back to index

Using Failures, Movement & Balance to Learn Faster | Huberman Lab Podcast #7



link |
00:00:00.000
Welcome to the Huberman Lab Podcast,
link |
00:00:02.260
where we discuss science and science-based tools
link |
00:00:04.900
for everyday life.
link |
00:00:09.620
My name is Andrew Huberman,
link |
00:00:10.780
and I'm a professor of neurobiology and ophthalmology
link |
00:00:13.540
at Stanford School of Medicine.
link |
00:00:15.380
This podcast is separate
link |
00:00:16.500
from my teaching and research roles at Stanford.
link |
00:00:18.860
It is, however, part of my desire and effort
link |
00:00:20.820
to bring you zero cost to consumer information
link |
00:00:22.940
about science and science-related tools.
link |
00:00:25.860
In keeping with that theme,
link |
00:00:26.940
I'd like to thank the sponsors of today's podcast.
link |
00:00:29.740
Our first sponsor is Headspace.
link |
00:00:32.460
Headspace is a meditation app that makes meditation easy.
link |
00:00:35.860
I've been meditating on and off now for about 30 years,
link |
00:00:39.020
although I confess more off than on.
link |
00:00:41.560
And that's because I think like for a lot of people,
link |
00:00:44.220
sticking to a meditation practice can be pretty challenging.
link |
00:00:47.600
I started using Headspace a few years ago,
link |
00:00:49.900
and I found that it's really allowed me
link |
00:00:51.660
to stick to a meditation practice on a regular basis.
link |
00:00:54.460
I meditate anywhere from five to seven times a week.
link |
00:00:57.660
The app includes meditations that are all backed
link |
00:01:00.600
by scientific peer-reviewed studies,
link |
00:01:02.980
and it makes it really easy to start
link |
00:01:04.980
and complete the meditations.
link |
00:01:06.660
I started using these meditations
link |
00:01:08.060
while I was flying a few years back.
link |
00:01:10.380
On JetBlue flights,
link |
00:01:11.300
they started offering Headspace meditation,
link |
00:01:12.940
so that's where I initially started,
link |
00:01:14.300
and then I moved over to the app, and I really enjoy it,
link |
00:01:17.100
and I derive great benefit from it.
link |
00:01:19.220
If you'd like to try Headspace,
link |
00:01:20.740
you can go to headspace.com slash special offer,
link |
00:01:24.140
and if you do that, you'll get all the meditations
link |
00:01:26.460
that Headspace offers for free for one month.
link |
00:01:28.980
That's headspace.com slash special offer.
link |
00:01:32.140
You get all the meditations for free,
link |
00:01:33.500
which is the best offer that Headspace has
link |
00:01:35.860
available right now,
link |
00:01:37.220
so if you're interested in it, check it out.
link |
00:01:39.380
The second sponsor of today's podcast is Athletic Greens.
link |
00:01:42.620
Athletic Greens is an all-in-one
link |
00:01:44.380
vitamin mineral probiotic drink.
link |
00:01:47.060
I started using Athletic Greens in 2012,
link |
00:01:50.100
and I've been using it continuously ever since.
link |
00:01:52.800
I started using Athletic Greens
link |
00:01:54.420
because I found it rather dizzying to know
link |
00:01:56.500
which vitamins and minerals to take,
link |
00:01:58.660
and Athletic Greens allows me to get
link |
00:02:00.700
the full base of all the necessary vitamins and minerals
link |
00:02:03.220
in one easy-to-consume drink.
link |
00:02:05.640
It also turns out that the drink tastes quite good.
link |
00:02:07.980
I mix mine with some lemon juice and some water.
link |
00:02:10.260
I'll drink it once or twice a day.
link |
00:02:12.380
The probiotics in Athletic Greens are also important to me
link |
00:02:15.140
because there are a lot of data now
link |
00:02:16.500
supporting the fact that the gut microbiome
link |
00:02:19.540
is important for the gut-brain axis,
link |
00:02:21.560
for various aspects of cognitive function, immune function,
link |
00:02:24.500
metabolic function.
link |
00:02:26.020
There's just a huge number of things
link |
00:02:27.400
that having a healthy gut microbiome
link |
00:02:29.140
has been shown to be important for,
link |
00:02:30.580
so by taking Athletic Greens,
link |
00:02:32.300
I have that base covered as well.
link |
00:02:34.820
If you'd like to try Athletic Greens,
link |
00:02:36.360
you can go to athleticgreens.com slash Huberman,
link |
00:02:39.660
and if you do that, they'll give you a year's supply
link |
00:02:42.100
of liquid vitamin D3K2.
link |
00:02:44.880
There are also a lot of data now showing
link |
00:02:46.340
that vitamin D3 is very important
link |
00:02:48.440
for a number of different biological functions.
link |
00:02:51.240
In addition, they'll give you five free travel packs
link |
00:02:54.460
with your order.
link |
00:02:55.660
It can be difficult to mix up powders while on the road,
link |
00:02:58.460
you know, when in a car or, you know,
link |
00:03:00.540
in a hotel or on a plane, et cetera.
link |
00:03:03.180
The travel packs make everything really clean and easy,
link |
00:03:05.620
so you'll get the year supply of vitamin D3K2
link |
00:03:08.420
plus the five free travel packs
link |
00:03:09.940
if you go to athleticgreens.com slash Huberman.
link |
00:03:13.680
The third sponsor of today's podcast is Made For.
link |
00:03:16.500
Made For is a behavioral science company
link |
00:03:18.160
that makes learning positive habits and growth mindset easy.
link |
00:03:21.740
I've been involved with Made For since the beginning
link |
00:03:24.380
as the lead of their scientific advisory.
link |
00:03:27.100
Other members of the scientific advisory include,
link |
00:03:28.980
for instance, the head of the Chronobiology Unit
link |
00:03:31.060
at the National Institutes of Mental Health,
link |
00:03:33.180
as well as psychiatrists from Harvard Medical School
link |
00:03:35.620
and elsewhere, all of whom are serious about science
link |
00:03:38.080
and science-related tools for developing positive habits
link |
00:03:40.660
and growth mindset.
link |
00:03:42.500
The program is a 10-month program
link |
00:03:44.580
during which each month you engage in a specific activity
link |
00:03:47.980
designed to encourage and cultivate
link |
00:03:50.860
positive habits and growth mindset.
link |
00:03:53.220
As well, we hold a monthly Zoom call
link |
00:03:55.180
during which we discuss the program,
link |
00:03:57.060
people's progress, and answer any questions
link |
00:03:58.860
they have directly.
link |
00:04:00.140
If you'd like to try Made For,
link |
00:04:01.900
you can go to getmadefor.com,
link |
00:04:04.460
and if you put Huberman in at checkout,
link |
00:04:06.300
you'll get 20% off the program.
link |
00:04:07.980
That's getmadefor.com.
link |
00:04:09.580
Put Huberman in at checkout and get 20% off the program.
link |
00:04:13.680
Today, we're going to talk about
link |
00:04:14.860
how to change your nervous system for the better.
link |
00:04:18.000
As you recall, your nervous system
link |
00:04:19.460
includes your brain and your spinal cord,
link |
00:04:22.280
but also all the connections that your brain
link |
00:04:24.500
and spinal cord make with the organs of your body
link |
00:04:27.500
and all the connections that the organs of your body
link |
00:04:30.320
make with your brain and spinal cord.
link |
00:04:32.540
This thing that we call the nervous system
link |
00:04:34.180
is responsible for everything we know,
link |
00:04:36.820
all our behavior, all our emotions,
link |
00:04:39.400
everything we feel about ourselves and the outside world,
link |
00:04:42.080
everything we think and believe, it's really at the center
link |
00:04:45.140
of our entire experience of life and who we are.
link |
00:04:49.400
Fortunately, in humans, unlike in other species,
link |
00:04:53.420
we can change our nervous system
link |
00:04:55.520
by taking some very specific and deliberate actions.
link |
00:04:58.980
And today, we're really going to focus on the actions,
link |
00:05:02.140
the motor commands and the aspects of movement and balance
link |
00:05:07.560
that allow us to change our nervous system.
link |
00:05:09.860
It turns out that movement and balance
link |
00:05:12.260
actually provide windows or portals into our ability
link |
00:05:16.140
to change our nervous system the way we want,
link |
00:05:18.620
even if those changes are not about learning new movements
link |
00:05:22.620
or learning how to balance, and soon you'll understand why.
link |
00:05:26.300
So today, we're going to talk a lot
link |
00:05:28.020
about the basic science of neuroplasticity.
link |
00:05:31.520
I promise to not use excessive nomenclature,
link |
00:05:34.100
there'll be a little bit,
link |
00:05:35.240
but I'll try and make it as clear as possible.
link |
00:05:37.820
And we're also going to talk a lot about protocols and tools
link |
00:05:41.540
that the scientific literature points to and supports
link |
00:05:45.620
for changing our nervous system.
link |
00:05:47.400
Again, not just for sake of learning new motor movements
link |
00:05:50.380
or how to balance better, but for how to feel differently
link |
00:05:54.000
about particular experiences, both past, present and future,
link |
00:05:57.740
as well as how to learn faster.
link |
00:06:00.660
We're not going to discuss hacks, a word I loathe,
link |
00:06:03.640
we're not going to discuss gimmicks,
link |
00:06:05.600
we're going to discuss mechanism and scientific data
link |
00:06:09.160
and the tools that those mechanisms
link |
00:06:10.920
and scientific data point to
link |
00:06:12.980
so that you can tailor your practices around learning
link |
00:06:16.300
to your specific needs and goals.
link |
00:06:19.300
So let's begin by just examining the big picture question,
link |
00:06:23.100
which is does the brain control behavior?
link |
00:06:27.100
And my hope is that everyone is immediately thinking yes.
link |
00:06:30.580
The brain and nervous system, we really should say,
link |
00:06:33.240
because the brain is just one component of the nervous system
link |
00:06:35.580
controls our behavior.
link |
00:06:37.820
How does it do that?
link |
00:06:39.300
Well, there are a couple of different levels
link |
00:06:41.060
that it does that.
link |
00:06:42.400
First of all, if we're talking about movement,
link |
00:06:45.140
behavior generally means movement.
link |
00:06:47.680
If we're talking about movement,
link |
00:06:50.100
we have two categories of neurons that are very important
link |
00:06:53.940
to think about in the context of neuroplasticity.
link |
00:06:56.180
First of all, we have what are called lower motor neurons.
link |
00:07:00.980
These are motor neurons that live in our spinal cord.
link |
00:07:04.780
If for the aficionados out there,
link |
00:07:06.520
for those of you that might be head to medical school
link |
00:07:08.500
or just want to learn more about the anatomy,
link |
00:07:09.940
they live in the ventral horn of the spinal cord,
link |
00:07:11.860
but that doesn't matter.
link |
00:07:13.260
If you don't want to know that,
link |
00:07:14.540
just know that you have these things
link |
00:07:15.700
called lower motor neurons.
link |
00:07:17.700
These are neurons that are in the spinal cord,
link |
00:07:20.180
but they extend a wire that we call an axon
link |
00:07:22.580
out into the peripheral nervous system, into the body.
link |
00:07:26.180
And those neurons connect with muscle.
link |
00:07:29.900
They send electrical potentials out there
link |
00:07:33.060
that allow our muscles to twitch and to contract.
link |
00:07:35.860
As a little point of fact, actually,
link |
00:07:39.500
we don't have muscle memory.
link |
00:07:41.020
There's no such thing as muscle memory.
link |
00:07:42.920
Muscles are dumb.
link |
00:07:44.300
They don't know anything.
link |
00:07:45.900
They don't have a history.
link |
00:07:47.260
They don't have a memory.
link |
00:07:48.320
They don't know anything.
link |
00:07:49.300
It is the neurons that control those muscles
link |
00:07:52.460
and their firing patterns in which all the information
link |
00:07:56.500
for motor patterns are stored.
link |
00:07:58.820
So your ability to walk is not muscle memory.
link |
00:08:01.400
It's neural memory.
link |
00:08:04.340
Now, the lower motor neurons,
link |
00:08:06.500
while smarter than the muscle, so to speak,
link |
00:08:09.180
are not the most brilliant of the motor neurons.
link |
00:08:12.180
They are generally involved in doing what they are told.
link |
00:08:16.340
And they are told what to do from two sources.
link |
00:08:20.140
We have circuits in our brainstem.
link |
00:08:22.580
So this would be kind of around your neck deep in the brain
link |
00:08:25.540
that are called central pattern generators.
link |
00:08:28.180
These are sometimes called CPGs.
link |
00:08:29.940
Central pattern generators are what allow us
link |
00:08:31.980
to generate repetitive patterns of movement.
link |
00:08:34.780
So inhaling and exhaling, inhaling and exhaling,
link |
00:08:37.360
subconsciously is controlled by a central pattern generator.
link |
00:08:41.160
That just means a collection of neurons.
link |
00:08:43.000
If you really want to know,
link |
00:08:43.840
they're called the pre-bot singer neurons
link |
00:08:45.220
discovered by Jack Feldman and colleagues at UCLA.
link |
00:08:47.860
These neurons in the brainstem send information
link |
00:08:51.020
down the phrenic nerve and control the diaphragm.
link |
00:08:54.620
So it goes inhale, exhale, inhale, exhale.
link |
00:08:57.700
And you don't have to think about that.
link |
00:08:58.840
You could think about it,
link |
00:08:59.780
and you could change the durations of inhales and exhales
link |
00:09:02.140
and change that up.
link |
00:09:03.380
But the motor neurons that control that
link |
00:09:06.060
are just responding to what the brain is telling it to do.
link |
00:09:11.180
The other central pattern generators
link |
00:09:13.180
include things like walking.
link |
00:09:15.860
The right limb, left limb, right limb, left limb pattern
link |
00:09:19.840
that we normally associate with walking
link |
00:09:21.820
was learned during childhood.
link |
00:09:23.300
And the central pattern generator, sometimes called CPGs,
link |
00:09:26.620
tell our lower motor neurons fire.
link |
00:09:29.980
Now you fire, now you fire.
link |
00:09:31.380
So they are literally saying right, left, right, left.
link |
00:09:34.600
They are the marching orders from the brainstem
link |
00:09:37.000
to the lower motor neurons.
link |
00:09:38.380
So these lower motor neurons do what they are told.
link |
00:09:40.320
They are obedient little soldiers
link |
00:09:42.140
and they do what they are told.
link |
00:09:43.980
And their job is to make the muscles
link |
00:09:46.220
contract at specific times.
link |
00:09:49.440
Okay, that's all simple.
link |
00:09:52.140
But then there are the upper motor neurons.
link |
00:09:54.360
The upper motor neurons actually reside in our motor cortex
link |
00:09:58.820
way up on top of the brain.
link |
00:10:01.020
And they are involved in sending signals
link |
00:10:04.360
for deliberate action.
link |
00:10:06.500
Okay, so they send signals to the lower motor neurons
link |
00:10:09.340
which are the effectors,
link |
00:10:10.260
the ones that actually control the muscles,
link |
00:10:12.860
but the upper motor neurons are the ones
link |
00:10:14.940
that send very specific signals.
link |
00:10:17.020
For instance, the signals that would allow you
link |
00:10:19.180
to make a cup of coffee in the morning
link |
00:10:20.940
or to deliberately engage in any kind of behavior.
link |
00:10:24.020
Now you can probably make a cup of coffee in the morning
link |
00:10:26.200
without having to think about it too much.
link |
00:10:27.640
It's almost reflexive for you now,
link |
00:10:29.640
which means that a lot of the information
link |
00:10:31.940
about how to perform that particular movement
link |
00:10:34.540
has been passed off to circuitry
link |
00:10:37.220
that's now more or less in the brainstem
link |
00:10:40.020
and below the motor cortex.
link |
00:10:42.260
Now, why am I giving you all this detail?
