
01:06:01.920
She would just suddenly start shaking.
link |
01:06:05.000
Real epileptic seizures.
link |
01:06:06.360
No, pseudo epileptics.
link |
01:06:07.520
I see, so hysteria.
link |
01:06:08.960
Hysteria.
link |
01:06:09.800
And although some people have both,
link |
01:06:11.360
that is for some people,
link |
01:06:13.600
real epilepsy becomes a framework
link |
01:06:15.880
that gets elaborated on for when you're stressed,
link |
01:06:18.840
you have seizures.
link |
01:06:19.680
She just had pseudo epilepsy, no EEG abnormalities.
link |
01:06:23.080
And she, it was really something to watch.
link |
01:06:25.280
Her husband had to move his workbench near the door
link |
01:06:29.040
so that if she started to have a seizure,
link |
01:06:30.440
he could run home and try and help her with it.
link |
01:06:32.600
It was that bad.
link |
01:06:34.040
And he noticed that when she did what you did,
link |
01:06:38.040
when she looked up, when she would have
link |
01:06:39.560
one of her seizure events, all you see is sclera.
link |
01:06:42.360
You don't see iris anymore.
link |
01:06:44.280
And she would start to see.
link |
01:06:45.440
So he did a great thing with her.
link |
01:06:47.600
He taught her to have seizures.
link |
01:06:49.040
Everybody else was telling her to stop.
link |
01:06:51.160
He made her have one.
link |
01:06:52.040
So he hypnotized her.
link |
01:06:53.040
Let's go back to the last time you had one.
link |
01:06:54.760
And sure enough, she'd start to shake.
link |
01:06:56.360
And gradually, he'd make them smaller and smaller.
link |
01:06:59.480
So she was learning.
link |
01:07:00.480
She could control.
link |
01:07:01.360
She'd have access.
link |
01:07:02.260
It's like with PTSD.
link |
01:07:03.960
You confront, you don't avoid it.
link |
01:07:05.640
You don't suppress it.
link |
01:07:06.760
You confront it and figure out how to deal with it.
link |
01:07:10.640
The next patient he had
link |
01:07:11.800
was a rigid, obsessional businessman
link |
01:07:14.560
who wanted to stop being so controlling and all this.
link |
01:07:19.560
Remind me, there was a New Yorker cartoon of a driver
link |
01:07:22.080
who comes to a yield sign and he yells, never.
link |
01:07:25.040
It's always being controlled.
link |
01:07:26.880
Sounds about right.
link |
01:07:27.720
You're a New Yorker.
link |
01:07:28.540
I'm a New Yorker, right.
link |
01:07:30.280
And so this guy, when he tried to look up,
link |
01:07:34.040
he couldn't keep his eyes up while he closed them.
link |
01:07:36.240
And so my father started testing people.
link |
01:07:40.480
And it seemed that there is a rough correlation
link |
01:07:43.420
between the capacity to keep your eyes up
link |
01:07:45.420
while you close them and measured hypnotizability.
link |
01:07:48.360
So that people who are listening
link |
01:07:51.960
and watching on video.
link |
01:07:53.080
So the Spigot eye roll test involves looking up
link |
01:07:55.880
at the ceiling.
link |
01:07:56.720
So it's tilting the head back.
link |
01:07:57.600
I'm tilting my chin back and looking up at the ceiling now.
link |
01:07:59.740
But I'm also directing my eyes upward and my eyes are open.
link |
01:08:04.040
And then the eye roll test involves then
link |
01:08:07.560
closing the eyelids while the eyes are open.
link |
01:08:10.520
And whether or not the eyes roll back.
link |
01:08:13.160
And as you said, then you see sclera, the white part.
link |
01:08:15.960
You see sclera, the white part.
link |
01:08:16.800
That means you're very hypnotizable
link |
01:08:18.700
or moderately hypnotizable.
link |
01:08:20.400
Whereas if the eyes move down and you see iris,
link |
01:08:22.800
the colored part of the eye, as the eyes close,
link |
01:08:25.280
less hypnotizable.
link |
01:08:27.080
And you can look this up online there.
link |
01:08:28.520
You just put Spigot eye roll test and you'll find it.
link |
01:08:32.880
And we are also gonna do an actual example
link |
01:08:36.240
of hypnosis on video later.
link |
01:08:38.560
Right, so you're asking the brain to do something difficult
link |
01:08:42.600
to keep the eyes up while closing the eyelids.
link |
01:08:46.840
And so that's contradictory signals for the third,
link |
01:08:49.880
fourth, and sixth cranial nerve nuclei
link |
01:08:51.580
that control eye movement.
link |
01:08:53.620
You said the third?
link |
01:08:54.480
Fourth and sixth cranial nerve nuclei.
link |
01:08:57.400
And so you're suspending one activity while asking them
link |
01:09:02.400
to do another, and eye movements have a lot to do
link |
01:09:05.860
with levels of consciousness.
link |
01:09:07.460
The periaqueductal gray surrounds
link |
01:09:09.820
these cranial nerve nuclei.
link |
01:09:11.740
And when we close our eyes when we sleep,
link |
01:09:15.460
we have rapid eye movement when we dream.
link |
01:09:17.520
Most drugs that affect level of consciousness
link |
01:09:19.520
can affect eyes and eye movements,
link |
01:09:21.380
either the dilation or contraction of the pupils,
link |
01:09:24.260
depending on whether it's a stimulant or an opioid.
link |
01:09:27.220
Stimulants make the pupils big.
link |
01:09:29.100
Right.
link |
01:09:29.940
Yeah, like cocaine, amphetamine.
link |
01:09:31.740
Right, exactly.
link |
01:09:32.560
Things of that sort.
link |
01:09:33.400
And opioids, you get constricted pupils.
link |
01:09:36.740
This is what parents, you know,
link |
01:09:37.940
the parents looking at their kids
link |
01:09:39.100
coming in the door late at night,
link |
01:09:40.460
they're looking for substance abuse.
link |
01:09:44.060
That's right.
link |
01:09:44.900
So there's something about the eyes
link |
01:09:47.540
that has a lot to do with level of consciousness.
link |
01:09:49.500
I mean, obviously, you close your eyes when you go to sleep,
link |
01:09:52.220
you have rapid eye movement when you're dreaming.
link |
01:09:54.500
So it's not surprising.
link |
01:09:56.060
And there's an old Zen practice
link |
01:09:57.800
called looking at the third eye.
link |
01:09:59.860
And I think part of the reason that this happens
link |
01:10:02.860
is where you're looking up inside.
link |
01:10:05.460
It's like there's a third eye
link |
01:10:06.520
between the other two in your forehead.
link |
01:10:08.700
And I think it's because we're visual creatures.
link |
01:10:12.300
You know, we're pretty pathetic
link |
01:10:14.500
from a physical point of view.
link |
01:10:15.660
You know, many animals can outrun us, you know,
link |
01:10:19.780
or outsmell us or see, you know,
link |
01:10:21.580
eagles could read the newsprint at 100 yards
link |
01:10:24.900
and we can't, you know, it's.
link |
01:10:26.460
So our major defensive sensory input is vision.
link |
01:10:32.980
And that's why, you know, animals, predator animals
link |
01:10:36.860
have eyes in the front of their head
link |
01:10:38.300
so that they have very good detailed vision of prey,
link |
01:10:42.200
whereas prey animals like deer
link |
01:10:44.500
have eyes on the side of their head.
link |
01:10:45.900
So they don't see things that well,
link |
01:10:47.140
but they have a much bigger range
link |
01:10:49.300
of potential to see threat.
link |
01:10:52.560
And we mainly use, and in fact, it's interesting,
link |
01:10:55.660
there have been social anthropologists that say,
link |
01:10:57.500
why do we gather where we do, you know, on coastlines
link |
01:11:01.180
and, you know, at the edge of a forest or something?
link |
01:11:03.940
It's because you've got protection in the back.
link |
01:11:06.500
Something can't attack you from one side
link |
01:11:08.540
and you have a big vision of what might threaten you.
link |
01:11:11.340
And we tend to like be attracted
link |
01:11:13.380
to those kinds of physical situations.
link |
01:11:16.460
So.
link |
01:11:17.280
And we love vistas.
link |
01:11:18.120
We love vistas.
link |
01:11:18.940
Vistas are very calming.
link |
01:11:19.780
They take us into that panoramic vision.
link |
01:11:21.480
That's right.
link |
01:11:22.320
I didn't know this, but it turns out
link |
01:11:23.540
that most of the scenic spots at any location
link |
01:11:26.860
in national parks were where people naturally aggregated.
link |
01:11:30.260
It wasn't, which makes sense, you know,
link |
01:11:32.820
but that those signs and locations
link |
01:11:35.860
were built up around people's tendency
link |
01:11:38.220
and animals' tendencies to aggregate there.
link |
01:11:41.700
Yeah, there's an interesting book
link |
01:11:43.620
on the history of the national parks
link |
01:11:44.860
that says that they didn't give a research study
link |
01:11:48.020
to support it, but there was no Google maps, obviously.
link |
01:11:50.540
That's very interesting.
link |
01:11:51.580
Yeah, panorama and visual boundaries
link |
01:11:54.380
are really interesting.
link |
01:11:55.380
I think, so the eyes, as we both know,
link |
01:11:57.900
are two pieces of the central nervous system
link |
01:12:00.020
of the brain outside the,
link |
01:12:02.340
I used to say that the eyes are outside the skull
link |
01:12:04.540
and a neuro-ophthalmologist wrote to me
link |
01:12:08.780
and vehemently pointed out
link |
01:12:11.340
that they are outside the cranial vault.
link |
01:12:13.380
So, you know, they're outside the cranial vault,
link |
01:12:15.820
but they are two pieces of brain.
link |
01:12:16.940
They're out there.
link |
01:12:17.860
And so you mentioned cranial nerves, three, four, and six.
link |
01:12:21.020
This isn't a neuroanatomy course,
link |
01:12:22.380
but maybe we could go a little deeper there.
link |
01:12:24.580
So there's, you said there's contradictory activity.
link |
01:12:26.660
Looking up is controlled by the one set of cranial nerves
link |
01:12:31.500
and then the closing of the eyelids
link |
01:12:32.820
is controlled by another cranial nerve.
link |
01:12:35.780
No, it's the same one.
link |
01:12:36.940
I think it's six that when you close your eyes,
link |
01:12:42.260
you activate, no, it's the facial,
link |
01:12:46.540
I guess it's the facial nerve.
link |
01:12:47.740
It's seven, seven, yeah.
link |
01:12:50.220
But you're looking up,
link |
01:12:52.380
you're activating the muscles
link |
01:12:55.380
that force your eyes to look up
link |
01:12:58.100
and closing your eyelids normally relaxes those,
link |
01:13:02.660
relaxes that upper movement
link |
01:13:04.260
because your eyes are closed and you don't need to do it.
link |
01:13:06.720
So you're breaking a usual customary pattern.
link |
01:13:10.020
It's like the rubbing, hey, I can't even do it.
link |
01:13:12.180
See, it's like the,
link |
01:13:14.700
rubbing your tummy and patting your head.
link |
01:13:17.180
There's a bit of a conflict there.
link |
01:13:19.140
But clinically it's been a good probe for you
link |
01:13:22.060
and for your father.
link |
01:13:23.340
So was it Spiegel Senior or Spiegel Junior?
link |
01:13:25.380
That's Spiegel Senior.
link |
01:13:26.340
That developed the Spiegel Eye Roll Test.
link |
01:13:28.740
But the key issue is this,
link |
01:13:30.100
that normally when we close our eyes also,
link |
01:13:32.980
we're going to sleep.
link |
01:13:34.340
You're not worried about what's going on
link |
01:13:36.060
in the world anymore.
link |
01:13:37.020
Here, you're maintaining resting alertness.
link |
01:13:40.180
So you're focusing, but you're turning inward.
link |
01:13:42.980
That's an unusual state.
link |
01:13:44.300
Normally we close our eyes periodically.
link |
01:13:46.620
We have to, but when you close your eyes
link |
01:13:49.380
for some period of time, it's normally to go to sleep.
link |
01:13:51.820
And you're not worried about detecting risk or threat.
link |
01:13:56.740
So it's an interesting state
link |
01:13:58.660
because you're turning inward basically.
link |
01:14:01.180
You're looking up, you're shutting your eyes
link |
01:14:03.300
and you're allowing whatever happens outside you to happen
link |
01:14:05.820
and focusing on what's going on inward.
link |
01:14:08.220
So I think it's a signal to your brain to turn inward.
link |
01:14:12.020
Very interesting.
link |
01:14:13.380
And meditation of course could be done with eyes open,
link |
01:14:16.460
but almost always is done with eyes closed.
link |
01:14:18.580
Yes, that's right.
link |
01:14:20.100
Very interesting.
link |
01:14:21.340
So you can very quickly determine
link |
01:14:24.020
whether or not someone is highly hypnotizable,
link |
01:14:27.220
not at all hypnotized.
link |
01:14:28.180
When you say about two thirds of people can be hypnotized,
link |
01:14:31.580
obviously a third cannot,
link |
01:14:32.780
but within the two thirds that can, there's a range.
link |
01:14:35.980
And you said 15% of people fall
link |
01:14:37.860
into this highly hypnotizable category
link |
01:14:40.780
that I seem to be a member of.
link |
01:14:42.780
And does repeated use of self-hypnosis
link |
01:14:46.020
or clinical hypnosis increase or change hypnotizability
link |
01:14:49.260
for those that can access it in the first place?
link |
01:14:51.380
I would say in general, it may increase a little bit,
link |
01:14:53.900
but not a hell of a lot.
link |
01:14:55.060
And it's not worth the effort
link |
01:14:57.020
to increase your hypnotizability at that point.
link |
01:14:59.340
It's worth trying to deal with the problem
link |
01:15:01.100
you're dealing with.
link |
01:15:02.100
So you can get better at using it
link |
01:15:04.420
at the level that you have.
link |
01:15:06.860
There was a study done in which they tried to train people
link |
01:15:09.860
to be more hypnotizable.
link |
01:15:11.100
And obviously there are subjective
link |
01:15:14.300
and behavioral components to the test.
link |
01:15:16.740
You can learn to do a little better on them.
link |
01:15:18.860
But what we found was when we reanalyzed this data,
link |
01:15:22.460
that we could account for three times the final score
link |
01:15:25.580
based on the initial hypnotizability measurement
link |
01:15:28.580
rather than whether or not
link |
01:15:29.820
they had been trained to do better.
link |
01:15:31.180
So you can improve it a little,
link |
01:15:33.060
but it's not worth the trouble.
link |
01:15:34.460
Got it.
link |
01:15:35.420
Along the lines of eyes and eye movements,
link |
01:15:38.100
a lot of interest out there about EMDR,
link |
01:15:40.060
eye movement desensitization reprocessing.
link |
01:15:44.380
Shapiro herself was working,
link |
01:15:46.900
she wasn't at Stanford directly,
link |
01:15:48.140
but was the local to Stanford, I think in Palo Alto.
link |
01:15:52.340
So what are your thoughts on EMDR?
link |
01:15:55.220
Where is it useful?
link |
01:15:56.260
Where do you think it's less useful?
link |
01:15:58.500
Are there things that EMDR could be combined with
link |
01:16:00.780
to make it more useful?
link |
01:16:06.260
The listeners of this podcast come to,
link |
01:16:08.460
I think come to the podcast with a range of backgrounds
link |
01:16:11.660
and interests.
link |
01:16:13.060
To me, it makes sense why EMDR lateralized eye movements
link |
01:16:17.980
might work given the newer data
link |
01:16:19.940
that it can suppress amygdala activity in some animals
link |
01:16:22.740
and animal models and in humans as well.
link |
01:16:25.580
But it really hasn't been explored much neurally.
link |
01:16:27.940
I've heard things like it coordinates
link |
01:16:29.500
the two sides of the brain,
link |
01:16:30.500
which to me is just a throwaway.
link |
01:16:33.300
I don't think there's any evidence
link |
01:16:34.580
that coordinating the two sides of the brain
link |
01:16:36.480
is better than not coordinating.
link |
01:16:38.320
I wouldn't be speaking right now
link |
01:16:39.380
if the two sides of my brain were well correlated
link |
01:16:42.220
because language is lateralized.
link |
01:16:43.820
So I've heard that it mimics rapid eye movements
link |
01:16:46.680
during sleep, but actually it doesn't.
link |
01:16:48.540
So, but I have heard people talk about
link |
01:16:52.620
their positive experiences with EMDR.
link |
01:16:55.220
What are your thoughts about EMDR?
link |
01:16:56.740
Yeah, you had a good comment on that
link |
01:16:58.420
in one of your recent podcasts.