link |
00:10:44.380
Well, if you want to change motor patterns,
link |
00:10:48.200
you have to know where in the circuitry changes are possible
link |
00:10:51.740
and you ought to know where the changes
link |
00:10:54.260
are most likely to occur.
link |
00:10:56.300
You also need to know how do you signal
link |
00:10:58.980
to the brain and nervous system that a change is necessary.
link |
00:11:03.500
So let's just pause there,
link |
00:11:05.560
return to the initial question that we started with,
link |
00:11:07.800
which is does the brain control behavior?
link |
00:11:10.180
And the answer is yes, and now you know how.
link |
00:11:12.740
It's upper motor neurons, lower motor neurons.
link |
00:11:15.780
You've got these things called central pattern generators
link |
00:11:17.680
and some connection with the muscle.
link |
00:11:18.880
So there you go.
link |
00:11:19.720
So we've just got basically what was the equivalent
link |
00:11:22.660
of the introduction to a college lecture
link |
00:11:25.260
on motor control in the nervous system,
link |
00:11:27.560
but the point today is all about plasticity.
link |
00:11:30.220
How can that be leveraged in order to open up
link |
00:11:33.940
this magical thing that we call plasticity
link |
00:11:36.740
in order to access changes to our emotional experience
link |
00:11:40.500
or to our belief system or to our ability to remember
link |
00:11:45.500
and use specific kinds of information
link |
00:11:47.380
for say math or language, et cetera?
link |
00:11:50.380
Well, what I'm not going to tell you
link |
00:11:52.980
is that you need to go running or you need to go biking
link |
00:11:56.340
or that simply going through motor patterns
link |
00:11:59.260
is going to open up plasticity,
link |
00:12:00.840
because I hate to tell you this,
link |
00:12:02.340
but as beneficial as exercise is,
link |
00:12:04.960
it does not open plasticity unless you do certain things.
link |
00:12:10.180
And I will tell you exactly
link |
00:12:11.440
what those certain things are today.
link |
00:12:13.620
To be clear, I think exercise is wonderful and healthy,
link |
00:12:16.120
can improve cardiovascular function,
link |
00:12:17.660
maintain strength, bone density, all that good stuff,
link |
00:12:20.420
but just working out or doing your exercise
link |
00:12:23.600
of various kinds will not change your nervous system.
link |
00:12:26.680
It will maintain it
link |
00:12:27.860
and it can certainly improve other health metrics,
link |
00:12:30.320
but it is not going to open up the window for plasticity.
link |
00:12:35.480
The question we need to ask
link |
00:12:37.680
is can behavior change the brain?
link |
00:12:40.260
We already agreed that the brain can change behavior,
link |
00:12:43.240
but can behavior change the brain?
link |
00:12:46.220
And the answer is yes,
link |
00:12:47.740
provided that behavior is different enough in specific ways
link |
00:12:52.580
from the behaviors that you already know how to perform.
link |
00:12:55.820
Let me repeat that.
link |
00:12:56.920
Can behavior change the brain?
link |
00:12:58.880
And the answer is yes,
link |
00:13:00.420
provided that behavior is different enough
link |
00:13:03.160
from the sorts of behaviors
link |
00:13:04.480
that you already know how to perform.
link |
00:13:06.940
And I should have added the word well,
link |
00:13:09.280
because you can't obviously perform a behavior
link |
00:13:11.740
that you don't know how to perform
link |
00:13:13.540
because you don't know how to do it yet.
link |
00:13:14.940
But there's a key element to accessing neuroplasticity
link |
00:13:19.440
that frankly, I don't see out there
link |
00:13:22.000
in the general discussion about neuroplasticity.
link |
00:13:25.060
In the general discussion about neuroplasticity
link |
00:13:27.220
and about learning, I hear all these gimmicks
link |
00:13:29.200
about using different ways to remember
link |
00:13:31.100
lots of people's names
link |
00:13:32.220
and arranging things into their first letters
link |
00:13:34.600
and mnemonics and all this kind of stuff,
link |
00:13:36.320
which frankly to me feels really gimmicky.
link |
00:13:38.860
And I think that if you look at super learners,
link |
00:13:42.320
they tend to be people that have a process
link |
00:13:44.960
of say extreme memory,
link |
00:13:47.440
but people who have extreme memory,
link |
00:13:49.800
generally the literature shows us
link |
00:13:51.760
are pretty poor at other things.
link |
00:13:53.760
So I don't think most of us are interested
link |
00:13:56.240
in walking around knowing how to remember everything.
link |
00:13:58.880
In fact, there are some interesting studies
link |
00:14:00.900
looking at humans who over-remember
link |
00:14:04.600
and they suffer tremendously
link |
00:14:06.040
because they remember all sorts of things
link |
00:14:07.520
like the number at the top of the receipt at the bodega
link |
00:14:09.880
that they bought at Coca-Cola 10 years ago.
link |
00:14:12.400
This is useless information for most people.
link |
00:14:16.120
They don't do well in life really.
link |
00:14:18.960
So the goal isn't to remember everything,
link |
00:14:20.720
the goal is to be selective about your brain changes.
link |
00:14:23.600
And when we talk about brain changes,
link |
00:14:25.200
I want to highlight adaptive changes.
link |
00:14:28.300
There's a whole category of things
link |
00:14:29.800
that we're going to discuss
link |
00:14:30.680
when we talk about traumatic brain injury and dementia,
link |
00:14:33.000
a topic for a future episode,
link |
00:14:35.480
about all the things that happen when you have damaged
link |
00:14:38.840
your nervous system or you're missing neurons.
link |
00:14:40.520
But today I really want to talk about something
link |
00:14:43.000
that I think is very near and dear to many of your hearts,
link |
00:14:45.200
which is what are the behaviors that you can engage in
link |
00:14:47.880
to access neuroplasticity
link |
00:14:51.220
so that then you can apply that plasticity
link |
00:14:54.400
to the specific things that you want to learn or unlearn.
link |
00:14:58.520
This is very important because I don't want people
link |
00:15:01.360
to get the impression that we're really talking
link |
00:15:03.920
about learning a bunch of motor movements.
link |
00:15:05.880
You may be an athlete, you might not be an athlete.
link |
00:15:07.840
You might want to learn how to dance, you might not.
link |
00:15:10.260
You might want to learn how to dance
link |
00:15:11.560
and get better at remembering and learning languages,
link |
00:15:14.120
for instance, or at unlearning
link |
00:15:16.640
some difficult emotional experience,
link |
00:15:19.720
meaning you want to remove the emotional load
link |
00:15:21.680
from a particular memory of an experience.
link |
00:15:24.080
What we're talking about today is using behavior
link |
00:15:26.320
as a gate to enter states of mind and body
link |
00:15:30.840
that allow you to access plasticity.
link |
00:15:35.020
So let's talk about the different kinds of plasticity
link |
00:15:37.220
that are available to us,
link |
00:15:39.420
because those will point directly
link |
00:15:41.480
towards the type of protocols that we should engage in
link |
00:15:44.800
to change ourselves for the better,
link |
00:15:46.580
the so-called adaptive plasticity.
link |
00:15:50.320
There is something called representational plasticity.
link |
00:15:52.740
Representational plasticity
link |
00:15:54.200
is just your internal representation of the outside world.
link |
00:15:57.280
So you have a map of auditory space, believe it or not,
link |
00:16:00.220
meaning you have neurons that respond
link |
00:16:02.080
when something over on my right happens,
link |
00:16:04.300
like I'm snapping my fingers over to my right,
link |
00:16:06.360
can't snap as well on my left,
link |
00:16:07.560
which is the whole thing into itself.
link |
00:16:11.000
Yeah, weak over there on the left side.
link |
00:16:12.840
But when I do that,
link |
00:16:14.400
there are different neurons respond to those.
link |
00:16:17.320
We have a map of visual space.
link |
00:16:19.240
Certain neurons are seeing things
link |
00:16:20.520
in certain portions of visual space and not others.
link |
00:16:22.640
We have a map of motor space,
link |
00:16:25.300
meaning when we move our limbs in particular directions,
link |
00:16:27.760
we know where those limbs are,
link |
00:16:30.020
because even if we can't see them,
link |
00:16:32.200
we have what's called proprioceptive feedback.
link |
00:16:34.440
So we have knowledge about where our limbs are.
link |
00:16:36.580
In fact, people that lack certain neurons
link |
00:16:38.960
for proprioceptive feedback,
link |
00:16:41.060
they are very poor at controlling their motor behavior.
link |
00:16:44.120
They get injured a lot.
link |
00:16:45.200
It's actually a terrible situation.
link |
00:16:47.520
So we've got all these representations inside,
link |
00:16:51.920
and we have maps of our motor commands.
link |
00:16:56.160
We know that, for instance,
link |
00:16:57.340
if I want to reach out and grab the pen in front of me,
link |
00:16:59.180
that I need to generate a certain amount of force,
link |
00:17:01.460
so I rarely overshoot.
link |
00:17:03.260
I rarely miss the pen, okay?
link |
00:17:05.760
So our maps of the motor world
link |
00:17:08.480
and our maps of the sensory world are merged.
link |
00:17:12.420
The way to create plasticity
link |
00:17:16.520
is to create mismatches or errors in how we perform things.
link |
00:17:21.280
And this, I think, is an amazing and important feature
link |
00:17:24.220
of neuroplasticity that is highly underappreciated.
link |
00:17:27.000
The way to create plasticity
link |
00:17:30.800
is to send signals to the brain that something is wrong,
link |
00:17:35.340
something is different, and something isn't being achieved.
link |
00:17:38.840
I think this will completely reframe
link |
00:17:40.480
the way that most people think about plasticity.
link |
00:17:42.240
Most of us think about plasticity as,
link |
00:17:44.240
okay, we're going to get into this optimal learning state
link |
00:17:47.080
or flow, and then suddenly we're going to be able
link |
00:17:49.240
to do all the things that we wish that we could do.
link |
00:17:51.460
Well, I hate to break it to you,
link |
00:17:52.400
but flow is an expression of what we already know how to do.
link |
00:17:56.920
It is not a state for learning.
link |
00:17:58.760
And I'm willing to go to bat
link |
00:17:59.840
with any of the flow anistas out there
link |
00:18:02.880
that want to challenge me on that one.
link |
00:18:04.680
Flow is an expression of nervous system capabilities
link |
00:18:07.960
that are already embedded in us.
link |
00:18:10.760
Errors and making errors out of sync
link |
00:18:14.360
with what we would like to do
link |
00:18:16.080
is how our nervous system is cued
link |
00:18:18.360
through very distinct biological mechanisms
link |
00:18:20.960
that something isn't going right,
link |
00:18:23.480
and therefore certain neurochemicals are deployed
link |
00:18:26.680
that'll signal the neural circuits that they have to change.
link |
00:18:30.920
So let's talk about the experiments
link |
00:18:32.480
that support what I just said,
link |
00:18:33.640
because I'm about to tell you that making errors
link |
00:18:36.160
over and over and over again
link |
00:18:38.280
is the route to shaping your nervous system
link |
00:18:40.280
so that it performs better and better and better.
link |
00:18:43.080
And I'm not going to tell you that the last rep of a set
link |
00:18:46.380
where you hit failure in the gym
link |
00:18:47.920
is anything like neuroplasticity.
link |
00:18:50.280
You hear that too, that it's pushing to that point
link |
00:18:53.240
of a cliff where you just can't function anymore.
link |
00:18:55.900
That's the signal, that's not the signal.
link |
00:18:57.900
That's a distinct neuromuscular phenomenon
link |
00:18:59.800
that bears zero resemblance
link |
00:19:01.520
to what it takes to get neuroplasticity.
link |
00:19:03.720
So let's talk about errors and making errors
link |
00:19:06.560
and why and how that triggers the release of chemicals
link |
00:19:09.720
that then allow us to not just learn the thing
link |
00:19:11.920
that we're doing in the motor sense,
link |
00:19:13.840
play the piano, dance, et cetera,
link |
00:19:15.940
but it also creates an environment to milieu within the brain
link |
00:19:19.800
that allows us to then go learn how to couple
link |
00:19:23.800
or uncouple a particular emotion to an experience
link |
00:19:26.200
or better language learning or better mathematical learning.
link |
00:19:29.760
It's a really fundamental aspect of how we're built.
link |
00:19:33.200
And when you look at it,
link |
00:19:34.480
it's actually very straightforward.
link |
00:19:36.000
It's a series of logical steps
link |
00:19:37.920
that once you learn how to open those hatches,
link |
00:19:40.120
it becomes very straightforward to deploy.
link |
00:19:43.020
Last episode, we discussed some of the basic principles
link |
00:19:45.680
of neuroplasticity.
link |
00:19:47.520
If you didn't hear that episode, no problem.
link |
00:19:50.520
I'll just review it quickly,
link |
00:19:52.280
which is that it's a falsehood that everything that we do
link |
00:19:56.440
and experience changes our brain.
link |
00:19:58.360
The brain changes when certain neurochemicals,
link |
00:20:00.600
namely acetylcholine, epinephrine, and dopamine
link |
00:20:04.080
are released in ways and in the specific times
link |
00:20:07.880
that allow for neural circuits to be marked for change
link |
00:20:10.840
and then the change occurs later during sleep.
link |
00:20:13.120
I'll review that later,
link |
00:20:13.980
but basically you need a certain cocktail of chemicals
link |
00:20:16.600
released in the brain in order for a particular behavior
link |
00:20:19.120
to reshape the way that our brain works.
link |
00:20:22.620
So the question really is,
link |
00:20:23.880
what allows those neurochemicals to be released?
link |
00:20:26.580
And last episode, it talked all about focus.
link |
00:20:28.960
If you haven't seen or heard that episode,
link |
00:20:31.500
you might want to check it out
link |
00:20:32.760
about some specific tools and practices
link |
00:20:35.060
that can allow you to build up your capacity for focus
link |
00:20:37.740
and release certain chemicals in that cocktail.
link |
00:20:40.320
But today we're going to talk about the other chemicals
link |
00:20:42.180
in the cocktail, in particular dopamine.
link |
00:20:45.560
And we're really going to center our discussion
link |
00:20:48.560
around this issue of making errors
link |
00:20:51.820
and why making errors is actually the signal
link |
00:20:54.760
that tells the brain, okay, it's time to change,
link |
00:20:57.000
or more generally, it's time to pay attention to things
link |
00:21:01.240
so that you change.
link |
00:21:03.220
And I really want to distinguish this point really clearly,
link |
00:21:07.400
which is that I'm going to talk today a lot about motor
link |
00:21:10.320
and vestibular, meaning balance programs,
link |
00:21:12.880
but not just for learning motor commands and balance,
link |
00:21:16.800
not just for learning new motor skills and balance,
link |
00:21:18.720
but also for setting a stage or a kind of condition
link |
00:21:21.980
in your brain where you can go learn other things as well.
link |
00:21:24.760
So let's talk about some classic experiments
link |
00:21:27.540
that really nail down what's most important
link |
00:21:31.040
in this discussion about plasticity.
link |
00:21:33.540
So I mentioned last episode,
link |
00:21:34.720
and I'll just tell you right now, again,
link |
00:21:36.440
the brain is incredibly plastic from about birth
link |
00:21:40.320
until about age 25.
link |
00:21:42.040
Passive experience will shape the brain
link |
00:21:44.600
just because of the way that the chemicals
link |
00:21:46.880
that are sloshing around in there
link |
00:21:48.380
and the way that the neurons are arranged
link |
00:21:50.000
and all sorts of things.
link |
00:21:51.200
The brain's job is to customize itself
link |
00:21:53.620
in response to its experience.
link |
00:21:55.080
And then somewhere about 25,
link |
00:21:57.280
it's not like the day after your 26th birthday,
link |
00:21:59.640
plasticity closes.
link |
00:22:01.040
There's a kind of tapering off of plasticity,
link |
00:22:03.600
and you need different mechanisms
link |
00:22:06.120
to engage plasticity as an adult.