link |
01:16:59.800
And I'll tell you, one way I sort of think about it
link |
01:17:04.860
from a bemused point of view is the old,
link |
01:17:07.860
you mentioned it earlier, the oldest sort of idea
link |
01:17:10.700
of a hypnotic induction was a dangling watch, right?
link |
01:17:14.060
You know, a watch.
link |
01:17:16.320
And in fact, there was enough concern about it
link |
01:17:19.640
that when automobiles were invented,
link |
01:17:21.700
there was a movement to prevent installing windshield wipers
link |
01:17:25.980
because people were afraid that they would be hypnotized
link |
01:17:29.620
if they watched the windshield wipers
link |
01:17:31.420
go back and forth on a car.
link |
01:17:33.620
Now it turns out fortunately that you tend not
link |
01:17:36.420
to look at the windshield wipers.
link |
01:17:37.540
You keep looking through the windshield.
link |
01:17:40.300
And so we have windshield wipers today.
link |
01:17:42.740
But that movement is what exactly
link |
01:17:45.300
used to be a hypnotic induction.
link |
01:17:46.780
I think there is a lot of hypnosis in EMDR.
link |
01:17:50.820
And I think it's a combination of that
link |
01:17:52.940
with exposure-based treatments
link |
01:17:55.780
where you use EMDR to think about it.
link |
01:17:57.780
You tend not to process the experience as much
link |
01:18:01.020
and just do the physical part of it,
link |
01:18:03.140
which I personally think is a drawback.
link |
01:18:05.380
And every study I've seen that was a dismantling study,
link |
01:18:09.420
there's no question that people who go through EMDR,
link |
01:18:11.780
many of them get better with trauma-related problems.
link |
01:18:14.680
And the VA has a big program using it and so on.
link |
01:18:17.480
But every program that has dismantled
link |
01:18:20.620
going through the treatment
link |
01:18:21.840
with having the lateral eye movement
link |
01:18:24.680
has shown that the lateral eye movement
link |
01:18:26.380
doesn't add anything to it.
link |
01:18:27.860
And toward the end of her career,
link |
01:18:29.880
Francine was doing now contralateral touching or something.
link |
01:18:34.460
It wasn't eye movements anymore.
link |
01:18:35.860
It was other things.
link |
01:18:36.700
So I tend to think that EMDR
link |
01:18:42.400
is another form of exposure-based therapy for trauma.
link |
01:18:45.660
But as you've implied,
link |
01:18:47.940
with the exception of this possible new data,
link |
01:18:50.460
it certainly doesn't have to do
link |
01:18:51.940
with rapid eye movement, sleep.
link |
01:18:53.780
And I don't think moving the eyes is the issue.
link |
01:18:56.420
I think it's a way of sitting down and confronting trauma.
link |
01:18:59.500
And I would rather that the trauma itself
link |
01:19:01.600
be processed a bit more than often happens
link |
01:19:04.220
in EMDR.
link |
01:19:05.100
So a lot of people have gotten therapy.
link |
01:19:07.200
Some of them have been helped.
link |
01:19:08.520
Francine used to originally claim
link |
01:19:10.460
that just one session would desensitize people and do it.
link |
01:19:13.340
And that's clearly not true.
link |
01:19:14.940
I see a lot of people who said,
link |
01:19:16.380
yeah, it helped for a while, but I need more.
link |
01:19:18.780
So I think it became a kind of overly simplistic approach
link |
01:19:26.100
to understanding brain physiology, and that part is wrong.
link |
01:19:30.380
And the interesting thing,
link |
01:19:33.020
you mentioned suppressing amygdala activity.
link |
01:19:35.660
It's very interesting.
link |
01:19:37.020
My late friend, Alan Hobson,
link |
01:19:39.420
who was a brilliant sleep researcher,
link |
01:19:40.740
you know Alan, yeah, yeah, yeah.
link |
01:19:42.100
Well, I don't know him,
link |
01:19:42.940
but I read his book when I was in college
link |
01:19:45.020
about the chemistry of sleep
link |
01:19:46.820
and the similarities between dream states and hallucinations.
link |
01:19:51.940
And it's one of the reasons I got into this business.
link |
01:19:54.500
Yes, well, I worked with him
link |
01:19:55.900
in a MacArthur MindBody Network for many years.
link |
01:19:58.260
And he's a brilliant guy,
link |
01:19:59.580
points out that we need to get into primarily
link |
01:20:02.980
a parasympathetic state to go to sleep,
link |
01:20:05.980
that we have to shut off the sympathetic nervous system.
link |
01:20:09.700
And that's why a loud noise wakes you up
link |
01:20:11.580
when your heart rate goes up and all this.
link |
01:20:13.500
So he was brilliant at documenting
link |
01:20:16.500
what happens in the brain of sleep.
link |
01:20:17.700
He pointed out something also very interesting about dreams,
link |
01:20:20.820
which is that the stories in dreams
link |
01:20:23.740
and even the images in dreams
link |
01:20:24.960
can change all over the place in crazy ways,
link |
01:20:27.460
but usually the affect is constant.
link |
01:20:30.380
So usually if it's a frustration dream,
link |
01:20:32.680
whatever happens, you wind up frustrated.
link |
01:20:34.600
And if it's a enjoyment dream,
link |
01:20:36.860
you enjoy whatever's going on.
link |
01:20:38.660
So there's a odd consistency and affect in dreams
link |
01:20:42.220
that you don't have in other states.
link |
01:20:44.980
And the idea of lateral eye movements
link |
01:20:47.900
suppressing amygdala activity would kind of fit with that,
link |
01:20:50.340
that you don't allow intrusions of fear and anger
link |
01:20:54.420
and upset in dreams.
link |
01:20:55.620
It may be there all the time,
link |
01:20:56.980
but it may not be there when you think it should be.
link |
01:20:59.660
So why is it that you can be falling off a building
link |
01:21:02.080
and somehow not that scared?
link |
01:21:03.780
You're just having this experience of flying in a dream.
link |
01:21:06.860
So I think there may be something going on
link |
01:21:10.980
about regulating affect,
link |
01:21:12.220
but we have elaborate and better ways to regulate affect.
link |
01:21:16.700
Great, so EMDR might incorporate some elements of hypnosis.
link |
01:21:21.180
So the lateral eye movements,
link |
01:21:22.900
perhaps by way of suppressing the amygdala,
link |
01:21:24.800
this fear associated center might bring people
link |
01:21:27.060
into a more parasympathetic calm state.
link |
01:21:29.240
So it might be pseudo hypnosis and then exposure therapy
link |
01:21:32.140
through the discussion about the issue.
link |
01:21:34.020
Right. Okay.
link |
01:21:35.700
More research needed on EMDR out there.
link |
01:21:38.400
And obviously something that's come up a lot
link |
01:21:42.720
in this discussion and in our discussions
link |
01:21:45.540
that I have the great fortune of talking to you every week
link |
01:21:48.660
is, and working together,
link |
01:21:50.540
is this idea of getting close to the phobia,
link |
01:21:56.380
getting close to the trauma,
link |
01:21:57.740
re-experiencing it as a portal
link |
01:22:00.100
to then adjusting the response to it
link |
01:22:02.420
and rewiring something so the troubling thing
link |
01:22:05.740
or the horrible thing is no longer as horrible to us.
link |
01:22:09.060
That, but the repeating theme is we can't expect
link |
01:22:14.600
to get over something without getting really close to it,
link |
01:22:17.160
maybe even experiencing it somatically.
link |
01:22:20.940
Nowadays, we hear a lot about triggers and trigger warnings,
link |
01:22:24.740
and certainly one can understand why those are,
link |
01:22:28.460
why those exist, but it seems like there's a,
link |
01:22:31.220
in the general population,
link |
01:22:32.680
there's this idea that we want to move away
link |
01:22:35.100
from anything that upsets us.
link |
01:22:36.440
And yet I think it's fair to say,
link |
01:22:38.220
even though having gathered the statistics that on the whole
link |
01:22:41.620
that the human beings are becoming more and more anxious
link |
01:22:44.460
and more and more stressed, perhaps because of,
link |
01:22:48.860
but certainly in parallel with the fact
link |
01:22:51.640
that we're trying to move away
link |
01:22:52.820
from troubling things, troubling things.
link |
01:22:54.500
So I've heard you say before that it's,
link |
01:22:59.460
in terms of therapeutic approaches,
link |
01:23:01.140
it's not just about the state you get into,
link |
01:23:03.380
but whether or not you brought yourself there voluntarily.