link |
00:22:09.400
We're mostly going to be talking about adult plasticity today
link |
00:22:11.520
but I got a lot of questions about,
link |
00:22:13.480
well, what about if I'm younger than 25?
link |
00:22:15.920
Well, first of all, that's great.
link |
00:22:18.760
I wish I had a time machine, but I don't.
link |
00:22:22.200
Because as I've said before,
link |
00:22:23.840
the stinger is when you're young,
link |
00:22:25.560
your brain is very plastic,
link |
00:22:26.660
but you have less control over your experience.
link |
00:22:28.620
When you're older,
link |
00:22:29.520
generally you have more control over your experience,
link |
00:22:31.520
but your brain is less plastic.
link |
00:22:33.360
So if you're already asking the question
link |
00:22:35.080
as a 20-year-old or a 15-year-old,
link |
00:22:36.800
what can I do now that's really gonna enhance my brain?
link |
00:22:40.200
I guess the simple question would answer,
link |
00:22:42.080
excuse me, would be an aside
link |
00:22:43.600
which we get the broadest education you can possible.
link |
00:22:46.640
That means math, chemistry, physics, literature, music,
link |
00:22:50.600
learn how to play an instrument.
link |
00:22:51.760
I'm saying that because I wish I had, et cetera.
link |
00:22:54.440
Get a broad training in a number of things
link |
00:22:56.560
and find the thing that really captures your passion
link |
00:22:59.000
and excitement and then put a ton of additional effort there.
link |
00:23:03.220
That's what I recommend, including emotional development.
link |
00:23:06.480
Maybe a topic for a future episode.
link |
00:23:08.560
But if you are an adult or if you are a young person,
link |
00:23:14.640
knowing how to tap into these plasticity mechanisms
link |
00:23:17.760
is very powerful.
link |
00:23:19.800
You need these chemicals deployed in the nervous system
link |
00:23:22.680
in order to mark whatever nerve cells happen to be firing
link |
00:23:25.880
in the time afterward for change.
link |
00:23:27.760
And people are obsessed with asking,
link |
00:23:30.720
what supplements, what drugs, what conditions,
link |
00:23:34.360
what machines will allow for that?
link |
00:23:37.000
But there's a natural set of conditions that allow for that.
link |
00:23:40.500
When we came into this world,
link |
00:23:42.360
we learned to take our different maps of experience,
link |
00:23:46.960
our motor maps, our auditory maps, our visual maps,
link |
00:23:50.460
and to link them, we align those maps.
link |
00:23:53.840
The simplest example is the one I gave before.
link |
00:23:56.000
If I hear something off to my right, like a click,
link |
00:23:58.480
like that, it could come from my finger snapping
link |
00:24:00.160
or it could come from something generated by somebody else
link |
00:24:03.660
or something else to my right, I look to my right.
link |
00:24:07.360
If I hear it on the left, I look to my left.
link |
00:24:09.920
If I hear it right in front of me,
link |
00:24:11.580
I keep looking right in front of me.
link |
00:24:12.880
And if I hear it behind me, I turn around.
link |
00:24:14.920
And that's because our maps of visual space
link |
00:24:18.720
and our maps of auditory space and our maps of motor space
link |
00:24:23.840
are aligned to one another in perfect register.
link |
00:24:27.120
It's an incredible feature of our nervous system.
link |
00:24:29.160
It takes place in a structure called the superior colliculus,
link |
00:24:31.700
although you don't need to know that name.
link |
00:24:33.920
Superior colliculus has layers,
link |
00:24:35.840
literally stacks of neurons like in a sandwich
link |
00:24:39.620
where the zero point right in front of me,
link |
00:24:42.520
or maybe 10 or 15 degrees off to my right
link |
00:24:45.000
or 10 or 15 degrees off to my left
link |
00:24:47.220
are aligned so that the auditory neurons,
link |
00:24:50.560
the ones that care about sounds at 15 degrees to my right,
link |
00:24:54.340
sit directly below the neurons that look at 15 degrees
link |
00:24:58.140
to my right in my visual system.
link |
00:25:00.040
And when I reach over to this direction,
link |
00:25:03.080
there's a signal that's sent down through those layers
link |
00:25:05.960
that says 15 degrees off to the right
link |
00:25:07.720
is the direction to look, it's the direction to listen,
link |
00:25:11.180
and it's the direction to move if I need to move.
link |
00:25:14.200
So there's an alignment, and this is really powerful.
link |
00:25:16.920
And this is what allows us to move through space
link |
00:25:18.920
and function in our lives in a really fluid way.
link |
00:25:22.220
It's set up during development,
link |
00:25:24.240
but there have been some important experiments
link |
00:25:26.880
that have revealed that these maps are plastic,
link |
00:25:30.860
meaning they can shift, they're subject to neuroplasticity,
link |
00:25:34.120
and there are specific rules that allow us to shift them.
link |
00:25:38.280
So here's the key experiment.
link |
00:25:40.800
The key experiment was done by a colleague of mine,
link |
00:25:44.600
who's now retired, but whose work is absolutely fundamental
link |
00:25:47.440
in the field of neuroplasticity, Eric Knudsen.
link |
00:25:50.280
The Knudsen lab and many of the Knudsen lab
link |
00:25:52.860
scientific offspring showed that if one
link |
00:25:57.440
is to wear prism glasses that shift the visual field,
link |
00:26:02.320
that eventually there'll be a shift
link |
00:26:05.040
in the representation of the auditory and motor maps too.
link |
00:26:08.520
Now, what they initially did
link |
00:26:09.800
is they looked at young subjects,
link |
00:26:12.900
and what they did is they moved the visual world
link |
00:26:16.080
by making them wear prism glasses,
link |
00:26:18.440
so that for instance, if my pen is out in front of me
link |
00:26:21.800
at five degrees off center,
link |
00:26:23.620
so just a little bit off center,
link |
00:26:24.880
if you're listening to this,
link |
00:26:25.720
this would be like just a little bit to my right,
link |
00:26:28.280
but in these prism glasses,
link |
00:26:30.440
I actually see that pen way over far on my right,
link |
00:26:34.760
so it's actually here, but I see it over there
link |
00:26:37.880
because I'm wearing prisms on my eyes.
link |
00:26:39.920
What happens is in the first day or so,
link |
00:26:41.800
you ask people or you ask animal subjects or whatever
link |
00:26:45.120
to reach for this object,
link |
00:26:47.360
and they reach to the wrong place
link |
00:26:49.400
because they're seeing it where it isn't.
link |
00:26:52.440
This gets especially complicated
link |
00:26:53.920
when you start including sounds,
link |
00:26:55.360
when you have a thing off to your right making a sound,
link |
00:26:59.600
but the thing is actually right here,
link |
00:27:01.720
so you're hearing the sound at one location
link |
00:27:03.860
and you're seeing the object at another location
link |
00:27:06.140
because you're wearing these prisms,
link |
00:27:07.600
so your image of the world is totally distorted.
link |
00:27:11.400
Or in experiments done by other groups,
link |
00:27:13.840
they wear glasses, subjects wear glasses
link |
00:27:16.360
that completely invert the visual world
link |
00:27:18.920
so that everything is upside down,
link |
00:27:20.620
which is an extreme example of these representational maps
link |
00:27:24.040
being flipped or shifted.
link |
00:27:26.520
But what you find is that in young individuals,
link |
00:27:29.760
within a day or two,
link |
00:27:31.560
they start adjusting their motor behavior
link |
00:27:34.600
in exactly the right way
link |
00:27:36.680
so that they always reach to the correct location.
link |
00:27:39.080
So they hear a sound at one location,
link |
00:27:40.720
they see the object that ought to make that sound
link |
00:27:43.440
at a different location,
link |
00:27:44.560
and they somehow are able to adjust their motor behavior
link |
00:27:48.120
to reach to the correct location.
link |
00:27:50.520
It's incredible, it's absolutely incredible.
link |
00:27:52.720
Or in the case of the people
link |
00:27:53.720
who look at the world upside down,
link |
00:27:55.840
they somehow are able to navigate this upside down world
link |
00:27:59.800
even though we're completely used to
link |
00:28:01.840
our feet being on the floor and not on the ceiling
link |
00:28:03.980
and people not walking at us
link |
00:28:05.120
by hanging off the ceiling like bats, amazing.
link |
00:28:08.640
And what it tells us is that these maps
link |
00:28:11.000
that are aligned to one another
link |
00:28:12.520
can move and shift and rotate and even flip themselves.
link |
00:28:17.520
And it happens best in young individuals.
link |
00:28:21.200
If you do this in older individuals,
link |
00:28:23.760
in most cases it takes a very long time
link |
00:28:26.740
for the maps to shift and in some cases they never shift.
link |
00:28:29.580
So this is a very experimental scenario
link |
00:28:31.680
but it's an important one to understand
link |
00:28:33.460
because it really tamps down the fact
link |
00:28:36.840
that we have the capacity to create dramatic shifts
link |
00:28:41.060
in our representation of the outside world.
link |
00:28:43.220
So how can we get plasticity as adult
link |
00:28:49.480
that mimics the plasticity that we get when we are juveniles?
link |
00:28:53.160
Well, the Knudsen lab and other labs have looked at this
link |
00:28:56.160
and it's really interesting.
link |
00:28:57.960
First of all, we have to ask
link |
00:28:59.040
what is the signal for plasticity?
link |
00:29:00.720
Is it just having prism glasses on?
link |
00:29:02.760
No, because they did that experiment and ruled that out.
link |
00:29:05.760
Is it just the fact that the visual thing is over to my,
link |
00:29:09.740
appears to be far over to my right
link |
00:29:11.360
when in fact it's right in front of me?
link |
00:29:13.040
No, the signal that generates the plasticity
link |
00:29:17.800
is the making of errors.
link |
00:29:21.160
It's the reaches and failures
link |
00:29:23.480
that signal to the nervous system that this is not working
link |
00:29:29.140
and therefore the shifts start to take place.
link |
00:29:32.600
And this is so fundamentally important
link |
00:29:34.640
because I think most people think,
link |
00:29:36.740
oh, well, practice is gonna be,
link |
00:29:38.440
I have to access beginner's mind,
link |
00:29:40.340
which is a great concept actually.
link |
00:29:41.640
It's about approaching things, expecting to make errors,
link |
00:29:43.840
which is great.
link |
00:29:44.680
I think I am a believer in beginner's mind,
link |
00:29:47.360
but people understandably get frustrated.
link |
00:29:50.880
Like they're trying to learn a piece on the piano
link |
00:29:52.640
and they don't know, they can't do it
link |
00:29:54.080
or they're trying to write a piece of code
link |
00:29:55.480
or they're trying to access some sort of motor behavior
link |
00:29:57.800
and they can't do it.
link |
00:29:58.880
And the frustration drives them crazy.
link |
00:30:00.760
And like, I can't do it, I can't do it.
link |
00:30:01.900
When they don't realize that the errors themselves
link |
00:30:05.520
are signaling to the brain and nervous system,
link |
00:30:07.560
something's not working.
link |
00:30:09.000
And of course the brain doesn't understand the words,
link |
00:30:11.480
something isn't working.
link |
00:30:13.280
The brain doesn't even understand frustration
link |
00:30:15.040
as an emotional state.
link |
00:30:16.640
The brain understands the neurochemicals that are released,
link |
00:30:20.720
namely epinephrine and acetylcholine,
link |
00:30:24.680
but also, and we'll get into this, the molecule dopamine,
link |
00:30:27.560
when we start to approximate the correct behavior
link |
00:30:30.200
just a little bit and we start getting a little bit right.
link |
00:30:34.260
So what happens is when we make errors,
link |
00:30:37.000
the nervous system kind of, I don't wanna say freaks out
link |
00:30:39.760
because it's a very mechanistic and controlled situation,
link |
00:30:42.380
but the nervous system starts releasing neurotransmitters
link |
00:30:45.080
and neuromodulators that say,
link |
00:30:46.880
we better change something in the circuitry.
link |
00:30:49.000
And so errors are the basis for neuroplasticity
link |
00:30:52.240
and for learning.
link |
00:30:53.280
And I wish that this was more prominent out there.
link |
00:30:56.400
I guess this is why I'm saying it.
link |
00:30:58.520
And humans do not like this feeling of frustration
link |
00:31:02.000
and making errors.
link |
00:31:03.220
The few that do, do exceedingly well in whatever pursuits
link |
00:31:07.400
they happen to be involved in.
link |
00:31:09.080
The ones that don't generally don't do well.
link |
00:31:12.040
They generally don't learn much.
link |
00:31:13.520
And if you think about it,
link |
00:31:14.360
why would your nervous system ever change?
link |
00:31:16.980
Why would it ever change?
link |
00:31:18.480
Unless there was something to be afraid of,
link |
00:31:20.760
something that made us feel awful will signal
link |
00:31:22.620
that the nervous system needs to change,
link |
00:31:24.360
or there's an error in our performance.
link |
00:31:26.800
So it turns out that the feedback of these errors,
link |
00:31:30.040
the reaching to the wrong location
link |
00:31:32.560
starts to release a number of things.
link |
00:31:34.880
And now you've heard about them many times,
link |
00:31:36.600
but this would be epinephrine, it increases alertness,
link |
00:31:40.220
acetylcholine focus.
link |
00:31:41.760
And this is why frustration that leads us
link |
00:31:44.280
to just kind of quit and walk away from the endeavor
link |
00:31:46.600
is the absolute worst thing.
link |
00:31:48.500
But because if acetylcholine is released,
link |
00:31:51.080
it creates an opportunity to focus on the error margin,
link |
00:31:55.240
the distance between what it is that you're doing
link |
00:31:57.680
and what it is that you would like to do.
link |
00:31:59.800
And then the nervous system starts to make changes
link |
00:32:03.760
almost immediately in order to try
link |
00:32:05.440
and get the behavior right.
link |
00:32:06.800
And when you start getting it even a little bit right,
link |
00:32:09.080
that third molecule comes online or is released,
link |
00:32:11.960
which is dopamine,
link |
00:32:13.240
which allows for the plastic changes to occur very fast.
link |
00:32:16.240
Now, this is what all happens very naturally
link |
00:32:18.200
in young brains, but in old brains,
link |
00:32:21.020
it tends to be pretty slow except for in two conditions.
link |
00:32:25.200
So let me just pause and just say this.
link |
00:32:26.920
If you are uncomfortable making errors
link |
00:32:29.360
and you get frustrated easily,
link |
00:32:32.620
if you leverage that frustration
link |
00:32:37.520
toward drilling deeper into the endeavor,
link |
00:32:40.120
you are setting yourself up
link |
00:32:41.520
for a terrific set of plasticity mechanisms to engage.
link |
00:32:46.040
But if you take that frustration
link |
00:32:47.360
and you walk away from the endeavor,
link |
00:32:49.360
you are essentially setting up plasticity
link |
00:32:52.280
to rewire you according to what happens afterwards,
link |
00:32:55.260
which is generally feeling pretty miserable.
link |
00:32:57.340
So now you can kind of start to appreciate why it is
link |
00:32:59.780
that continuing to drill into a process
link |
00:33:02.020
to the point of frustration,
link |
00:33:03.260
but then staying with that process for a little bit longer,
link |
00:33:06.500
and I'll define exactly what I mean by a little bit,
link |
00:33:08.920
is the most important thing for adult learning,
link |
00:33:14.320
as well as childhood learning,
link |
00:33:15.640
but adult learning in particular.
link |
00:33:17.200
Now, the Newton Lab did two very important
link |
00:33:19.460
sets of experiments.
link |
00:33:21.160
The first one was published in Nature,
link |
00:33:24.640
very important study,
link |
00:33:26.560
which showed that juveniles can make these massive shifts
link |
00:33:31.020
in their map representations,
link |
00:33:32.260
meaning you can shift the visual world using visual prisms
link |
00:33:35.400
a huge amount,
link |
00:33:36.560
and very quickly young individuals
link |
00:33:39.460
can shift their representations of the world
link |
00:33:41.860
so that they learn to reach to the correct location.
link |
00:33:44.120
They get a lot of plasticity all at once,
link |
00:33:47.520
and it happens very fast
link |
00:33:48.600
in the period of just a couple of days.
link |
00:33:51.320
In adults, it tends to be very slow,
link |
00:33:54.160
and most individuals never actually accomplish
link |
00:33:56.760
the full map shift.
link |
00:33:58.840
They don't get the plasticity.
link |
00:34:00.400
And here, we're talking about map shifts,
link |
00:34:01.720
but this could be learning a new language.
link |
00:34:04.640
This could be any number of different things
link |
00:34:06.080
that one were attempting.
link |
00:34:07.320
So what we're saying is what I already said before,
link |
00:34:09.540
which is that we learn very well as youngsters,
link |
00:34:11.720
but not as adults after 25.
link |
00:34:15.560
But then what they did
link |
00:34:17.360
is they started making the increment of change smaller.
link |
00:34:20.680
So instead of shifting the world a huge amount
link |
00:34:24.520
by putting prisms that shifted the visual world
link |
00:34:27.760
all the way over to the right,
link |
00:34:29.360
they did this incrementally.
link |
00:34:30.760
So first, they put on prisms
link |
00:34:32.240
that shifted it just a little bit,
link |
00:34:34.300
just like seven degrees, I believe was the exact number.
link |
00:34:37.040
And then it was 14 degrees, and then it was 28 degrees.
link |
00:34:40.240
And so what they found was that the adult nervous system
link |
00:34:42.960
can tolerate smaller and smaller errors over time,
link |
00:34:47.200
but that you can stack those errors
link |
00:34:49.580
so that you can get a lot of plasticity.
link |
00:34:51.240
Put simply, incremental learning as an adult
link |
00:34:54.480
is absolutely essential.
link |
00:34:55.760
You are not gonna get massive shifts
link |
00:34:57.920
in your representations of the outside world.
link |
00:35:00.120
So how do you make small errors as opposed to big errors?
link |
00:35:03.560
Well, the key is smaller bouts of focused learning
link |
00:35:09.120
for smaller bits of information.
link |
00:35:13.020
It's a mistake to try and learn a lot of information
link |
00:35:17.080
in one learning bout as an adult.
link |
00:35:19.560
What these papers from the Knudsen Lab show
link |
00:35:21.980
and what others have gone on to show
link |
00:35:24.160
is that the adult nervous system is fully capable
link |
00:35:26.560
of engaging in a huge amount of plasticity,
link |
00:35:30.320
but you need to do it in smaller increments
link |
00:35:32.460
per learning epoch or per learning episode.
link |
00:35:35.920
So how would you do this?
link |
00:35:36.840
Well, let's say, for instance, I'm terrible at free throws.
link |
00:35:39.920
So let's say I wanted to learn free throws.
link |
00:35:41.600
I'm 45 years old, so I'm well past the 25 and under mark.
link |
00:35:47.540
I'm gonna make errors, I'm gonna make a lot of errors.
link |
00:35:50.600
If I go into learning free throws,
link |
00:35:53.560
knowing that errors are the gate to plasticity,
link |
00:35:59.400
well, then I feel a little bit better,
link |
00:36:00.840
but I still have to aim for the rim of the basket
link |
00:36:03.400
or the net, basically showing how little
link |
00:36:07.400
I know about basketball.
link |
00:36:08.380
But I think I know the general themes around basketball.
link |
00:36:10.640
It involves a net, a backboard, and a ball, of course.
link |
00:36:13.520
So I go to the free throw line and I'll throw.
link |
00:36:15.820
How long should I go?
link |
00:36:16.720
Well, until I'm hitting the point of frustration,
link |
00:36:19.380
and at that point, continuing probably for anywhere
link |
00:36:24.480
from 10 to 100 more trials should be my limit, right?
link |
00:36:28.860
That should be my limit if I want to improve
link |
00:36:31.500
some specific aspect of the motor behavior.
link |
00:36:34.020
And so the question then is,
link |
00:36:36.020
what should I be paying attention to?
link |
00:36:37.620
What should I be focusing on?
link |
00:36:38.640
Well, obviously trying to get the ball into the basket,
link |
00:36:40.840
but the beauty of motor learning is that the circuits
link |
00:36:43.580
for auditory and visual and motor
link |
00:36:46.140
more or less teach themselves.
link |
00:36:48.060
I don't necessarily have to be paying attention
link |
00:36:50.340
to exactly what the contact of my fingers with the ball
link |
00:36:55.660
or some random feature,
link |
00:36:57.060
like whether or not I'm bending my knees or not.
link |
00:36:59.140
The key is to try a number of different parameters
link |
00:37:02.220
until I start to approximate the behavior
link |
00:37:04.680
that I want to get a little bit better
link |
00:37:06.260
and then trying to get consistent about that.
link |
00:37:08.620
Now, many of you involved in sports learning will say,
link |
00:37:10.780
okay, well, that's obvious, it's just incremental learning.
link |
00:37:13.380
But the key thing is in those errors.
link |
00:37:15.820
By isolating the errors and making a number of errors
link |
00:37:19.880
in a particular aspect of the motor movement,
link |
00:37:22.080
it signals to the brain that it's plastic.
link |
00:37:24.200
And if I leave that episode of going
link |
00:37:27.420
and trying to learn how to shoot free throws,
link |
00:37:30.020
my brain is still plastic.
link |
00:37:31.620
Plasticity is a state of the brain and nervous system.
link |
00:37:34.900
It's not just geared toward the specific thing
link |
00:37:37.120
I'm trying to learn.
link |
00:37:38.340
So there are two aspects to plasticity
link |
00:37:40.180
that I think we really need to highlight.
link |
00:37:41.420
One is that there's plasticity geared toward the thing
link |
00:37:44.700
that you are trying to learn specifically.
link |
00:37:46.780
And then there are states of mind and body
link |
00:37:48.880
that allow us to access plasticity.
link |
00:37:51.700
Now, toward the end of this episode,
link |
00:37:53.120
I'm going to spell out specific protocols
link |
00:37:54.820
in a little more detail.
link |
00:37:55.780
That free throw example might not correlate
link |
00:37:59.300
with what you want to learn.
link |
00:38:00.720
Actually, I don't have a huge desire to learn free throws.
link |
00:38:02.780
I've more or less given up on basketball
link |
00:38:06.020
and free throws in particular.
link |
00:38:07.560
But I think that it's important to understand
link |
00:38:10.300
that motor movements are the most straightforward way
link |
00:38:13.480
to access states of plasticity.
link |
00:38:15.420
And that can be for sake of learning the motor movement
link |
00:38:17.640
or for sake of accessing plasticity more generally.
link |
00:38:21.200
One very important aspect to getting plasticity as an adult
link |
00:38:27.200
is not just smaller increments, meaning shorter bouts.
link |
00:38:30.620
So I gave an example of another 100 free throws or something
link |
00:38:33.480
but going out there and just getting my 10,000 free throws
link |
00:38:37.000
all at once or packing as much as I can into one episode
link |
00:38:41.280
is not going to be as efficient for me
link |
00:38:43.480
as shorter bouts of intense learning as an adult.
link |
00:38:47.720
Because the error signals are not as well defined.
link |
00:38:51.200
To my nervous system,
link |
00:38:52.040
it's not going to know what needs to change.
link |
00:38:54.340
And so this is really the key element
link |
00:38:55.940
of incremental learning,
link |
00:38:57.220
is that you're trying to signal to the nervous system
link |
00:38:59.160
at least one component that needs to change.
link |
00:39:01.100
The nervous system needs to know what the error is.
link |
00:39:04.040
Now, when I shoot free throws, Lord knows,
link |
00:39:06.840
there are a lot of different kinds of errors that happen.
link |
00:39:08.640
Probably the way I'm bending my knees, the arc of the ball,
link |
00:39:11.000
the way I'm organizing my shoulder
link |
00:39:12.400
is probably where my eyes are, lots of things.
link |
00:39:15.120
So which ones to focus on.
link |
00:39:17.160
And that's what I said before,
link |
00:39:18.220
the beauty of the motor system is
link |
00:39:19.680
I don't have to worry about all of that.
link |
00:39:21.840
I just need to get the reps in a number of times
link |
00:39:25.400
and the nervous system will figure out
link |
00:39:27.360
how far off my motor commands are
link |
00:39:30.460
at the level of these maps that I described earlier,
link |
00:39:32.800
how far those deviate from the desired behavior,
link |
00:39:37.960
getting the ball into the basket.
link |
00:39:40.120
And it will start making adjustments.
link |
00:39:42.540
But as I make adjustments,
link |
00:39:45.020
or as my nervous system makes adjustments for me,
link |
00:39:47.280
the key thing is to not start adding a variety of new errors
link |
00:39:51.040
because then it gets confused.
link |
00:39:52.200
And so this is why short learning bouts
link |
00:39:54.260
are absolutely essential.
link |
00:39:55.880
So let's say it's for learning an instrument as an adult,
link |
00:39:59.040
probably anywhere from seven minutes to 30 minutes
link |
00:40:05.440
provided that you're fully attending, you're very focused,
link |
00:40:09.240
is going to be a pretty significant stimulus
link |
00:40:12.760
to inspire plasticity in the nervous system.
link |
00:40:15.320
Now, there is one way to get a lot of plasticity
link |
00:40:19.000
all at once as an adult.
link |
00:40:20.160
There is that kind of holy grail thing
link |
00:40:22.420
of getting massive plasticity
link |
00:40:26.360
as you would when you were a young person, but as an adult.
link |
00:40:31.320
And the Knudsen lab revealed this
link |
00:40:34.760
by setting a very serious contingency on the learning.
link |
00:40:40.120
What they did was they had a situation
link |
00:40:42.400
where subjects had to find food
link |
00:40:46.280
that was displaced in their visual world,
link |
00:40:48.080
again, by putting prisms,
link |
00:40:49.640
and they had to find the food and the food made a noise.
link |
00:40:52.680
There was a noise set kind of the location of the food
link |
00:40:54.680
through an array of speakers.
link |
00:40:56.640
Basically, what they found was that
link |
00:40:58.760
if people have to adjust their visual world
link |
00:41:01.240
in order to get food, the plasticity would eventually occur,
link |
00:41:04.360
but it was very slow as an adult.
link |
00:41:06.800
It was very, very slow.
link |
00:41:08.960
Unless they actually had to hunt that food.
link |
00:41:12.700
They actually, in order to eat at all,
link |
00:41:17.240
they needed plasticity.
link |
00:41:18.960
And then what happened was remarkable.
link |
00:41:21.380
What they observed is that the plasticity as an adult
link |
00:41:24.900
can be as dramatic, as robust as it is in a young person
link |
00:41:29.820
or in a young animal subject,
link |
00:41:32.260
provided that there's a serious incentive
link |
00:41:35.000
for the plasticity to occur.
link |
00:41:37.200
And this is absolutely important to understand,
link |
00:41:39.400
which is that how badly we need or want the plasticity
link |
00:41:44.120
determines how fast that plasticity will arrive,
link |
00:41:47.760
which is incredible because the brain is just neurons
link |
00:41:51.280
and soup of chemicals.
link |
00:41:52.540
So with this, but this means that the importance of something
link |
00:41:55.640
how important something is to us
link |
00:41:57.480
actually gates the rate of plasticity
link |
00:41:59.800
and the magnitude of plasticity.
link |
00:42:01.880
And this is why just passively going through most things,
link |
00:42:06.240
going through the motions, as we say,
link |
00:42:07.880
or just getting our reps in quote unquote
link |
00:42:10.720
is not sufficient to get the nervous system to change.
link |
00:42:14.880
This study, a beautiful study
link |
00:42:18.200
published in the Journal of Neuroscience shows
link |
00:42:20.820
that if we actually have to accomplish something
link |
00:42:24.800
in order to eat or in order to get our ration of income,
link |
00:42:29.800
we will reshape our nervous system very, very quickly.
link |
00:42:33.180
So the nervous system has a capacity to change
link |
00:42:37.680
at a tremendous rate to an enormous degree
link |
00:42:40.780
at any stage of life,
link |
00:42:43.540
provided it's important enough that that happened.
link |
00:42:46.860
And I think some of you might be saying,
link |
00:42:48.380
well, duh, that's obvious.
link |
00:42:49.740
If it's really crucial,
link |
00:42:51.140
then of course it's gonna change faster,
link |
00:42:53.240
but it didn't have to be that way.
link |
00:42:55.020
And for most people who are trying to learn
link |
00:42:57.020
how to learn faster or learn better,
link |
00:43:00.300
they probably, in most cases,
link |
00:43:04.260
they are hitting a limit
link |
00:43:07.100
because the need to change is not crucial enough.
link |
00:43:11.820
And I think there are a number of places
link |
00:43:13.640
where this has an important relevance
link |
00:43:15.260
in the people who are battling addiction, for instance.
link |
00:43:19.620
I will be the first to say that I sympathize with the fact
link |
00:43:22.420
that addictions have a biological component.
link |
00:43:24.880
There's clearly cases where people struggle tremendously
link |
00:43:29.080
to change their behavior and their nervous system,
link |
00:43:31.160
in some cases, is so disrupted
link |
00:43:32.980
by whatever substance they've been abusing
link |
00:43:35.100
or behavior that they've been engaging in
link |
00:43:36.960
that it's that much harder for them to change.
link |
00:43:39.540
But we've also seen incredible examples
link |
00:43:42.080
where when people have to change from an internal standpoint
link |
00:43:46.600
from their own belief and desire to change,
link |
00:43:49.640
that massive change is possible.
link |
00:43:52.120
And so I think that the studies that Knudsen did
link |
00:43:55.140
showing that incremental learning
link |
00:43:56.980
can create a huge degree of plasticity as an adult,
link |
00:44:00.460
as well as when the contingency is very high,
link |
00:44:04.400
meaning we need to eat or we need to make an income
link |
00:44:07.340
or we need to do something that's vitally important for us,
link |
00:44:10.980
that plasticity can happen in these enormous leaps
link |
00:44:15.240
just like they can in adolescence and young adulthood.
link |
00:44:19.120
That points to the fact
link |
00:44:20.160
that it has to be a neurochemical system.
link |
00:44:22.840
There has to be an underlying mechanism, right?
link |
00:44:25.680
This wasn't a case of sticking a wire into the brain
link |
00:44:28.480
or taking a particular drug.
link |
00:44:30.240
All the chemicals that we're about to talk about
link |
00:44:33.120
are released from drug stores, if you will,
link |
00:44:36.400
chemical stores that already reside in all of our brains.
link |
00:44:39.840
And the key is how to tap into those stores.
link |
00:44:43.240
And so we're going to next talk about
link |
00:44:45.120
what are the specific behaviors
link |
00:44:47.320
that liberate particular categories of chemicals
link |
00:44:51.460
that allow us to make the most of incremental learning
link |
00:44:54.520
and that set the stage for plasticity
link |
00:44:57.800
that is similar enough
link |
00:44:59.680
or mimics these high contingency states
link |
00:45:02.640
like the need to get food
link |
00:45:03.900
or really create a sense of internal urgency,
link |
00:45:06.920
chemical urgency, if you will.
link |
00:45:08.980
If you've heard previous episodes of this podcast,
link |
00:45:12.160
you may have heard me talk about ultradian rhythms,
link |
00:45:14.120
which are these 90 minute rhythms
link |
00:45:16.780
that break up our 24 hour day.
link |
00:45:20.240
They help break up our sleep into different cycles of sleep
link |
00:45:23.580
like REM sleep and non-REM sleep.