link |
01:23:06.940
That's exactly right.
link |
01:23:07.780
So this element of deliberate self-exposure,
link |
01:23:11.460
deciding I'm going to confront the trauma,
link |
01:23:14.320
I'm going to confront the pain,
link |
01:23:15.980
I'm going to confront the insomnia,
link |
01:23:18.020
I'm going to confront the, you know, and fill in the blank,
link |
01:23:20.800
and then readjusting one's emotional response
link |
01:23:25.720
right up next to that troubling thing.
link |
01:23:28.060
That seems to be the hallmark of this treatment.
link |
01:23:31.260
And if I'm thinking about it correctly,
link |
01:23:34.580
of pretty much all treatments for getting over stuff,
link |
01:23:38.620
if people don't have access
link |
01:23:40.060
to a really good clinician like yourself,
link |
01:23:42.580
how should they carry these thoughts and these ideas?
link |
01:23:45.900
I mean, I think almost everybody of any reasonable age
link |
01:23:49.220
has memories or things that upset them,
link |
01:23:52.260
but we learn to suppress them.
link |
01:23:54.980
What does one do?
link |
01:23:56.820
Obviously the Reverie app has approaches
link |
01:23:58.580
to dealing with some of this inside of the app,
link |
01:24:02.460
but how does one start to think about
link |
01:24:04.260
actually dealing with something like this
link |
01:24:06.680
and avoiding the hazards of just kind of reactivating
link |
01:24:09.380
a lot of painful experiences?
link |
01:24:10.860
Because a lot of being a functional human being
link |
01:24:12.780
is also going to work each day, interacting with people,
link |
01:24:15.420
and not bringing one's trauma, you know,
link |
01:24:17.180
and dumping it out on the table,
link |
01:24:19.100
or being able to just function is so crucial.
link |
01:24:22.780
So how do you think about this as a clinician?
link |
01:24:25.420
Well, you know, the image that comes to mind
link |
01:24:27.420
is the Greek myth of Pandora's box, you know,
link |
01:24:29.460
that it opened and the Furies got out
link |
01:24:31.340
and you couldn't put them back in.
link |
01:24:33.260
And we have this kind of fantasy
link |
01:24:35.060
that once you get into these memories,
link |
01:24:37.580
they'll take you over
link |
01:24:38.420
and you'll never get them back in the box.
link |
01:24:40.540
And I think that's wrong.
link |
01:24:41.940
You know, people who use hypnosis say
link |
01:24:44.660
that there are ways to present things to people
link |
01:24:47.660
that will be helpful in ways that won't.
link |
01:24:49.660
And one real mistake is to tell someone,
link |
01:24:51.760
don't think about purple elephants, you know,
link |
01:24:54.280
what are you thinking about?
link |
01:24:55.180
You know, it doesn't work.
link |
01:24:56.560
So you want to find a way to feel in control of the access
link |
01:25:01.060
and to define what happened on your own terms.
link |
01:25:04.420
And so I'm not a big fan of trigger warnings.
link |
01:25:06.820
I think we're going crazy over, you know,
link |
01:25:09.000
this could be upsetting, that could be upsetting.
link |
01:25:10.740
Yeah, there are lots of things that are upsetting.
link |
01:25:12.320
You know, the average kid has watched 20,000 murders
link |
01:25:16.180
by the time he's 20 years old
link |
01:25:17.680
watching television and movies these days.
link |
01:25:20.240
So, you know, we see terrible things
link |
01:25:22.220
and it's not a matter of,
link |
01:25:24.300
are you exposed to something that's upsetting,
link |
01:25:26.820
but how do you handle it?
link |
01:25:28.060
What do you make of it?
link |
01:25:28.920
And are you feeling in control?
link |
01:25:30.340
It's not like, you know,
link |
01:25:31.820
what Putin is doing to his rival in Russia, you know,
link |
01:25:36.640
forcing him to watch propaganda movies 10 hours a day
link |
01:25:39.340
while he's in prison.
link |
01:25:40.780
It's a matter of thinking about a problem
link |
01:25:46.340
in a way that leaves you feeling you understand it better,
link |
01:25:49.180
you're in more control,
link |
01:25:50.060
you can turn it off when you want,
link |
01:25:52.620
you can turn it on when you want.
link |
01:25:54.260
And so we have to, in life, deal with stressful things.
link |
01:25:57.280
There are studies,
link |
01:25:58.460
Karen Parker at Stanford has done some wonderful studies
link |
01:26:01.980
with primates about stress inoculation,
link |
01:26:04.060
that if you separate a baby monkey from his mother
link |
01:26:07.980
for two hours a day and then reunite them,
link |
01:26:10.420
and then you stress that baby monkey later,
link |
01:26:13.260
they actually handle stress better.
link |
01:26:14.880
There's less cortisol arousal in the face of the stress.
link |
01:26:17.600
Stress inoculation has been called.
link |
01:26:19.360
So mere exposure to trauma or stress,
link |
01:26:23.280
it's a part of living anyway.
link |
01:26:24.860
We can't avoid it even if we'd like to.
link |
01:26:27.140
And it's not pleasant, it's not great,
link |
01:26:30.200
but it's sometimes things you need to learn about life.
link |
01:26:32.680
And if you can find an algorithm for facing it,
link |
01:26:36.420
putting it into perspective, dealing with it,
link |
01:26:38.460
you become a stronger person, not a weaker person.
link |
01:26:40.820
So this idea that college students are such fragile flowers
link |
01:26:44.680
that if you talk about a sexual assault or something,
link |
01:26:47.260
you're doing something terrible to them, it's just wrong.
link |
01:26:50.340
And I think we need to build our ability
link |
01:26:54.460
to recognize and manage stress.
link |
01:26:56.260
And you can't do that without doing it.
link |
01:26:58.020
You can't learn or you can't ride a bicycle
link |
01:27:00.380
without taking the risk of falling off it.
link |
01:27:02.780
And so I think that's the way I think
link |
01:27:05.440
of dealing with stress.
link |
01:27:07.340
Yeah, I really appreciate you saying that.
link |
01:27:10.220
You and I were both at a gathering,
link |
01:27:12.180
let's say where this issue was being discussed
link |
01:27:14.920
and around an issue of a publicized sexual trauma.
link |
01:27:18.700
And you made an excellent case for why
link |
01:27:21.900
this stuff can't be pushed under the rug.
link |
01:27:25.100
And that actually, in my observation,
link |
01:27:27.500
led to a lot of healing for the people that,
link |
01:27:29.380
and the families of people that suffered from this.
link |
01:27:32.620
I do think people are resilient,
link |
01:27:34.500
but we don't really teach how to think about feelings.
link |
01:27:40.140
You know, we're told that we need to feel our feelings,
link |
01:27:43.060
but then again, we are also told that feelings
link |
01:27:45.660
don't hold all the information.
link |
01:27:47.100
And so I think that, as you mentioned,
link |
01:27:48.580
there's no operating or user's manual
link |
01:27:51.220
for this nervous system thing.
link |
01:27:53.340
Brings me to another issue,
link |
01:27:54.540
which is the mind-body connection,
link |
01:27:56.000
something that we're very interested in.
link |
01:27:57.780
And you've done extensive work on.
link |
01:28:01.680
We all like to think that getting more in touch
link |
01:28:03.680
with our body would be a great thing.
link |
01:28:05.520
Learning to intercept, paying attention
link |
01:28:07.220
to our internal landscape would be a great thing.
link |
01:28:09.100
But as we often discuss, when we're feeling lousy,
link |
01:28:13.140
then being really in touch with that lousy feeling
link |
01:28:15.820
may or may not be a good thing, right?
link |
01:28:18.700
So how should we think about mind-body?
link |
01:28:21.380
I can see examples in hypnosis,
link |
01:28:23.860
from your descriptions of hypnosis,
link |
01:28:25.420
where you want to unify the mind-body connection,
link |
01:28:29.880
feel what you're thinking,
link |
01:28:31.740
think what you're feeling, et cetera.
link |
01:28:33.300
But I could also point to elements
link |
01:28:36.100
within the hypnotic process in which you are actively
link |
01:28:39.460
trying to uncouple those.
link |
01:28:41.340
So it sounds to me like this whole mind-body thing
link |
01:28:44.380
is a bit more like a car.
link |
01:28:46.100
You can't say that 40 miles per hour is the optimal speed.
link |
01:28:49.740
It kind of depends on the road you're on
link |
01:28:51.660
and the turn you may or may not be taking.