link |
00:45:25.200
And in waking states, they help us,
link |
00:45:27.920
or I should say they break up our day in ways
link |
00:45:31.000
that allow us to learn best
link |
00:45:32.600
within 90 minute cycles, et cetera.
link |
00:45:34.540
So some of you might be saying,
link |
00:45:35.560
wait, you've been talking about ultradian cycles
link |
00:45:37.360
and a moment ago you were talking about
link |
00:45:39.000
seven minute or 12 minute or 30 minute learning cycles.
link |
00:45:42.080
Today we're really talking about
link |
00:45:43.360
how to tap into plasticity
link |
00:45:46.080
through the completion of a task
link |
00:45:49.340
or working towards something repetitively and making errors.
link |
00:45:53.520
And so just to frame this
link |
00:45:56.000
in the context of the ultradian cycle,
link |
00:45:58.460
you might sit down,
link |
00:45:59.880
decide that you're going to learn a conversational French,
link |
00:46:04.080
which would mean that you probably
link |
00:46:05.160
don't already speak French.
link |
00:46:06.560
So you're going to sit down,
link |
00:46:07.860
you're going to decide,
link |
00:46:09.140
you're going to learn some nouns and some verbs.
link |
00:46:11.520
You might do some practice sets.
link |
00:46:13.040
The ultradian cycle says that
link |
00:46:14.560
for the first five to 10 minutes of doing that,
link |
00:46:17.880
your mind is going to drift
link |
00:46:19.220
and your focus will probably kick in
link |
00:46:21.300
provided that you're restricting your visual world
link |
00:46:24.880
to just the material in front of you,
link |
00:46:26.720
something we talked about last episode,
link |
00:46:28.840
somewhere around the 10 or 15 minute mark.
link |
00:46:31.000
And then at best,
link |
00:46:32.280
you're probably going to get about an hour
link |
00:46:33.940
of deliberate kind of tunnel vision learning in there.
link |
00:46:38.400
Your mind will drift.
link |
00:46:39.880
And then toward the end of that,
link |
00:46:42.160
what is now an hour and 10 or hour and 20 minute cycle,
link |
00:46:45.460
you're going to,
link |
00:46:46.300
your brain will start to flicker in and out.
link |
00:46:48.440
You might start thinking about what you need to eat
link |
00:46:50.240
or the fact that you have to use the bathroom or something.
link |
00:46:52.020
And then by the 90 minutes,
link |
00:46:53.200
it's probably time to just stop the learning bout
link |
00:46:55.040
and go do something else,
link |
00:46:56.720
maybe return for a second learning bout later,
link |
00:46:59.300
but maybe take a nap afterwards
link |
00:47:01.760
or something to enhance the learning,
link |
00:47:03.200
but that it's going to happen within
link |
00:47:05.640
about a 90 minute block,
link |
00:47:06.760
you're going to go through that cycle of learning.
link |
00:47:09.440
But when I refer to the seven or 12 or 30 minutes
link |
00:47:12.760
of making errors,
link |
00:47:13.680
what I mean is when you're really in a mode
link |
00:47:15.920
of repeating errors, not deliberately,
link |
00:47:19.400
you're trying your best to accomplish something
link |
00:47:21.120
and you're failing.
link |
00:47:22.440
You're absolutely failing.
link |
00:47:24.020
You're trying to remember, say, the sign language alphabet.
link |
00:47:28.320
I was trying to teach myself this recently,
link |
00:47:30.080
and then I keep repeating and repeating,
link |
00:47:31.620
and then you get to a certain point
link |
00:47:32.460
where I kept making errors,
link |
00:47:33.840
making errors, making errors.
link |
00:47:35.920
You want to keep making errors for this period of time
link |
00:47:39.780
that I'm saying will last anywhere
link |
00:47:41.320
for about seven to 30 minutes.
link |
00:47:42.640
It is exceedingly frustrating,
link |
00:47:44.920
but that frustration, it liberates the chemical cues
link |
00:47:48.860
that signal that plasticity needs to happen.
link |
00:47:50.960
And they also signal the particular neurons that are active.
link |
00:47:56.120
So in the case of sign language,
link |
00:47:57.160
it might be the ones that control my hand movements
link |
00:47:59.040
as well as me thinking about what the different letters are.
link |
00:48:02.160
It's signaling different components within the networks
link |
00:48:05.800
of between the brain and body.
link |
00:48:07.520
And it's trying to figure out,
link |
00:48:08.940
wait, where are these errors coming from?
link |
00:48:10.860
Where are the errors coming from?
link |
00:48:11.880
Ah, it's those neurons.
link |
00:48:13.540
They're making the mistakes.
link |
00:48:14.840
They're making the mistakes.
link |
00:48:15.800
They're making the mistakes.
link |
00:48:17.180
And it essentially highlights that pathway for change.
link |
00:48:21.580
And it is the case that when we come back a day or two later
link |
00:48:24.280
in a learning bout after a nap or a night or two
link |
00:48:26.760
of deep rest, then what we find is that
link |
00:48:29.400
we can remember certain things and the motor pathways work.
link |
00:48:32.360
And we don't always get it perfectly,
link |
00:48:33.800
but we get a lot of it right whereas we got it wrong before.
link |
00:48:37.040
So that seven to 30 minute intense learning bout
link |
00:48:41.440
is within the ultradian cycle.
link |
00:48:43.020
And I want to be clear about that.
link |
00:48:45.080
And some people can tolerate many of these per day.
link |
00:48:47.440
Most people can only tolerate one or two, maybe three.
link |
00:48:51.720
This is intense work.
link |
00:48:52.920
If, you know, shooting free throws,
link |
00:48:54.720
you could probably do it all day.
link |
00:48:55.880
But what I'm talking about is really trying
link |
00:48:58.100
to accelerate plasticity by having a period
link |
00:49:02.420
of the seven to 30 minutes per learning bout
link |
00:49:05.980
that is specifically about making errors.
link |
00:49:10.400
I want to really underscore that.
link |
00:49:12.500
And it's not about, as I mentioned before,
link |
00:49:15.120
coming up with some little hack or trick
link |
00:49:16.920
or something of that sort.
link |
00:49:19.720
It's really about trying to cue the nervous system
link |
00:49:22.640
that something needs to change
link |
00:49:23.960
because otherwise it simply won't change.
link |
00:49:26.560
Now, there's another aspect to learning.
link |
00:49:30.480
I think it's only fair to mention,
link |
00:49:31.720
which is that we can all learn very easily
link |
00:49:36.460
when there's something very bad happens to us.
link |
00:49:38.440
And I don't wish this on anyone,
link |
00:49:41.020
but it is the case that if something really terrible happens
link |
00:49:43.440
that we will have a lifetime memory for that event.
link |
00:49:47.300
There are processes that allow us to uncouple
link |
00:49:50.160
the emotional load of that event.
link |
00:49:51.600
I talked about some of those a few episodes back,
link |
00:49:55.040
the episode on dreams, trauma, and hallucinations.
link |
00:49:57.640
And we're going to return to trauma release, PTSD,
link |
00:50:00.640
and some of those other themes in a future episode.
link |
00:50:03.000
But the reason why negative experiences
link |
00:50:06.860
can be wired into us so quickly
link |
00:50:08.840
is because our nervous system's main job is to keep us safe.
link |
00:50:12.280
But at a deeper level, it's because negative experiences
link |
00:50:15.920
cue us to the fact that whatever's happening
link |
00:50:17.780
that's really bad is very different
link |
00:50:19.120
than the other things that tend to happen before.
link |
00:50:22.480
So most of our experience doesn't remap us,
link |
00:50:25.180
but those negative experiences
link |
00:50:26.960
deploy high levels of norepinephrine,
link |
00:50:29.240
high levels of acetylcholine, and really make,
link |
00:50:33.360
so that whatever it is that we experience
link |
00:50:36.100
in that bad episode is essentially cued up.
link |
00:50:40.560
And so we're on the lookout for it.
link |
00:50:42.120
And this has a number of negative effects,
link |
00:50:43.800
but in terms of psychological and emotional effects,
link |
00:50:46.520
but it is really a process designed to keep us safe.
link |
00:50:50.360
The other ways in which we can learn more quickly
link |
00:50:54.360
besides just making errors
link |
00:50:56.120
is when something really surprises us.
link |
00:50:58.800
And if we're positively surprised by something,
link |
00:51:01.320
or we are just flooded with this molecule dopamine,
link |
00:51:04.340
then there's a great opportunity for plasticity.
link |
00:51:08.200
Dopamine is a molecule
link |
00:51:09.400
that's almost always associated with pleasure
link |
00:51:11.920
and with the accomplishment of a particular goal,
link |
00:51:14.200
but it's really also a molecule of motivation.
link |
00:51:17.640
It's a molecule that is released inside of us
link |
00:51:19.920
when we think we're on the right path.
link |
00:51:22.320
And it does have a capacity to increase neuroplasticity,
link |
00:51:25.920
motivation, et cetera, it's released in response
link |
00:51:29.320
to a number of natural behaviors,
link |
00:51:31.000
just that help with the progression of ours
link |
00:51:33.600
and other species, things like food, sex,
link |
00:51:39.580
in some sense, social connection,
link |
00:51:41.200
although that's more serotonin,
link |
00:51:42.720
and serotonin doesn't have the same effects on plasticity,
link |
00:51:46.880
quite the same, and we'll talk about a few later.
link |
00:51:49.320
But dopamine is when we think we're on the right path
link |
00:51:52.940
toward an external goal, a little bit is released,
link |
00:51:56.400
and it tends to give us more motivation toward that goal.
link |
00:51:59.040
I think everyone could stand to enhance the rate of learning
link |
00:52:02.500
by doing the following.
link |
00:52:04.480
Learn to attach dopamine in a subjective way
link |
00:52:07.900
to this process of making errors,
link |
00:52:10.120
because that's really combining two modes of plasticity
link |
00:52:13.480
in ways that together can accelerate the plasticity.
link |
00:52:16.840
So earlier I talked about making errors
link |
00:52:18.780
and having a focus bout of learning
link |
00:52:21.540
that includes making a lot of errors
link |
00:52:23.940
inside of that learning bout,
link |
00:52:25.380
that is going to be frustrating,
link |
00:52:26.880
but the frustration itself is the cue,
link |
00:52:30.520
and epinephrine will be very high under those conditions,
link |
00:52:33.960
but if you can just subjectively associate that experience
link |
00:52:38.380
with something good and that you want to continue
link |
00:52:40.800
down that path as opposed to quitting
link |
00:52:42.520
when you hit the point of frustration,
link |
00:52:43.880
well, then you now start to create a synergy
link |
00:52:46.860
between the dopamine that's released
link |
00:52:48.520
when we subjectively think something is good
link |
00:52:50.800
or tell ourselves something is good,
link |
00:52:52.640
and that situation of making failures.
link |
00:52:55.220
In other words, making failing repetitively,
link |
00:52:59.580
provided we're engaged in a very specific set of behaviors
link |
00:53:02.000
when we do it, as well as telling ourselves
link |
00:53:04.320
that those failures are good for learning and good for us,
link |
00:53:07.680
creates an outsized effect on the rate of plasticity.
link |
00:53:11.080
It accelerates plasticity.
link |
00:53:13.380
Now, some of you might be asking, and I get asked a lot,
link |
00:53:16.180
well, how do I get dopamine to be released?
link |
00:53:18.480
Can I just tell myself that something is good
link |
00:53:20.340
when it's bad?
link |
00:53:21.180
Well, actually, yes, believe it or not.
link |
00:53:23.840
The thing about dopamine is it's highly subjective.
link |
00:53:26.180
What's funny to one person
link |
00:53:27.500
is not necessarily funny to the next,
link |
00:53:28.760
so it has to have some sense of authenticity for you,
link |
00:53:32.900
but if you really want to be learning the thing
link |
00:53:35.000
that you're trying to learn,
link |
00:53:36.460
that should be reason enough to tell yourself,
link |
00:53:38.880
well, I'm frustrated,
link |
00:53:40.720
but the frustration is the source of accelerated learning.
link |
00:53:44.560
Dopamine is one of these incredible molecules
link |
00:53:47.560
that both can be released according to things
link |
00:53:50.960
that are hardwired in us to release dopamine.
link |
00:53:53.640
Again, things like food, sex, warmth when we're cold,
link |
00:53:57.280
cool environments when we're too warm.
link |
00:53:59.220
It's that kind of pleasure molecule overall,
link |
00:54:03.040
but it's also highly subjective
link |
00:54:07.240
what releases dopamine in one person versus the next.
link |
00:54:09.860
So everyone releases dopamine
link |
00:54:11.320
in response to those very basic kind of behaviors
link |
00:54:14.120
and activities,
link |
00:54:15.360
but dopamine is also released
link |
00:54:18.340
according to what we subjectively believe is good for us,
link |
00:54:21.400
and that's what's so powerful about it.
link |
00:54:22.960
In fact, a book that I highly recommend
link |
00:54:24.520
if you want to read more about dopamine
link |
00:54:26.220
is a book that, frankly, I wish I had written.
link |
00:54:27.800
It's such a wonderful book.
link |
00:54:28.800
It's called The Molecule of More,
link |
00:54:30.480
and it really talks about dopamine
link |
00:54:32.440
not just as a molecule associated with reward,
link |
00:54:35.360
but a molecule associated with motivation and pursuit
link |
00:54:38.100
and just how subjectively controlled dopamine can be.
link |
00:54:41.560
So make lots of errors.
link |
00:54:44.040
Tell yourself that those errors are important and good
link |
00:54:47.440
for your overall learning goals.
link |
00:54:48.920
So learn to attach dopamine,
link |
00:54:50.600
meaning release dopamine in your brain
link |
00:54:53.860
when you start to make errors.
link |
00:54:55.360
Keep the bouts of learning relatively short
link |
00:54:58.480
if you're an adult.
link |
00:54:59.720
Younger people can probably engage
link |
00:55:02.040
in more bouts of learning,
link |
00:55:03.700
and it's probably one of the reasons
link |
00:55:05.240
why they learn so much faster.
link |
00:55:07.200
They can just pack so much more information
link |
00:55:09.200
into the brains and nervous systems compared to adults.
link |
00:55:11.600
You know, it's a little bit like, I'll use the example
link |
00:55:14.160
of performance-enhancing drugs.
link |
00:55:15.760
You know, some of those drugs
link |
00:55:16.840
probably do enhance performance
link |
00:55:18.560
at the level of increasing red blood cell count, et cetera,
link |
00:55:21.500
but a lot of what those drugs do
link |
00:55:23.440
is they allow athletes to recover faster
link |
00:55:26.180
so they can just train more.
link |
00:55:27.300
They allow them to do more work.
link |
00:55:28.960
And so being a child is a little bit
link |
00:55:30.440
like being in a performance-enhanced brain milieu.
link |
00:55:33.600
Their brains are kind of unnatural, healthy neurochemicals
link |
00:55:37.960
that afford them a lot more learning should they pursue it.
link |
00:55:41.680
So this goes back to my advice for young people early on.
link |
00:55:45.540
If you're young, what should you do?
link |
00:55:47.400
Learn as much as you can
link |
00:55:48.520
about as many things as you possibly can.
link |
00:55:50.340
And I suggest specializing in something.
link |
00:55:52.440
I guess I'm not in a position to give anyone direct advice,
link |
00:55:56.320
but I would say hopefully by about age 30,
link |
00:56:00.760
hopefully younger, you have some sense of what excites you
link |
00:56:03.160
and try and get really good at that thing
link |
00:56:05.200
provided it serves the world for better.
link |
00:56:09.480
But that's all I'll say in terms of parenting advice.
link |
00:56:12.940
It's not my place, but maybe sometime I'll have an episode
link |
00:56:16.880
completely devoted to sort of youth and learning in youth.
link |
00:56:21.160
But once you're attaching dopamine
link |
00:56:23.960
to this process of making errors,
link |
00:56:26.520
then I start getting lots of questions
link |
00:56:28.320
that really are the right questions,
link |
00:56:30.000
which are, you know, how often should I do this?
link |
00:56:33.040
And when should I be doing this?
link |
00:56:34.560
And at what time?
link |
00:56:35.400
Well, I've talked a little bit about this
link |
00:56:36.440
in previous episodes, but as long as we're now
link |
00:56:38.800
kind of into the nitty gritty of tools and application,
link |
00:56:41.640
each of us have some natural times throughout the day
link |
00:56:44.200
when we are going to be much better
link |
00:56:47.640
at tolerating these errors and much more focused
link |
00:56:51.280
on what it is that we're trying to do.
link |
00:56:52.480
Last episode was about focus,
link |
00:56:54.440
but chances are that you can't focus as well at 4 p.m.
link |
00:56:57.920
as you can at 10 a.m.
link |
00:56:59.120
It differs for everybody depending on when you're sleeping
link |
00:57:01.980
and your kind of natural chemistry and rhythms.
link |
00:57:04.320
But find the time or times of day
link |
00:57:07.400
when you naturally have the highest mental acuity.
link |
00:57:10.960
And that's really when you want to engage
link |
00:57:12.720
in these learning bouts.
link |
00:57:14.360
And then get to the point where you're making errors
link |
00:57:16.600
and then keep making errors for seven to 30 minutes.
link |
00:57:19.680
Just keep making those errors and drill through it.
link |
00:57:22.320
And you're almost seeking frustration.
link |
00:57:24.540
And if you can find some pleasure in the frustration,
link |
00:57:26.520
yes, that is a state that exists.
link |
00:57:28.280
You have created the optimal neurochemical milieu
link |
00:57:31.320
for learning that thing.
link |
00:57:33.560
But then here's the beauty of it.
link |
00:57:35.280
You also created the optimal milieu
link |
00:57:37.840
for learning other things afterward.
link |
00:57:40.720
If you leave that bout of,
link |
00:57:42.320
I give the example of free throws,
link |
00:57:43.760
or maybe it's playing tennis,
link |
00:57:44.900
or maybe it's some other skill,
link |
00:57:47.640
and you sit down to read a book,
link |
00:57:49.340
your brain is in a heightened state
link |
00:57:51.860
to learn and retain the information.
link |
00:57:54.460
Because those chemicals don't get released
link |
00:57:56.580
and then shut down.
link |
00:57:57.560
You're creating a whole milieu,
link |
00:57:58.960
an environment of these chemicals.
link |
00:58:01.440
And the tale of how long these chemicals stay
link |
00:58:05.160
sloshing around in your brain has too many factors
link |
00:58:07.240
for me to put a hard number on it.
link |
00:58:08.660
It's going to depend on transporters and enzymes
link |
00:58:10.840
and all sorts of things.
link |
00:58:12.200
But at least for an hour or so, I would say,
link |
00:58:15.320
you're going to be in a state of heightened learning
link |
00:58:18.360
and the ability to learn, not just the motor patterns,
link |
00:58:21.520
but cognitive information, language information.
link |
00:58:24.000
Maybe you go to therapy right after that
link |
00:58:25.980
and you work on something in a very deliberate way
link |
00:58:28.180
that you're trying to work on.
link |
00:58:29.600
Maybe you don't go to therapy.
link |
00:58:31.040
Maybe you do something else that's important to you.
link |
00:58:34.380
Again, there are just a variety of examples I could give.
link |
00:58:37.960
There are a number of things that allow us
link |
00:58:40.400
to powerfully access the states of error
link |
00:58:44.160
that are kind of surprising, but also kind of fun.
link |
00:58:47.860
And these aren't, again, these aren't gimmicks.
link |
00:58:49.780
These tap into these basic mechanisms of plasticity.
link |
00:58:52.960
And the three that I'd like to talk about next
link |
00:58:57.040
are balance, meaning the vestibular system,
link |
00:59:01.240
as well as the two sides of what I call limbic friction
link |
00:59:05.960
or autonomic arousal.
link |
00:59:07.420
And if none of that makes sense,
link |
00:59:08.680
I'm going to put a fine point on each one of those
link |
00:59:11.680
and what it is and why it works
link |
00:59:13.740
for opening up neuroplasticity.
link |
00:59:15.880
Let's talk about limbic friction.
link |
00:59:18.160
Now, limbic friction is not a term
link |
00:59:19.920
you're going to find in the textbooks.
link |
00:59:21.580
So if any of my colleagues are listening,
link |
00:59:23.520
I want to repeat limbic friction.
link |
00:59:25.840
I realize it's not something you're going to find
link |
00:59:27.980
in any of the textbooks.
link |
00:59:29.600
But it is an important principle
link |
00:59:32.300
that captures a lot of information that is in textbooks,
link |
00:59:36.240
both neurobiology and psychology,
link |
00:59:38.300
and it has some really important implications.
link |
00:59:42.800
Limbic friction is my attempt to give a name to something
link |
00:59:46.680
that is more nuanced and mechanistic than stress.
link |
00:59:50.440
Because typically when we hear about stress,
link |
00:59:52.900
we think of heartbeat going too fast, breathing too fast,
link |
00:59:56.800
sweating, and not being in a state that we want.
link |
00:59:59.080
We're too alert and we want to be more calm.
link |
01:00:01.640
And indeed, that's one condition
link |
01:00:03.960
in which we have limbic friction,
link |
01:00:06.700
meaning our limbic system is taking control
link |
01:00:10.420
of a number of different aspects of our autonomic
link |
01:00:12.600
or automatic biology.
link |
01:00:15.160
And we are struggling to control that
link |
01:00:18.740
through what we call top-down mechanisms.
link |
01:00:20.220
We're trying to calm down in order to reduce
link |
01:00:23.040
that level of arousal.
link |
01:00:24.960
We're all familiar with this.
link |
01:00:25.980
It's called the stress response.
link |
01:00:27.580
However, there's another aspect of stress
link |
01:00:30.400
that's just as important, which is when we're tired
link |
01:00:33.800
and we're fatigued and we need to engage,
link |
01:00:36.600
we need to be more alert than we are.
link |
01:00:38.720
And so what I call limbic friction
link |
01:00:40.720
is really designed to describe the fact
link |
01:00:42.680
that when our autonomic nervous system
link |
01:00:44.160
isn't where we want it,
link |
01:00:45.280
meaning we're trying to be more alert
link |
01:00:47.320
or we're trying to be less alert,
link |
01:00:49.180
both of those feel stressful to people.
link |
01:00:51.100
So the other way to put it is that the word stress
link |
01:00:53.720
is not a very good word to describe
link |
01:00:55.440
what most people experience as stressful
link |
01:00:57.160
because it can either be being too tired
link |
01:00:59.920
or being too alert.
link |
01:01:01.220
Now, why am I bringing this up
link |
01:01:02.620
in the discussion about neuroplasticity?
link |
01:01:04.040
This is not a discussion about stress.
link |
01:01:05.560
At some point, we will talk about stress
link |
01:01:07.280
and tools to deal with stress.
link |
01:01:09.640
But the reason I'm bringing this up
link |
01:01:11.680
is that in order to access neuroplasticity,
link |
01:01:15.280
you need these components of focus.
link |
01:01:17.580
You need the component of attaching subjective reward.
link |
01:01:21.560
You need to make errors, all this stuff.
link |
01:01:23.380
And a lot of people find it difficult
link |
01:01:25.780
to just get into the overall state to access those things.
link |
01:01:30.160
So now there's a series of gates
link |
01:01:31.860
that people are having a hard time accessing.
link |
01:01:34.280
They're too tired and they can't focus, for instance.
link |
01:01:36.960
Well, here's the beauty of it.
link |
01:01:39.920
If you are too alert, meaning you're too anxious
link |
01:01:44.440
and you want to calm down in order to learn better,
link |
01:01:47.400
there are things that you can do.
link |
01:01:49.020
The two that I've spoken about previously
link |
01:01:51.600
on various podcasts,
link |
01:01:52.640
and I'll just review them really quickly,
link |
01:01:54.120
are the double inhale-exhale.
link |
01:01:55.700
So inhaling twice through the nose
link |
01:01:57.060
and exhaling once through the mouth.
link |
01:01:58.580
This is not some yogic trick or some hack.
link |
01:02:02.200
This is what's called a physiological psi.
link |
01:02:04.040
It offloads carbon dioxide from the lungs.
link |
01:02:06.300
It has a number of different effects.
link |
01:02:07.680
These were described in textbooks
link |
01:02:08.940
and dating back to the 30s.
link |
01:02:12.000
And a number of laboratories have explored
link |
01:02:14.720
the neural circuitry underlying
link |
01:02:16.160
these so-called physiological psi.
link |
01:02:18.100
That will calm you down faster than anything else
link |
01:02:20.120
that I'm aware of.
link |
01:02:21.920
The other thing is starting to remove your tunnel vision.
link |
01:02:25.040
When you use tunnel vision, you're very focused.
link |
01:02:27.120
That epinephrine is released by dilating your field of gaze,
link |
01:02:30.040
so-called panoramic vision.
link |
01:02:32.100
Great.
link |
01:02:32.940
So now you can start to sort of move up and down
link |
01:02:36.520
this level of autonomic arousal.
link |
01:02:39.160
The key is you want to be in a state of arousal
link |
01:02:42.640
that's ideally matched to the thing
link |
01:02:44.080
that you're trying to perform or learn.
link |
01:02:45.460
So if I'm really anxious
link |
01:02:47.100
and I can't even pick up the basketball
link |
01:02:48.960
or I feel like I'm shaking or my muscles are too tight,
link |
01:02:51.260
I don't have that kind of looseness.
link |
01:02:52.720
Now when I move like that,
link |
01:02:53.840
it almost makes it look like I could throw a free throw,
link |
01:02:56.520
but I miss 95% of the time,
link |
01:03:00.560
unless the basket is very, very low
link |
01:03:02.160
and I place it indirectly.
link |
01:03:03.480
But I guess that's not a free throw, is it?
link |
01:03:06.080
In any case, the point being that you want to be
link |
01:03:09.960
in a state of alertness, but calm.
link |
01:03:12.380
And so you need to have ways to calm yourself down
link |
01:03:14.360
when you're too amped up.
link |
01:03:17.360
But the other side of limbic friction is important too.
link |
01:03:19.520
If you are too tired and you can't focus,
link |
01:03:22.600
well then it's going to be impossible
link |
01:03:23.960
to even get to the starting line, so to speak,
link |
01:03:26.840
for engaging in neuroplasticity
link |
01:03:28.720
through incremental learning, et cetera.
link |
01:03:30.500
So in that case,
link |
01:03:31.900
there are other methods that you can do to wake yourself up.
link |
01:03:34.160
The best thing you should do is get a good night's sleep,
link |
01:03:36.020
but that's not always possible
link |
01:03:37.160
or use a NSDR, non-sleep deep rest protocol.
link |
01:03:39.860
But if you've already done those things
link |
01:03:42.360
or you're simply exhausted for whatever other reason,
link |
01:03:46.160
then there are other things that I often get asked about,
link |
01:03:49.540
like sure, a cup of coffee or super oxygenation breathing,
link |
01:03:52.500
which means inhaling more than exhaling
link |
01:03:54.500
on average in a breathing bout.
link |
01:03:56.480
These are, now we're sort of getting toward the realm
link |
01:03:59.000
of like how you could trick your nervous system
link |
01:04:00.440
into waking up.
link |
01:04:01.320
And if you bring more oxygen in
link |
01:04:02.920
by making your inhales deeper and longer,
link |
01:04:04.520
you will become more alert.
link |
01:04:06.180
You'll start to actually deploy norepinephrine
link |
01:04:08.240
if you breathe very fast.
link |
01:04:09.640
So there are things that you can do to move up or down
link |
01:04:12.520
this so-called autonomic arousal arc.
link |
01:04:15.560
And what you want to ask before you undergo
link |
01:04:17.980
any learning bout is how much limbic friction
link |
01:04:21.160
am I experiencing?
link |
01:04:22.080
Am I too alert and I want to be calmer
link |
01:04:24.800
or am I too calm and too sleepy
link |
01:04:26.920
and I want to be more alert?
link |
01:04:27.960
You're going to need to engage in behaviors
link |
01:04:30.940
that bring you to the starting line in order to learn.
link |
01:04:35.580
There are other things that you can do
link |
01:04:37.000
in order to then learn better and faster
link |
01:04:40.440
besides incremental learning
link |
01:04:41.800
and those center on the vestibular system.
link |
01:04:43.820
And this may come as a surprise to some people,
link |
01:04:45.840
but probably not as a surprise to some of you
link |
01:04:49.360
whose professions or whose recreation
link |
01:04:52.000
involves a lot of motor activity
link |
01:04:54.400
and sort of what we call high dimensional skill activity,
link |
01:04:56.760
not just running or cycling
link |
01:04:58.320
or very linear activities like weightlifting,
link |
01:05:00.280
but things that involve inversions
link |
01:05:01.960
and a lot of lateral movement,
link |
01:05:03.640
actual sports, jumping, diving, rolling,
link |
01:05:06.640
these kinds of things, gymnastics type stuff.
link |
01:05:09.640
Why the vestibular system to access neuroplasticity?
link |
01:05:13.340
Well, we have a hardwired system for balance
link |
01:05:16.820
and here's how it works in as simple terms
link |
01:05:19.400
as I can possibly come up with.
link |
01:05:22.300
As we move through space or even if we're stationary,
link |
01:05:27.720
there are really three main planes of movement.
link |
01:05:29.920
Now I realize some people are just listening to this
link |
01:05:31.560
so I'm going to do this for both the folks
link |
01:05:33.160
that are just listening
link |
01:05:34.080
and for those of you that are watching on video.
link |
01:05:36.200
So there are three main modes of movement
link |
01:05:39.120
and it turns out that your brain doesn't really know
link |
01:05:41.400
where your body is except when
link |
01:05:43.080
through that proprioceptive feedback.
link |
01:05:45.100
The main way it knows is through three planes of movement
link |
01:05:49.160
that we call pitch, which is like nodding.
link |
01:05:51.840
So if I nod like this, that's pitch.
link |
01:05:54.740
Then there's yaw, which is side to side,
link |
01:05:57.400
which is like shaking my head, no.
link |
01:05:59.480
And then there's roll from side to side,
link |
01:06:01.640
like when a puppy looks at you like, that kind of thing.
link |
01:06:05.640
So pitch, yaw, and roll.
link |
01:06:08.480
And the pilots out there will know
link |
01:06:09.800
exactly what I'm talking about.
link |
01:06:12.800
The brain knows the orientation and position
link |
01:06:15.880
of your body relative to gravity,
link |
01:06:18.120
depending on whether or not your brain and your head
link |
01:06:21.680
actually is engaging more in pitch, yaw, or roll,
link |
01:06:25.180
or some combination.
link |
01:06:26.120
Because if I lean down like so,
link |
01:06:28.000
or like so, it's a combination of pitch, yaw, and roll.
link |
01:06:31.160
Now you might say like, what is going on here?
link |
01:06:32.980
Well, we have these little things in our inner ear
link |
01:06:35.920
called the semicircular canals.
link |
01:06:37.580
Just like our eyes have two main functions,
link |
01:06:39.640
one is to see objects in space,
link |
01:06:41.400
and the other is to set our circadian clocks
link |
01:06:43.800
through subconscious mechanisms,
link |
01:06:45.080
our ears have two main roles.
link |
01:06:48.000
One is to hear, right, to perceive sound waves
link |
01:06:51.120
or take in sound waves for perception, so-called hearing.
link |
01:06:54.160
And the other is balance or vestibular function.
link |
01:06:56.600
So sitting in our ears are these semicircular canals,
link |
01:06:59.160
and they're these little tubes where these little stones,
link |
01:07:02.160
they're actually little bits of calcium,
link |
01:07:03.480
roll back and forth like little marbles.