link |
01:28:53.760
But how should we think about mind-body
link |
01:28:57.440
in terms of navigating daily life?
link |
01:29:00.100
What do you think is the adaptive way
link |
01:29:02.000
to conceptualize the mind-body?
link |
01:29:06.480
It's a big question.
link |
01:29:07.320
It is, it's a very interesting one.
link |
01:29:10.760
I guess I think that it's a matter
link |
01:29:14.800
not of absolute control, but more control,
link |
01:29:18.520
that we need to think of our brain as a tool.
link |
01:29:23.440
And our body signals as tools as well
link |
01:29:26.660
to help us understand what's going on in the world,
link |
01:29:29.960
what we need, what matters, what's important, what isn't.
link |
01:29:33.360
But also something that can be managed,
link |
01:29:36.240
not simply absorbed.
link |
01:29:39.240
And so hypnosis, I think, is a kind of limiting case
link |
01:29:43.520
where you can push it about as far as we can push it
link |
01:29:46.800
in terms of regulating pain.
link |
01:29:48.680
Pain is a good example of that.
link |
01:29:51.680
Obviously, you need to pay attention.
link |
01:29:53.600
If you just broke your ankle,
link |
01:29:54.680
you better pay attention to it and get help,
link |
01:29:56.800
or you're having crushing substernal chest pain.
link |
01:29:59.360
You better do something about it.
link |
01:30:00.840
But our brain is sort of programmed
link |
01:30:03.180
to treat all pain signals as if they were novel pain signals
link |
01:30:06.260
if it's a sudden new problem that needs to be attended to.
link |
01:30:09.600
I teach people to think of the pain and categorize it.
link |
01:30:13.160
See, does the pain mean that if you put weight on this,
link |
01:30:17.880
you're gonna re-injure your ankle, for example,
link |
01:30:20.960
or does it simply mean that your body is healing
link |
01:30:23.040
and the pain is a sign that gradually
link |
01:30:25.420
things are getting back to normal?
link |
01:30:27.200
And so you can modify the way you process pain
link |
01:30:31.720
based on what your brain tells you the pain means.
link |
01:30:35.480
And that's true for emotional pain as well.
link |
01:30:37.720
And particularly where I think a strategy that really helps
link |
01:30:42.040
is if you think of an interpersonal problem
link |
01:30:45.880
or a threat of something coming as an opportunity
link |
01:30:51.180
to do something to ameliorate the situation.
link |
01:30:53.580
So it's not just it's happening to you,
link |
01:30:56.120
but something that you can influence and do something about.
link |
01:30:59.480
So it's blending the receptive with the active response
link |
01:31:04.100
that I think can make a difference.
link |
01:31:05.340
So you try and process it in a way
link |
01:31:06.960
that gives you a deeper understanding of what's happening.
link |
01:31:09.460
You face it, but you also say,
link |
01:31:11.760
this is an opportunity for me to do something about it.
link |
01:31:14.640
And the minute you realistically enhance,
link |
01:31:17.360
and this doesn't mean imagine a way, a heart attack,
link |
01:31:19.900
it means figure out how to rehabilitate from a heart attack
link |
01:31:24.520
or a broken leg or something like that
link |
01:31:27.320
in a way that you get as much control
link |
01:31:30.120
into the situation as you can.
link |
01:31:32.640
I love it.
link |
01:31:34.960
Grief, grief is one of those states
link |
01:31:38.280
that is very hard to remove oneself from.
link |
01:31:42.800
And a lot of people ask me, how do I deal with grief?
link |
01:31:46.240
And I'm not a clinician, so I'm deferring to you.
link |
01:31:49.480
On the one hand, actually someone at Stanford recently
link |
01:31:52.680
came to me and said, my mother passed away
link |
01:31:54.760
and I had a sibling that passed away
link |
01:31:56.100
and they were the only people that I had.
link |
01:31:57.560
And I'm also living alone
link |
01:31:59.160
and I'm challenged with a number of things.
link |
01:32:01.180
And they looked like they were holding it together
link |
01:32:05.320
very well, in fact, given what they were describing.
link |
01:32:08.880
And on the one hand,
link |
01:32:09.940
well, I certainly pointed out that I'm not a clinician,
link |
01:32:13.460
but I said, on the one hand,
link |
01:32:14.820
you could imagine that it would be necessary and useful
link |
01:32:17.580
to go into the grief state
link |
01:32:19.020
if you want to transition through it.
link |
01:32:22.660
On the other hand, I've heard before
link |
01:32:25.580
that the cathartic model of just really diving
link |
01:32:29.380
into an emotion can also be potentially hazardous
link |
01:32:32.780
if you don't have any anchors to grab onto.
link |
01:32:37.780
What is the view of psychiatry or your view of grief
link |
01:32:41.720
and how to deal with grief?
link |
01:32:43.040
Because I think grief is one of those
link |
01:32:45.280
all-encompassing emotions for many people.
link |
01:32:48.540
It is, and it's a very important,
link |
01:32:50.640
natural, necessary stage of life.
link |
01:32:52.640
And the reason we have all these grief rituals
link |
01:32:55.120
from burials and memorials and headstones
link |
01:32:59.380
and sitting Shiva and other things that people do,
link |
01:33:02.180
it's a way of making it real,
link |
01:33:04.440
that an incomprehensible loss has to be comprehended.
link |
01:33:08.140
You have to realize that you're now gonna have to live life
link |
01:33:10.880
without your loved one, your parent, your sibling, whoever.
link |
01:33:15.400
And we've all gone through this at one time or another.
link |
01:33:18.300
I certainly have.
link |
01:33:19.720
And it's very hard to just come to terms with,
link |
01:33:22.880
but one principle is to sort of say,
link |
01:33:26.240
it's never all or none, it's more or less.
link |
01:33:29.520
So yes, it's all or none that you've lost a loved one.
link |
01:33:33.000
But I ask people as part of their grieving
link |
01:33:35.860
to say to themselves,
link |
01:33:37.400
and I do this in hypnosis sometimes too,
link |
01:33:41.440
you've lost them, but what have they left you with?
link |
01:33:44.080
What have they bequeathed to you even though they're gone?
link |
01:33:47.280
And I'll sometimes ask them to say,
link |
01:33:49.300
if your mother could be here right now,
link |
01:33:51.560
what would she say to you?
link |
01:33:53.320
How would she feel about your life now?
link |
01:33:55.040
What would she advise you to do?
link |
01:33:57.000
So in our support groups for women
link |
01:33:59.240
with advanced breast cancer, we lost people.
link |
01:34:02.240
And I gotta tell you that we were warned by oncologists
link |
01:34:04.840
that we demoralize people that,
link |
01:34:06.920
I mean, they were wonderful oncologists,
link |
01:34:08.340
but there were some that were very afraid
link |
01:34:09.980
that we would harm them in some way
link |
01:34:13.040
because the mortality rate is fairly high
link |
01:34:16.600
with metastatic breast cancer.
link |
01:34:18.280
They're gonna watch people die of the same disease
link |
01:34:21.140
and you'll demoralize them.
link |
01:34:23.080
So we actually measured their emotion
link |
01:34:25.920
and the content of speech every five minutes
link |
01:34:28.220
throughout a bunch of groups
link |
01:34:29.340
to make sure that wasn't happening.
link |
01:34:30.560
What we found was that they talked about more serious issues
link |
01:34:33.780
but the mood didn't actually get worse.
link |
01:34:35.860
And we found in general that expressing negative emotion
link |
01:34:39.000
on the long run helps people be less anxious
link |
01:34:41.200
and depressed over time.
link |
01:34:42.160
And we've shown this in randomized clinical trials,
link |
01:34:44.360
so it's not just my clinical impression.
link |
01:34:47.200
And what we try to get them to do is to face a loss,
link |
01:34:54.680
live with the emotion that comes with it,
link |
01:34:56.240
but also see that the reason it hurts so much
link |
01:34:58.840
is how much that person gave you.
link |
01:35:00.520
So we would do a self-hypnosis exercise
link |
01:35:03.100
at the end of the group and say,
link |
01:35:03.940
I want you to get your body floating safe and comfortable.
link |
01:35:06.980
Now picture Mary and sit with the feeling of sadness
link |
01:35:11.520
that she's no longer with us.
link |
01:35:13.440
And we do that for a few minutes.