link |
01:07:05.440
When we roll this way, they roll this way.
link |
01:07:07.520
When we pitch, when we go from side to side,
link |
01:07:09.520
there's some that sit flat like this,
link |
01:07:10.860
and they go like marbles inside of a hula hoop.
link |
01:07:14.120
And then we have roll.
link |
01:07:15.120
There's some that are kind of at 45 degrees to those,
link |
01:07:17.240
and it's kind of pitch, yaw, and roll.
link |
01:07:19.400
So yeah, okay, great.
link |
01:07:20.700
That sends signals to the rest of our brain and body
link |
01:07:23.260
that tell us how to compensate
link |
01:07:25.040
for shifts relative to gravity.
link |
01:07:27.680
And I say, okay, wait,
link |
01:07:28.520
I thought we were talking about plasticity,
link |
01:07:29.700
but this is where it gets really, really cool.
link |
01:07:33.160
Errors in vestibular motor sensory experience,
link |
01:07:38.680
meaning when we are off balance and we have to compensate
link |
01:07:42.560
by looking at, thinking about,
link |
01:07:44.800
or responding to the world differently,
link |
01:07:47.440
cause an area of our brain called the cerebellum,
link |
01:07:50.080
it actually means mini brain,
link |
01:07:51.420
and it looks like a little mini brain
link |
01:07:52.980
like tucked below our cortex in the back,
link |
01:07:56.360
cause the cerebellum to signal
link |
01:07:58.360
some of these deeper brain centers
link |
01:08:00.420
that release dopamine, norepinephrine, and acetylcholine.
link |
01:08:03.720
And that's because these circuits in the inner ear,
link |
01:08:08.880
et cetera, and the cerebellum,
link |
01:08:12.100
they were designed to recalibrate our motor movements
link |
01:08:16.880
when our relationship to gravity changes,
link |
01:08:19.560
something fundamental to survival.
link |
01:08:21.000
We can't afford to be falling down all the time
link |
01:08:22.880
or missing things that we grabbed for,
link |
01:08:25.160
or running in the wrong direction
link |
01:08:28.420
when something is pursuing us.
link |
01:08:29.940
These are hardwired circuits
link |
01:08:31.480
that tap right into these chemical pathways.
link |
01:08:34.620
And those chemical pathways are the gates to plasticity.
link |
01:08:38.620
So I really want to spell this out clearly
link |
01:08:40.800
cause I've given a lot of information today.
link |
01:08:43.280
The first thing is how are you arriving
link |
01:08:45.160
to the learning bout?
link |
01:08:47.040
You need to make sure your level
link |
01:08:48.360
of autonomic arousal is correct.
link |
01:08:51.060
The ideal state is going to be clear, calm, and focused,
link |
01:08:54.120
maybe a little bit more on the arousal level,
link |
01:08:56.620
like heightened arousal.
link |
01:08:58.300
So understand limbic friction,
link |
01:09:00.080
understand that you can be too tired,
link |
01:09:01.420
in which case you're going to need
link |
01:09:02.340
to get yourself a little more alert,
link |
01:09:03.920
or you can be too alert
link |
01:09:06.480
and you're going to need to get yourself calmer.
link |
01:09:09.220
That gets you to the starting line.
link |
01:09:11.240
When you're at the starting line,
link |
01:09:12.480
then you're going to go into a learning bout
link |
01:09:13.920
and that's when you want to start making these errors, okay?
link |
01:09:16.840
But what I'm saying is there's a layer in between
link |
01:09:20.160
where if you are interested in using motor patterns
link |
01:09:24.800
as a way to open up plasticity for all kinds of learning,
link |
01:09:27.440
not just motor learning,
link |
01:09:29.920
disrupting your vestibular motor relationship,
link |
01:09:35.560
meaning, and I'll tell you how to do that in a moment,
link |
01:09:37.840
can deploy or release neurochemicals in the brain
link |
01:09:41.280
that place you into a state
link |
01:09:43.480
that makes you much better at learning
link |
01:09:47.000
and making errors much more pleasureful.
link |
01:09:50.400
You're much more willing to do that.
link |
01:09:52.200
Now, some of you are probably saying flow state, flow state.
link |
01:09:54.480
Okay, I have friends that work on flow states
link |
01:09:57.120
and who are involved in flow states
link |
01:09:58.920
and trying to figure out what they are.
link |
01:10:00.300
I have great respect for those people.
link |
01:10:01.800
So I want to tip my hat to them, very important work.
link |
01:10:06.960
But again, flow is an expression
link |
01:10:08.980
of what you already know how to do.
link |
01:10:10.920
It's not how you learn,
link |
01:10:12.960
it's how you express what you've already learned.
link |
01:10:15.600
So I want to be really clear about that.
link |
01:10:17.160
It's been kind of presented as this super state
link |
01:10:19.960
or highly desirable state,
link |
01:10:21.660
but it's that we can all reach for.
link |
01:10:24.340
That's the wrong rung to reach for
link |
01:10:26.200
until you already know how to do the things
link |
01:10:27.800
that I'm describing, in my opinion.
link |
01:10:30.920
So the vestibular system,
link |
01:10:33.040
if you can engage the vestibular system
link |
01:10:35.040
and create some errors within the vestibular motor operations
link |
01:10:38.700
that you're carrying out,
link |
01:10:39.840
you create a neurochemical state
link |
01:10:41.400
that then makes you very, very good
link |
01:10:43.880
at learning very quickly.
link |
01:10:45.460
Regardless of age.
link |
01:10:46.840
So what would this look like?
link |
01:10:48.080
Does this mean just doing inversions?
link |
01:10:49.840
Well, does this mean doing yoga?
link |
01:10:51.960
Maybe.
link |
01:10:52.800
Does this mean taking corners faster on your road bike?
link |
01:10:56.620
Does this mean,
link |
01:10:58.480
let's say you always swim freestyle or breaststroke?
link |
01:11:00.700
Does this mean swimming backstroke or butterfly?
link |
01:11:05.980
It depends.
link |
01:11:07.280
It depends, however,
link |
01:11:08.560
on a very, very easy to understand parameter,
link |
01:11:11.720
which is how regularly you perform
link |
01:11:14.020
a particular motor behavior
link |
01:11:16.640
and how novel a behavior is.
link |
01:11:18.800
So the more novel that a behavior is
link |
01:11:21.340
in terms of your relationship to gravity,
link |
01:11:23.880
the more it will open up the opportunity for plasticity.
link |
01:11:27.520
Have you ever seen somebody
link |
01:11:28.560
who just jumped out of the plane for the first time
link |
01:11:31.520
with a parachute?
link |
01:11:33.820
I don't even want to think about what,
link |
01:11:35.020
if you've just seen somebody who jumped out of a plane
link |
01:11:36.740
for the first time without a parachute,
link |
01:11:38.020
I would just hope the plane was on the ground.
link |
01:11:40.200
But if you've seen somebody after that,
link |
01:11:42.080
they are in this incredible state
link |
01:11:43.740
because their body and brain
link |
01:11:45.480
are flooded with all these neurochemicals
link |
01:11:47.400
because it's very novel to them.
link |
01:11:49.040
However, I've got friends from communities
link |
01:11:51.180
that have done thousands upon thousands,
link |
01:11:53.960
maybe tens of thousands of jumps,
link |
01:11:55.400
and they're always alert and aware,
link |
01:11:57.280
but it becomes pretty regular for them.
link |
01:11:59.320
That's the point.
link |
01:12:00.200
And they're not in this kind of buzzed out,
link |
01:12:02.160
excited state afterwards because it's routine for them.
link |
01:12:05.520
So the key is to bring novelty
link |
01:12:08.000
to the vestibular motor experience.
link |
01:12:11.440
The vestibular motor commands that you're performing.
link |
01:12:15.440
And how do you do that?
link |
01:12:16.900
Well, it's all about your orientation relative to gravity.
link |
01:12:20.640
Now, I wouldn't want anyone to place themselves at risk.
link |
01:12:22.720
So if you can't do handstands,
link |
01:12:24.920
don't try and do them, freestanding and whatever.
link |
01:12:27.800
If you're good at handstands,
link |
01:12:29.000
guess how much plasticity doing a handstands
link |
01:12:31.160
for half an hour is going to create for you?
link |
01:12:33.840
Zero.
link |
01:12:35.280
Zero.
link |
01:12:36.120
Your body is fully comfortable walking on your hands.
link |
01:12:38.600
I see these people walking on your hands,
link |
01:12:40.560
being upside down, being inverted.
link |
01:12:42.120
Your Cirque du Soleil performers,
link |
01:12:43.640
they're very comfortable there.
link |
01:12:44.780
And there's zero learning, zero plasticity
link |
01:12:47.320
because the failures and errors
link |
01:12:48.960
and the relationship to gravity
link |
01:12:51.400
are very typical for that individual.
link |
01:12:54.840
Now, what this means is
link |
01:12:56.560
that if we're going to use motor practices
link |
01:12:58.640
to open up plasticity for learning,
link |
01:13:00.520
not just those practices,
link |
01:13:01.700
but maybe some cognitive skills
link |
01:13:04.160
or other things in the period that follows,
link |
01:13:06.600
we need to create a sense of novelty relative to gravity.
link |
01:13:09.680
And that means being either in a new position
link |
01:13:13.400
or slightly unstable.
link |
01:13:15.320
Believe it or not, I don't want anyone injuring themselves,
link |
01:13:18.280
but the sensation of falling or close to falling
link |
01:13:21.960
signals the cerebellum to signal the deep brain centers
link |
01:13:24.940
that release these neurochemicals
link |
01:13:26.780
that something is very different
link |
01:13:28.120
and we need to correct this error very, very fast.
link |
01:13:31.080
Earlier, I was talking about high contingencies
link |
01:13:33.640
for learning and you definitely don't want to make it
link |
01:13:37.020
to kind of like either survive this or die kind of experience
link |
01:13:40.760
I confess I occasionally look at these parkour videos
link |
01:13:44.300
on YouTube and believe it or not,
link |
01:13:46.360
a lot of those people have died.
link |
01:13:48.280
The ones that do these ridiculous things
link |
01:13:50.720
of hanging off of buildings and things,
link |
01:13:52.220
I am not suggesting you do that, please don't do that.
link |
01:13:54.880
What I'm talking about is finding safe ways
link |
01:13:56.840
to explore the sensory motor vestibular space as we call it,
link |
01:14:01.560
the relationship between those things.
link |
01:14:03.040
So that could be through yoga.
link |
01:14:04.480
If you're terrible at yoga,
link |
01:14:05.600
there's more opportunity for you to learn
link |
01:14:07.040
than somebody who's very skilled at yoga, for instance,
link |
01:14:09.440
or gymnastics or handstands or on your road bike.
link |
01:14:12.280
This is unfortunately what I don't want to name brands,
link |
01:14:15.040
but stationary bikes where they give you
link |
01:14:16.560
the visual experience of moving through space,
link |
01:14:18.600
but you're not actually moving through physical space.
link |
01:14:20.740
There's no vestibular feedback, it's all visual, right?
link |
01:14:25.520
You're stationary on the bike, right?
link |
01:14:27.620
So unless you're hanging off the bike in your living room,
link |
01:14:29.760
like almost to the point you're tipping the bike,
link |
01:14:32.020
you're not getting the actual vestibular motor
link |
01:14:35.160
sensory mismatch.
link |
01:14:36.300
That mismatch is the signal that deploys
link |
01:14:38.680
dopamine epinephrine and these other things.
link |
01:14:40.460
I don't care how excited or how much fun the ride was
link |
01:14:42.880
or how much music you're playing that you love,
link |
01:14:45.160
it's not the same situation as being
link |
01:14:48.720
out of your normal relationship to the gravitational pull.
link |
01:14:55.160
So the first gate is to arrive at learning
link |
01:14:57.320
at the appropriate level of autonomic arousal.
link |
01:15:00.600
Clear and focused is best,
link |
01:15:02.280
but don't obsess over being right there.
link |
01:15:04.460
It's okay to be a little anxious or a little bit tired.
link |
01:15:07.680
Then you want to make errors.
link |
01:15:09.600
We talked about that.
link |
01:15:10.700
And this vestibular motor sensory relationship
link |
01:15:13.600
is absolutely key if you want to get heightened
link |
01:15:17.040
or accelerated plasticity.
link |
01:15:18.840
And we talked about another feature,
link |
01:15:21.380
which is setting a contingency.
link |
01:15:23.400
If there's a reason, an important reason for you
link |
01:15:26.160
to actually learn, even if you're making failures,
link |
01:15:28.860
the learning will be accelerated.
link |
01:15:30.680
So there's really four things
link |
01:15:32.220
that you really need to do for plasticity as an adult.
link |
01:15:36.020
And I would say that these also apply to young people.
link |
01:15:39.680
And there's an interesting
link |
01:15:42.080
kind of a thought experiment there as well,
link |
01:15:44.060
which is if you look at children,
link |
01:15:46.820
they are moving a lot in different dimensions.
link |
01:15:49.840
They are sometimes hanging from trees
link |
01:15:52.400
or I was a kind of a,
link |
01:15:55.100
my sports were always things
link |
01:15:56.280
where I tended to get hurt a lot, fall a lot.
link |
01:15:58.240
So there's a skateboarding for me when I was younger.
link |
01:16:00.120
So a lot of falling and rolling
link |
01:16:01.740
and various things of that sort,
link |
01:16:05.040
but whatever sport the kids are playing,
link |
01:16:06.760
or even if they don't play a sport,
link |
01:16:08.760
they tend to move in a lot of different relationships
link |
01:16:11.880
to gravity, more dimensionality to their movements,
link |
01:16:15.040
I should say, than adults.
link |
01:16:16.480
And one of the questions that's always kind of been
link |
01:16:18.480
in the back of my mind is,
link |
01:16:20.800
as we age, we get less good at engaging in neuroplasticity.
link |
01:16:23.880
Part of that is because as the brain ages,
link |
01:16:26.540
there are certain changes to the way
link |
01:16:28.780
that neurons are structured,
link |
01:16:29.920
their molecular components, et cetera,
link |
01:16:31.920
but it's kind of a self-amplifying,
link |
01:16:35.440
or I should say, a self-degenerating,
link |
01:16:40.560
self-degenerating cycle where as we get older,
link |
01:16:44.520
we tend to get more linear and more regular
link |
01:16:47.800
about the specific kinds of movement.
link |
01:16:49.200
So we get on the treadmill or we take the walk,
link |
01:16:51.400
or we just always go up the same stairs, et cetera,
link |
01:16:53.560
and there's less opportunity typically
link |
01:16:56.500
for engaging these relationships
link |
01:16:58.400
to the gravitational pull
link |
01:17:00.300
through the vestibular motor sensory convergence
link |
01:17:03.160
that we talked about a moment ago.
link |
01:17:05.040
And so you sort of have to wonder
link |
01:17:06.760
whether or not the lack of plasticity
link |
01:17:08.560
or the reduced plasticity in older individuals,
link |
01:17:11.960
which includes me, would reflect the fact
link |
01:17:16.320
that those chemicals aren't being deployed
link |
01:17:18.280
because we're not engaging in certain behaviors,
link |
01:17:21.740
as opposed to we can't engage in the behaviors
link |
01:17:24.200
because the chemicals aren't being deployed.
link |
01:17:26.040
Now, I have a feeling it's both.
link |
01:17:27.280
These have a reciprocal relationship.
link |
01:17:29.240
And I certainly, again, I don't think it would be wise
link |
01:17:32.840
for anyone who doesn't have the muscle stabilizing skills
link |
01:17:36.200
or the bone density, et cetera,
link |
01:17:38.600
to start doing inversions and things of that sort.
link |
01:17:41.160
That's not what I'm talking about here.
link |
01:17:43.160
But it's interesting to think about
link |
01:17:44.560
the sorts of exercise that we engage in.
link |
01:17:46.600
We all know that getting the heart rate elevated
link |
01:17:48.400
three to five times a week is really good for us,
link |
01:17:50.940
for cardiovascular health.
link |
01:17:52.160
I think there's a ton of data to support that now.
link |
01:17:54.780
Some load-bearing exercise is important
link |
01:17:57.260
for increasing bone density
link |
01:17:58.520
and maintaining muscular strength
link |
01:17:59.840
and proprioceptive feedback,
link |
01:18:02.000
because I'm sure many of you know this,
link |
01:18:04.280
but resistance exercise actually trains
link |
01:18:07.440
the nerve to muscle connections
link |
01:18:09.160
as much as it does the muscles themselves,
link |
01:18:11.640
something I talked about at the beginning of the episode.
link |
01:18:14.160
But I think most of us could stand to increase the degree
link |
01:18:19.220
to which we engage this vestibular system in novel ways.
link |
01:18:22.880
And that can be done quite safely
link |
01:18:24.340
through a number of different mechanisms.
link |
01:18:27.200
I'm not a surfer,
link |
01:18:28.160
but people who do that sort of thing
link |
01:18:29.920
are very familiar with orienting their body differently
link |
01:18:32.400
according to the gravitational pull.
link |
01:18:34.600
They're lying down, then they're standing up,
link |
01:18:36.040
then they're turning, they're leaning their head.
link |
01:18:37.840
So again, it's this pitch, yaw, roll thing.
link |
01:18:40.400
And again, if you're very skilled at surfing,
link |
01:18:42.640
you're actually not going to open up plasticity
link |
01:18:44.820
just by surfing.
link |
01:18:45.660
It's in the learning of these new relationships to gravity
link |
01:18:49.700
that the windows for plasticity are enhanced.
link |
01:18:52.800
So I want to make sure that I underscore the fact
link |
01:18:56.480
that this vestibular thing that I've been describing
link |
01:18:59.040
is a way to really accentuate plasticity.
link |
01:19:02.400
It's tapping into an inborn biological mechanism
link |
01:19:06.240
where the cerebellum has outputs
link |
01:19:07.660
to these deep brain nuclei
link |
01:19:09.080
associated with dopamine, acetylcholine, and norepinephrine.
link |
01:19:13.520
You don't want to endanger yourself
link |
01:19:15.020
in the course of pursuing these activities,
link |
01:19:16.940
but it is a powerful mechanism.
link |
01:19:18.820
That's kind of an amplifier on plasticity,
link |
01:19:23.100
as is high contingency.
link |
01:19:24.440
If you really need to learn conversational French
link |
01:19:26.540
to save your relationship,
link |
01:19:28.100
the chances are you're going to learn it.
link |
01:19:29.820
There are limits, of course,
link |
01:19:30.900
to the extent to which one can accentuate
link |
01:19:33.640
or accelerate plasticity.
link |
01:19:35.660
You know, the ceiling on this is not infinite.
link |
01:19:37.860
Although we don't know how high it goes,
link |
01:19:40.020
I think it's reasonable to say
link |
01:19:41.060
that if someone put a gun to my head and said,
link |
01:19:42.740
learn conversational French in the next 120 seconds,
link |
01:19:45.980
that conversational French would be limited
link |
01:19:47.860
probably to just one word,
link |
01:19:49.300
probably the word we or something like that,
link |
01:19:51.620
because I can't stuff in all the knowledge all at once.
link |
01:19:55.380
I mean, I think that's the dream of brain machine interface
link |
01:19:57.780
that one will be able to download a chip
link |
01:19:59.580
into their hippocampus or cortex
link |
01:20:01.740
or some other brain structure
link |
01:20:02.860
that would allow them to download conversational French.
link |
01:20:06.060
And someday we may get to that
link |
01:20:08.940
as that capability may come about.
link |
01:20:11.040
Right now, it does not exist,
link |
01:20:13.100
nor is there a specific pill or chemical
link |
01:20:15.760
that will allow you to download more information
link |
01:20:19.020
more quickly.
link |
01:20:20.480
This is the issue around nootropics
link |
01:20:23.100
I've talked about before.
link |
01:20:24.740
There are things that can increase focus,
link |
01:20:26.740
mainly things that increase acetylcholine
link |
01:20:28.660
and transmission through the nicotine system,
link |
01:20:31.120
things that can increase dopamine, things like L-tyrosine.
link |
01:20:34.060
Again, I'm not recommending these.
link |
01:20:35.540
You need to heed the warnings on those bottles,
link |
01:20:37.340
but they will increase these neurochemicals.
link |
01:20:39.940
And there are, of course,
link |
01:20:41.060
things that will increase epinephrine,
link |
01:20:42.200
things like caffeine or some people,
link |
01:20:44.860
because of prescription, take Adderall.
link |
01:20:47.200
I'm, again, not suggesting people take any of these things.
link |
01:20:49.820
In fact, today I focused almost exclusively
link |
01:20:53.340
on behavioral tools and ways of structuring learning bouts
link |
01:20:57.980
that will allow you to access more plasticity
link |
01:21:00.300
regardless of age.
link |
01:21:01.660
And they center around things that I'm sure
link |
01:21:04.360
if you look around you, you'll see evidence for,
link |
01:21:07.680
oh, incremental learning is powerful,
link |
01:21:09.420
or, oh, the vestibular system
link |
01:21:11.980
can open up opportunities for plasticity.
link |
01:21:13.940
I'm sure that the yogis out there are all saying,
link |
01:21:15.880
wait, this sounds exactly like yoga.
link |
01:21:18.420
We're supposed to push to an edge and do these inversions
link |
01:21:21.860
and do all those sorts of things.
link |
01:21:23.060
Well, I want to be clear.
link |
01:21:23.940
I never said anyone should do inversions.
link |
01:21:25.540
I said that the vestibular system is a valuable portal
link |
01:21:29.180
into some of these neurochemical states
link |
01:21:30.660
that favor plasticity.
link |
01:21:32.120
But not so seldom I hear from the yoga community,
link |
01:21:36.140
and they will say things like,
link |
01:21:37.540
much of what you're saying about how the brain works
link |
01:21:39.660
or neuroplasticity has already been described
link |
01:21:42.500
is embedded in yoga practices.
link |
01:21:44.300
And I just want to be very clear.
link |
01:21:45.420
I have tremendous respect for the yoga community
link |
01:21:48.600
and the practices.
link |
01:21:49.700
I've done yoga from time to time.
link |
01:21:51.060
I find it challenging and valuable.
link |
01:21:52.900
I'm not a regular practitioner.
link |
01:21:54.900
But the problem with yoga
link |
01:21:57.980
is exactly the same problem with science,
link |
01:22:00.840
which is that yoga has a lot of practices
link |
01:22:05.740
for which there are very specific names,
link |
01:22:08.300
but no description or lending of understanding
link |
01:22:11.680
about mechanism.
link |
01:22:13.140
And science has a lot of mechanisms
link |
01:22:16.260
and a lot of publications and papers
link |
01:22:17.780
for which there's very little, if not no description
link |
01:22:20.460
of tools and practices.
link |
01:22:22.260
So my goal in not just today,
link |
01:22:26.220
but in many ways throughout the course of the podcast
link |
01:22:28.640
is to bridge the gaps between these various disciplines
link |
01:22:32.080
in ways that are grounded mainly
link |
01:22:34.340
to the fields of neuroscience and some related fields.
link |
01:22:37.780
So yes, it's true that I look at things
link |
01:22:40.320
mainly through the lens of science,
link |
01:22:41.900
but that's not to say
link |
01:22:43.260
that it exhaustively explains everything about anything,
link |
01:22:47.140
nor is it to say that it's the only lens
link |
01:22:49.180
through which one could look at
link |
01:22:50.460
something like neuroplasticity.
link |
01:22:52.180
So I just want to acknowledge that I have great respect
link |
01:22:54.680
for all these different practices and communities.
link |
01:22:56.780
And I think that indeed,
link |
01:22:58.880
there are many cases in which
link |
01:23:00.700
different communities and practices
link |
01:23:02.380
have been aimed at targeting the same goals or outcomes.
link |
01:23:07.340
Science and neuroscience
link |
01:23:09.040
through an understanding of mechanism
link |
01:23:11.240
can allow all of us
link |
01:23:13.160
to gain a kind of common understanding
link |
01:23:15.420
about what those practices are
link |
01:23:16.820
and how to access things like neuroplasticity,
link |
01:23:19.020
sleep, et cetera.
link |
01:23:20.860
And I do believe, as I've said previously on this podcast,
link |
01:23:24.500
that understanding mechanism
link |
01:23:25.980
affords us a certain flexibility,
link |
01:23:28.100
and I don't mean physical flexibility.
link |
01:23:30.060
I mean a flexibility
link |
01:23:31.460
when we can't engage in a particular behavior,
link |
01:23:34.340
maybe we're injured
link |
01:23:35.260
or maybe we're not in the right situation
link |
01:23:37.020
to do a particular practice,
link |
01:23:38.720
but by thinking about mechanism,
link |
01:23:40.620
we can adapt our circumstances.
link |
01:23:43.020
I've talked about this with sleep.
link |
01:23:44.940
If you're rigidly attached to one protocol
link |
01:23:47.300
of always looking at sunlight
link |
01:23:48.500
at one particular time in the morning and in the evening,
link |
01:23:50.980
that is not as valuable as understanding the mechanisms
link |
01:23:53.960
of why you might look at sunlight
link |
01:23:55.940
at one particular time versus another,
link |
01:23:57.800
because that affords you a flexibility,
link |
01:23:59.620
allows you to adapt,
link |
01:24:00.640
and life is very dynamic,
link |
01:24:02.400
and we don't have control
link |
01:24:03.780
over all the external conditions all the time.
link |
01:24:06.580
And so understanding mechanism
link |
01:24:08.360
through the lens of neuroscience,
link |
01:24:09.500
I do believe can be very powerful
link |
01:24:11.500
because of course there are multiple ways to access dopamine.
link |
01:24:14.660
There are multiple ways to adjust limbic friction.
link |
01:24:17.080
It's not just through respiration.
link |
01:24:19.240
Of course, there are many ways to do that.
link |
01:24:21.880
And so my overall goal here in this episode
link |
01:24:25.060
and with this podcast
link |
01:24:26.460
is to give you some understanding of the mechanisms
link |
01:24:29.700
and the insights into the underlying biology
link |
01:24:32.100
that allow you to tailor
link |
01:24:33.960
what these kind of foundational mechanisms are
link |
01:24:38.060
to suit your particular learning needs.
link |
01:24:40.760
So I really thank you for your time and attention today.
link |
01:24:44.000
I've covered a lot of material.
link |
01:24:45.500
I very much encourage questions in the comment section
link |
01:24:49.000
if you're looking at this on YouTube,
link |
01:24:51.020
and if you're not and you're listening to it
link |
01:24:52.700
on Apple or Spotify,
link |
01:24:54.100
please feel free to visit us over on the YouTube channel
link |
01:24:57.780
and put your questions in the comment section.
link |
01:24:59.700
I do read them.
link |
01:25:00.600
This entire month is all about neuroplasticity.
link |
01:25:02.780
There's a lot to cover,
link |
01:25:04.180
but I'm very excited to delve deeper into this topic
link |
01:25:06.600
as it relates to your particular interests.
link |
01:25:09.100
Many of you have graciously asked
link |
01:25:10.540
how you can help support the podcast.
link |
01:25:12.700
The best way you can do that
link |
01:25:13.860
is to subscribe to the YouTube channel
link |
01:25:15.980
if you haven't done that already,
link |
01:25:17.700
as well as to place questions in the comment section below
link |
01:25:20.660
or comments if you'd like to give us feedback.
link |
01:25:23.160
Also to subscribe on Apple and or Spotify,
link |
01:25:27.020
and Apple allows you to leave a five-star review
link |
01:25:29.740
if you believe we deserve a five-star review,
link |
01:25:32.120
as well as leave comments about the podcast.
link |
01:25:35.020
In addition, if you can suggest the podcast
link |
01:25:37.940
to your friends, to your family members,
link |
01:25:39.880
or anyone that you think might be able to use
link |
01:25:42.300
and appreciate the information,
link |
01:25:43.660
that's a terrific way to support us.
link |
01:25:45.500
And of course, check out our sponsors
link |
01:25:47.340
that we mentioned at the beginning.
link |
01:25:48.580
That's a terrific way to support us as well.
link |
01:25:51.160
Several times throughout today's episode,
link |
01:25:53.060
as well as on previous episodes of the podcast,
link |
01:25:55.780
I've talked about various supplements
link |
01:25:57.700
that can be useful for enhancing sleep,
link |
01:26:00.620
enhancing neuroplasticity, et cetera.
link |
01:26:03.140
And again, I want to emphasize that I always think
link |
01:26:05.780
that behavioral practices are the place to start.
link |
01:26:08.740
I don't think supplements should ever be
link |
01:26:10.380
the first line of entry for people looking
link |
01:26:12.580
to enhance these aspects of their nervous system in life.
link |
01:26:15.340
But for those of you that are interested in supplements
link |
01:26:17.700
and the supplements that I take,
link |
01:26:19.260
I'm pleased to announce that we partnered with Thorne,
link |
01:26:21.600
T-H-O-R-N-E, and Thorne makes supplements
link |
01:26:25.700
that are, in my opinion, of the very highest stringency
link |
01:26:28.720
in terms of what's listed on the bottle
link |
01:26:31.260
is actually what you'll find in the bottle.
link |
01:26:32.940
This is a serious issue for the supplement industry,
link |
01:26:35.380
as well as just the overall quality
link |
01:26:37.420
of the materials they put into their supplements.
link |
01:26:39.960
If you'd like to take a look at the supplements
link |
01:26:41.580
that I take, as well as explore any of them for yourself,
link |
01:26:45.380
you can go to Thorne.com slash U slash Huberman.
link |
01:26:50.540
And if you look there, you'll see a number
link |
01:26:52.180
of the different supplements that I take.
link |
01:26:53.920
And if you decide to purchase any of them,
link |
01:26:55.940
you'll get 20% off your order.
link |
01:26:57.580
So that's Thorne, T-H-O-R-N-E slash U slash Huberman
link |
01:27:02.540
to see the supplements that I take
link |
01:27:03.940
and to explore if any of them are right for you.
link |
01:27:07.540
In the next episode of this podcast,
link |
01:27:09.180
we're going to continue to explore neuroplasticity.
link |
01:27:12.340
This, as you may recall, is the way that we go about things
link |
01:27:15.040
here at the Huberman Lab Podcast,
link |
01:27:16.420
which is to really drill deeply into a topic
link |
01:27:19.300
for three or four or even five episodes
link |
01:27:21.940
so that by the end of those episodes,
link |
01:27:24.120
all of you have a very firm understanding
link |
01:27:26.220
of how to apply the principles of neurobiology
link |
01:27:28.940
to the specific practices and endeavors
link |
01:27:31.540
that are most important to you.
link |
01:27:33.300
So I very much thank you for your time and attention.
link |
01:27:36.100
I know it's a lot of information
link |
01:27:38.020
and it takes a bit of focus and attention
link |
01:27:40.460
and certainly will trigger plasticity
link |
01:27:43.140
to learn all this information.
link |
01:27:45.140
I want to encourage you and just remind you
link |
01:27:47.480
that you don't have to grasp it all at once,
link |
01:27:49.940
that it is here archived.
link |
01:27:51.580
And then if you want to return to the information,
link |
01:27:53.440
it will still be here.
link |
01:27:54.900
And that I most of all really appreciate
link |
01:27:58.040
your interest in science.
link |
01:27:59.340
Thank you so much.
link |
01:28:00.180
Thank you.
link |
01:28:01.700
Thank you.
link |
01:28:02.540
Thank you.
link |
01:28:03.380
Thank you.