link |
01:35:14.960
And then we'd say on the other side,
link |
01:35:16.760
picture one thing she left with you that you still have
link |
01:35:19.640
that you carry on in your heart
link |
01:35:21.800
her tradition of what she gave to you.
link |
01:35:24.520
And so just seeing it not as a complete loss,
link |
01:35:28.120
but as a real loss, a painful loss,
link |
01:35:30.780
but one that helps you to reflect on what you gained
link |
01:35:33.560
from her and knowing her,
link |
01:35:35.720
I think can be very helpful in the grieving process.
link |
01:35:38.600
That's very helpful, a way to conceptualize it.
link |
01:35:41.800
A couple of quick questions.
link |
01:35:44.720
Can children be safely hypnotized or do self-hypnosis?
link |
01:35:50.200
It's sometimes harder for them to do self-hypnosis.
link |
01:35:52.880
They need more structure to do it.
link |
01:35:54.600
You've gotta share your dorsolateral prefrontal cortex
link |
01:35:58.400
with them a little bit.
link |
01:35:59.700
But yes, absolutely, children can be very hypnotizable.
link |
01:36:03.000
And I know pediatricians who use it wonderfully all the time
link |
01:36:08.200
they get them to focus on something else.
link |
01:36:10.800
So they're gonna have to give them a shot
link |
01:36:12.600
or draw blood or something.
link |
01:36:14.000
And they'll say, I'm gonna press your happy button
link |
01:36:18.400
and presses their belly button
link |
01:36:20.040
and they start to giggle the way kids do.
link |
01:36:21.840
And meanwhile, the nurses drawing the blood
link |
01:36:24.440
and they don't even notice it.
link |
01:36:26.220
Dentists, good dentists can use it
link |
01:36:28.160
to help kids with fear and pain.
link |
01:36:30.380
So yes, it can be very effective for children.
link |
01:36:32.720
We did a randomized trial.
link |
01:36:34.040
I have a publication in pediatrics.
link |
01:36:36.000
My late sister who was a pediatrician
link |
01:36:38.840
and who always used to joke that she was the only one
link |
01:36:41.640
in our family who was a real doctor.
link |
01:36:44.640
I said, I got you, I got a paper in pediatrics.
link |
01:36:47.920
And the paper was children having to undergo
link |
01:36:51.480
avoiding cystourethrograms.
link |
01:36:53.120
So the anatomy of the kidney, if you'll forgive me,
link |
01:36:56.880
is sort of interesting in that the ureter
link |
01:37:00.000
that goes into the bladder
link |
01:37:01.680
normally goes into the bladder at an angle.
link |
01:37:04.120
And so that means that when the bladder contracts
link |
01:37:06.800
to expel urine, it automatically closes off the ureter
link |
01:37:10.800
because it's sideways to the bladder.
link |
01:37:12.820
Some kids are born with it perpendicular
link |
01:37:14.880
and then you'll get reflux into the kidney.
link |
01:37:17.160
And some children outgrow it.
link |
01:37:19.260
Some need pretty complicated surgery to fix that.
link |
01:37:22.640
And so you image them every year or so
link |
01:37:26.000
to see whether they're getting kidney damage or not.
link |
01:37:28.640
And it's a pretty miserable experience.
link |
01:37:30.440
You're a nine-year-old girl.
link |
01:37:32.000
You have to go and lie on a hard, cold table,
link |
01:37:33.880
have strangers pull your legs apart
link |
01:37:35.600
and stick a catheter into your urethra
link |
01:37:38.480
and hold in the bladder and then expel urine.
link |
01:37:41.640
And so you get into these struggling fights.
link |
01:37:43.800
And of course, the more they struggle,
link |
01:37:45.120
the more they constrict and it makes it harder to do it.
link |
01:37:47.540
So I was asked if we could test it.
link |
01:37:51.000
So we did a randomized trial at Children's Hospital.
link |
01:37:54.080
They either got training in self-hypnosis.
link |
01:37:56.240
I would meet with them and the mother the week before.
link |
01:37:59.200
We find out from the kids where they like to be.
link |
01:38:01.440
And I'd say, you're gonna play a trick on your doctors.
link |
01:38:03.740
Your body's there.
link |
01:38:04.580
You're somewhere else.
link |
01:38:05.580
Go visit your friend.
link |
01:38:06.680
Go to Disneyland.
link |
01:38:07.520
Do something else.
link |
01:38:08.340
And the mother would work on this with me
link |
01:38:10.060
at the head of the table.
link |
01:38:11.600
And we found that these children were much easier to image.
link |
01:38:15.280
One got so relaxed that, so your guy would,
link |
01:38:17.380
he said, normally it takes us 10 minutes
link |
01:38:18.920
to get them to pee after they're doing this.
link |
01:38:21.160
She was so relaxed, she started peeing
link |
01:38:22.780
before I could even get the bedpan under her
link |
01:38:25.100
and I had to clean up the table, you know.
link |
01:38:27.200
And they also, 17 minutes shorter procedures.
link |
01:38:30.400
And that's a long 17 minutes for a little kid.
link |
01:38:33.820
So it can be very effective with children.
link |
01:38:36.560
They're less anxious.
link |
01:38:37.440
They have less pain
link |
01:38:38.480
and get through these difficult procedures very well.
link |
01:38:42.360
That's great.
link |
01:38:43.600
Has hypnosis ever been done for couples,
link |
01:38:46.480
like couples therapy?
link |
01:38:47.560
I'm thinking of pretty much every clinical setting here.
link |
01:38:49.860
Both people have to be hypnotizable, of course.
link |
01:38:52.460
But the reason I ask about this is next,
link |
01:38:54.680
I'm going to ask about psychedelics.
link |
01:38:56.480
And there's a lot of interest in coordinating states
link |
01:38:59.620
through the use of drugs of different kinds.
link |
01:39:04.040
We actually do this when we treat depression, right?
link |
01:39:05.840
You have a depressed person with a family members
link |
01:39:08.360
who are not depressed and you say, well,
link |
01:39:09.600
let's make them all not depressed, right?
link |
01:39:13.080
I mean, but in all, and I'm only half kidding there
link |
01:39:15.960
because that is kind of the underlying logic in some sense,
link |
01:39:18.480
but are you aware of any coordinated hypnosis?
link |
01:39:23.720
That's interesting.
link |
01:39:25.000
I've done plenty of it in groups, not with couples.
link |
01:39:27.880
You can hypnotize large groups at once?
link |
01:39:29.880
Yeah, yeah.
link |
01:39:30.720
Are we hypnotized right now?
link |
01:39:31.540
Yeah, you are.
link |
01:39:32.380
I hope you've been enjoying it.
link |
01:39:36.680
But the metastatic breast cancer,
link |
01:39:39.040
and there was a group of like 10 women
link |
01:39:40.580
who would meet once a week
link |
01:39:41.640
and we would all go into hypnosis together.
link |
01:39:44.440
I didn't realize that you were hypnotizing them
link |
01:39:46.560
collectively.
link |
01:39:47.400
Yes, yes, right.
link |
01:39:48.820
Fascinating.
link |
01:39:49.660
And that, you know, if anything,
link |
01:39:51.180
I think it brings out the best in people's abilities
link |
01:39:53.640
because it's a shared social experience
link |
01:39:55.700
and they would talk about it afterwards.
link |
01:39:59.240
And so, yes, that's absolutely doable, yeah.
link |
01:40:02.500
And I don't want to focus on psychedelics specifically,
link |
01:40:05.160
maybe that's a topic for a future episode,
link |
01:40:06.880
but is there any basis for combining hypnosis
link |
01:40:10.680
with drug therapies inside of the hypnotic episode?
link |
01:40:15.480
So I realize that some patients of yours
link |
01:40:17.260
might be prescribed a antidepressant
link |
01:40:19.860
or a medication for some purpose,
link |
01:40:23.340
maybe same or different than the hypnosis
link |
01:40:25.040
is being directed toward,
link |
01:40:26.520
but is there any evidence that if people are relaxed
link |
01:40:30.880
through the use of a Propranolol or some, you know,
link |
01:40:34.180
one of these many things in the psychiatrist's kit,
link |
01:40:37.200
that hypnosis can be more effective?
link |
01:40:40.160
Well, interestingly, one study that I haven't mentioned
link |
01:40:44.040
is we did spectroscopy on people who were hypnotized
link |
01:40:50.120
and we found that there was a correlation
link |
01:40:53.360
between hypnotizability and GABA activity
link |
01:40:57.600
in the anterior cingulate cortex,
link |
01:40:59.960
which fits with turning down activity.
link |
01:41:02.480
So to the extent that we can self-medicate
link |
01:41:05.040
and GABA receptors basically are doing
link |
01:41:07.520
what benzodiazepines do to the brain,
link |
01:41:10.480
that can happen when people are hypnotized.
link |
01:41:13.040
So you're saying inside of the hypnosis,
link |
01:41:14.960
you have neural evidence that there's a kind of
link |
01:41:18.120
a sedative effect of hypnosis at the chemical level?
link |
01:41:22.080
Yeah, right, right.
link |
01:41:23.320
The people who are more hypnotizable
link |
01:41:24.680
have more of those GABA receptors
link |
01:41:26.520
and it's related to the degree of their hypnotizability.
link |
01:41:30.560
In terms of, there have been studies
link |
01:41:32.380
where they try to give people medications as well.
link |
01:41:35.200
And the interesting thing with benzodiazepines,
link |
01:41:37.720
which activate inhibitory activity in the brain,
link |
01:41:42.520
if you're very anxious,
link |
01:41:44.360
it might improve your hypnotic response a bit
link |
01:41:46.360
if you're just so anxious and you can't do it.
link |
01:41:48.560
If you're not very anxious,
link |
01:41:49.720
it actually inhibits hypnotic activity
link |
01:41:52.080
because you get sort of sedated and just out of it
link |
01:41:54.360
and you can't focus your attention as well.
link |
01:41:56.720
So by and large, we don't use drugs
link |
01:42:01.360
as an adjuvant to hypnotic experience.
link |
01:42:04.000
Most of the time you don't need to
link |
01:42:05.320
and sometimes it can make it worse rather than better.
link |
01:42:09.560
There's some evidence that mild stimulants
link |
01:42:12.320
might enhance hypnotic responsiveness a little reliably,
link |
01:42:15.320
but too much will again scatter attention
link |
01:42:17.820
and you'll have less control over it.
link |
01:42:19.520
So they might be adjuvants,
link |
01:42:22.560
but I frankly think hypnosis is more of a replacement
link |
01:42:25.700
than a need of supplementation.
link |
01:42:28.600
Your laboratory, my laboratory have,
link |
01:42:30.900
well, sort of snuck into your lab
link |
01:42:34.420
and then trying to kind of merge the two.
link |
01:42:36.300
It's been a lot of fun and learning a lot
link |
01:42:39.180
about the power of respiration of breathing
link |
01:42:42.140
to shift brain states, not just during breathing protocols,
link |
01:42:45.500
but at all times.
link |
01:42:47.060
And we will do an entire episode about those protocols,
link |
01:42:49.660
I think after those are published and so on.
link |
01:42:54.560
But breathing itself is,
link |
01:42:58.100
you've described as a bridge between conscious
link |
01:42:59.980
and unconscious states.
link |
01:43:01.460
And so I have to ask how important
link |
01:43:05.540
is the patient's breathing pattern?
link |
01:43:08.020
How closely are you monitoring their breathing pattern?
link |
01:43:11.220
How closely do you monitor your own breathing pattern
link |
01:43:13.600
as you're inducing hypnosis?
link |
01:43:15.460
Put simply, what is the role of respiration
link |
01:43:17.820
in shifting the brain's state during a hypnotic protocol?
link |
01:43:23.580
Yeah, that's very interesting.
link |
01:43:24.580
You had a great show with Jack Feldman.
link |
01:43:26.780
Jack Feldman, and he is.
link |
01:43:30.220
And the issue, I watch it, I try,
link |
01:43:37.860
the work that we're enjoying doing together
link |
01:43:40.320
shows that there are breathing patterns
link |
01:43:41.900
that may increase sympathetic arousal or may decrease.
link |
01:43:46.460
It may help in cyclic sighing,
link |
01:43:49.280
seems to actually where you have more time spent
link |
01:43:51.500
exhaling than inhaling.
link |
01:43:53.500
And there's reason to believe that it induces
link |
01:43:56.700
parasympathetic activity,
link |
01:43:58.220
because you're increasing pressure in the chest.
link |
01:44:00.720
And therefore, allowing the heart to slow down
link |
01:44:04.420
because blood is being returned to the atrium more easily.
link |
01:44:09.580
I do use it, I ask people to take a deep breath
link |
01:44:12.620
as part of the induction and then slowly exhale.
link |
01:44:15.080
And partly as a result of our research together,
link |
01:44:17.240
I'm emphasizing this slow exhale more
link |
01:44:19.580
as part of, to enhance the idea in the induction
link |
01:44:23.860
that this is a period of relaxation,
link |
01:44:25.620
because I think they are inducing that
link |
01:44:28.260
and perhaps perceiving it as well.
link |
01:44:30.940
So there's no, you're absolutely right
link |
01:44:34.220
that breathing is very interesting
link |
01:44:36.660
because it's right at the edge of conscious,
link |
01:44:38.300
and Jack talked about that too,
link |
01:44:39.700
of conscious and unconscious control,
link |
01:44:41.360
that it will go on automatically, but we can control it.
link |
01:44:44.900
And so it's a kind of way for us to demonstrate
link |
01:44:47.320
to ourselves greater ways of modulating our internal state.
link |
01:44:54.260
So you can either do it thinking about it
link |
01:44:56.340
the way we do with pain control and hypnosis,
link |
01:44:58.940
or you can do it to some extent
link |
01:45:00.460
by taking charge of your breathing
link |
01:45:03.660
and doing things that will produce a change
link |
01:45:05.960
that you want to see happen in your body.
link |
01:45:08.060
So I like it because it's right at that margin
link |
01:45:11.020
where you can enhance, for me,
link |
01:45:14.100
I like that as a way of augmenting hypnosis
link |
01:45:16.540
more than medication.
link |
01:45:17.740
I think this is a powerful way of doing that.
link |
01:45:20.740
Great, I'm really excited to see where all of this goes.
link |
01:45:23.600
Breathing, vision, bodily states, clearly the,
link |
01:45:28.020
and directed mental focus
link |
01:45:32.500
seem to be the key elements of hypnosis.
link |
01:45:34.980
Am I missing any other ingredients?
link |
01:45:38.140
Yeah, I think that's right.
link |
01:45:39.900
Breathing, vision.
link |
01:45:40.940
Breathing, vision, how you change your vision.
link |
01:45:43.540
And you don't, typically you're in a physically relaxed state
link |
01:45:49.540
but frankly there are people at the peak of performance
link |
01:45:52.860
including physical, athletic performance
link |
01:45:54.980
or musical performance
link |
01:45:56.640
when they're in hypnotic states too.
link |
01:45:58.540
I've talked to classical pianists who say,
link |
01:46:01.060
I'm not thinking, if I start thinking
link |
01:46:02.340
about what my fingers are doing now, I screw up.
link |
01:46:04.740
I'm floating above the piano thinking about the tone
link |
01:46:08.300
that I want to feel exuding from the instrument.
link |
01:46:11.520
So that's a hypnotic like state too.
link |
01:46:13.540
And many athletes who are in peak performance
link |
01:46:18.220
are just flowing with it.
link |
01:46:20.100
They're not thinking step by step, what am I doing?
link |
01:46:24.300
And that's when you're doing your best.
link |
01:46:26.020
Or when we're working or giving a talk and doing it well,
link |
01:46:33.020
we're in a hypnotic like state.
link |
01:46:34.740
So it usually requires,
link |
01:46:39.700
but doesn't necessarily require physical comfort
link |
01:46:42.220
or quietness.
link |
01:46:43.260
It can sometimes be intense activity.
link |
01:46:45.980
Incredible.
link |
01:46:47.280
Well, this has been an amazing discussion.
link |
01:46:50.660
I've learned so much as I always do from you.
link |
01:46:54.060
Where can people learn more
link |
01:46:56.060
about how they can get hypnotized?
link |
01:46:58.860
We mentioned Reveri, we will put a link to it.
link |
01:47:00.660
It's R-E-V-E-R-I.com is the way to access that.
link |
01:47:05.300
Or it's the Reveri app from the app store is the other way.
link |
01:47:07.860
Reveri.com is the website, you can get to it through that
link |
01:47:10.560
or download the Reveri app from the app store.
link |
01:47:13.840
Great.
link |
01:47:15.740
So currently on Apple, hopefully soon, also on Android.
link |
01:47:18.840
But in the meantime,
link |
01:47:21.300
what if people are interested in exploring clinical hypnosis
link |
01:47:24.260
working with you or somebody similar?
link |
01:47:27.220
Is there a centralized resource that people can go to
link |
01:47:29.740
to find really well-trained hypnotists?
link |
01:47:34.220
There are two good professional organizations
link |
01:47:37.820
that will help you with that.
link |
01:47:38.700
One is the Society for Clinical and Experimental Hypnosis.
link |
01:47:42.540
And I think that's S-C-E-H dot U-S is their website.
link |
01:47:46.940
We'll look it up and provide a link.
link |
01:47:48.140
And the American Society for Clinical Hypnosis.
link |
01:47:50.340
And they both provide referral services for professionals.
link |
01:47:55.500
You can look it up.
link |
01:47:56.560
I would just say in general,
link |
01:47:58.060
look for someone who is licensed and trained
link |
01:48:00.820
in their primary professional discipline,
link |
01:48:02.740
psychiatry, psychology, medicine, dentistry,
link |
01:48:06.140
and who has training and interest in using hypnosis
link |
01:48:09.660
is a way to do it.
link |
01:48:11.140
Great.
link |
01:48:11.980
And then one more question, and then a comment.
link |
01:48:15.140
The question is, will you be my psychiatrist?
link |
01:48:17.300
I'm honored, I'm honored.
link |
01:48:20.380
It's a tall task.
link |
01:48:22.180
I might be the most stubborn patient.
link |
01:48:24.460
I think the hardest work's already been done, Andrew.
link |
01:48:26.540
Thank you.
link |
01:48:27.380
You're fine now.
link |
01:48:28.220
I appreciate that.
link |
01:48:29.040
Well, and the final thing is a comment.
link |
01:48:31.820
First of all, thank you so much for being here today,
link |
01:48:35.140
for sharing your knowledge.
link |
01:48:36.380
I hope we can do it again and again.
link |
01:48:38.840
I hope so.
link |
01:48:39.680
I love working with your laboratory and with you.
link |
01:48:41.740
Likewise.
link |
01:48:42.580
Because when you speak, I learn,
link |
01:48:44.600
and I know others do as well.
link |
01:48:47.860
We will put resources to get to you.
link |
01:48:49.940
But I also just want to say thank you
link |
01:48:51.980
for doing the work that you do.
link |
01:48:54.580
It's an incredible thing that in this world
link |
01:48:57.580
where we are discovering so much about how the body works,
link |
01:49:00.480
the mind is still rather mysterious
link |
01:49:02.720
and people are struggling with a lot of things.
link |
01:49:04.480
But also I think people are really excited
link |
01:49:05.860
about applying tools like hypnosis to perform better,
link |
01:49:10.200
feel better mentally and physically.
link |
01:49:11.660
And so you've pointed us to a tremendous amount of resources
link |
01:49:15.060
and how these tools work
link |
01:49:17.540
and where they've already been demonstrated to work.
link |
01:49:19.500
So just thank you.
link |
01:49:20.940
I know this is your life's professional commitment in life
link |
01:49:25.060
and we all benefit.
link |
01:49:26.460
So thank you so much.
link |
01:49:27.300
Well, thank you.
link |
01:49:28.120
But it's been a real joy for me
link |
01:49:28.960
to be collaborating with you
link |
01:49:30.300
and for you to be using your precision and knowledge
link |
01:49:33.080
about neuroanatomy, neurobiology to address problems
link |
01:49:37.380
that often people who are that disciplined
link |
01:49:39.300
in the primary neurobiological end
link |
01:49:42.180
aren't as interested in as you are.
link |
01:49:43.900
And so it's really been a pleasure to try
link |
01:49:45.820
and bring together what we both know
link |
01:49:48.780
from these different perspectives
link |
01:49:50.320
to build something that neither of us could do alone.
link |
01:49:53.540
And so it's been a real joy for me to do it.
link |
01:49:56.100
Thank you.
link |
01:49:56.940
I'm honored.
link |
01:49:57.760
Thank you.
link |
01:49:58.600
Thank you very much, David.
link |
01:49:59.440
You're welcome.
link |
01:50:00.580
Thank you for joining me today
link |
01:50:01.700
for my discussion with Dr. David Spiegel.
link |
01:50:04.020
I hope you found it as fascinating as I did.
link |
01:50:06.860
And if you'd like to see the video
link |
01:50:08.300
of Dr. Spiegel hypnotizing me
link |
01:50:10.500
in what constitutes a abbreviated clinical hypnosis session,
link |
01:50:14.140
you can go to the Huberman Lab Clips channel on YouTube.
link |
01:50:17.580
Also, if you'd like to check out the Reverie app
link |
01:50:19.540
for self-hypnosis designed by Dr. Spiegel and colleagues,
link |
01:50:22.620
you can go to Reverie, that's R-E-V-E-R-I.com
link |
01:50:26.440
to see the Reverie app.
link |
01:50:27.620
There's also other information there
link |
01:50:28.980
about the scientific studies that support the Reverie app.
link |
01:50:31.780
If you're enjoying and or learning from this podcast,
link |
01:50:34.200
please subscribe to our YouTube channel.
link |
01:50:35.880
That's a terrific zero cost way to support us.
link |
01:50:38.620
In addition, please subscribe to the podcast
link |
01:50:40.940
on Apple and or Spotify.
link |
01:50:42.660
And on Apple, you have the opportunity
link |
01:50:44.640
to leave us up to a five-star review.
link |
01:50:46.900
Please also leave us comments and feedback
link |
01:50:48.860
as well as suggestions for guests
link |
01:50:50.300
that you'd like us to host on the Huberman Lab podcast
link |
01:50:52.700
in the comment section on our YouTube channel.
link |
01:50:55.180
Please also check out the sponsors
link |
01:50:56.580
mentioned at the beginning of today's episode.
link |
01:50:58.540
That's the best way to support this podcast.
link |
01:51:01.040
We also have a Patreon,
link |
01:51:02.260
that's patreon.com slash Andrew Huberman,
link |
01:51:05.020
and there you can support the podcast
link |
01:51:06.900
at any level that you like.
link |
01:51:08.500
On many previous episodes of the Huberman Lab podcast,
link |
01:51:10.820
we discussed supplements.
link |
01:51:12.140
While supplements aren't necessary for everybody,
link |
01:51:13.960
many people derive tremendous benefit from them
link |
01:51:16.200
for things like enhancing sleep and focus
link |
01:51:18.460
and various other aspects
link |
01:51:19.780
of brain and body health and performance.
link |
01:51:22.000
One issue with supplements, however,
link |
01:51:23.380
is that many of the supplements out there
link |
01:51:25.400
simply do not contain what's listed on the bottle
link |
01:51:28.140
and or the quality of the ingredients is not very high.
link |
01:51:31.900
That's why we partnered with Thorne supplements.
link |
01:51:34.140
Thorne supplements are used by all the major sports teams
link |
01:51:36.740
and they partnered with the Mayo Clinic.
link |
01:51:38.860
The reason they have so many high-level partners
link |
01:51:41.060
is that Thorne supplements
link |
01:51:42.340
are of the very highest quality ingredients.
link |
01:51:44.740
They also are extremely precise
link |
01:51:46.820
in terms of what's listed on the bottle
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01:51:48.780
is always what's in the bottle.
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01:51:50.540
If you'd like to see the Thorne supplements that I take,
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01:51:52.640
you can go to Thorne, that's thorne.com
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01:51:55.740
slash the letter U slash Huberman,
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01:51:57.820
and there you can see the Thorne supplements that I take
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01:52:00.140
and get 20% off any of those supplements.
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01:52:02.620
Also, if you navigate deeper into the Thorne site
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01:52:04.860
through that portal, thorne.com
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01:52:07.580
slash the letter U slash Huberman,
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01:52:09.860
you can also get 20% off any of the other supplements
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01:52:12.580
that Thorne makes.
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01:52:13.940
If you're not already following us on Instagram and Twitter,
link |
01:52:16.480
please do so.
link |
01:52:17.320
It's Huberman Lab on both Instagram and Twitter,
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01:52:19.380
and at those channels,
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01:52:20.820
I cover science and science-related tools,
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01:52:22.700
some of which overlap with the content of this podcast,
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01:52:26.020
other of which does not and is unique content.
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01:52:28.680
So once again, thank you for joining me
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01:52:30.220
for my discussion with Dr. David Spiegel,
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01:52:32.260
and last, but certainly not least,
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01:52:34.460
thank you for your interest in science.
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01:52:36.220
I'll see you in the next one.