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How Your Nervous System Works & Changes | Huberman Lab Podcast #1



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Welcome to the Huberman Lab Podcast,
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where we discuss science and science-based tools
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for everyday life.
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I'm Andrew Huberman,
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and I'm a professor of neurobiology and ophthalmology
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at Stanford School of Medicine.
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For today's podcast,
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we're going to talk about the parts list
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of the nervous system.
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Now that might sound boring,
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but these are the bits and pieces that together
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make up everything about your experience of life,
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from what you think about to what you feel,
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what you imagine, and what you accomplish
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from the day you're born until the day you die.
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That parts list is really incredible
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because it has a history associated with it
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that really provides a window into all sorts of things
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like engineering, warfare, religion, and philosophy.
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So I'm gonna share with you the parts list
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that makes up who you are
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through the lens of some of those other aspects of life
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and other aspects of the history of the discovery
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of the nervous system.
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By the end of this podcast,
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I promise you're gonna understand a lot more
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about how you work and how to apply that knowledge.
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There's gonna be a little bit of story.
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There's gonna be a lot of discussion about the people
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who made these particular discoveries.
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There'll be a little bit of technical language.
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There's no way to avoid that.
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But at the end, you're gonna have in hand
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what will be the equivalent of an entire semester
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of learning about the nervous system and how you work.
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So a few important points before we get started.
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I am not a medical doctor.
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That means I don't prescribe anything.
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I'm a professor.
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So sometimes I'll profess things.
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In fact, I profess a lot of things.
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We are going to talk about some basic functioning
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of the nervous system, parts, et cetera.
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But we're also gonna talk about how to apply that knowledge.
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That said, your healthcare,
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your wellbeing is your responsibility.
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So anytime we talk about tools,
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please filter it through that responsibility.
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Talk to a healthcare professional
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if you're gonna explore any new tools or practices.
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And be smart in your pursuit of these new tools.
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I also wanna emphasize that this podcast
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and the other things I do on social media
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are my personal goal of bringing zero cost
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to consumer information to the general public.
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It is separate from my role at Stanford University.
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In that spirit, I really wanna thank the sponsors
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of today's podcast.
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The first one is Athletic Greens,
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which is an all-in-one drink.
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It's a greens drink that has vitamins, minerals,
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probiotics, prebiotics.
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I've been using Athletic Greens since 2012.
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So I'm really delighted that they're sponsoring the podcast.
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The reason I like it is because
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I like vitamins and minerals.
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I think they're important to my health
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and it can be kind of overwhelming to know
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what to take in that landscape.
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So by taking one thing that also happens to taste really
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good, I get all the vitamins, minerals, et cetera
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that I need.
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There's also a lot of data out there now
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about the importance of the gut microbiome
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for immune health and for the gut brain access,
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all these things.
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And the probiotics and prebiotics are important to me
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for that reason.
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If you wanna try Athletic Greens,
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you can go to athleticgreens.com slash Huberman
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and put in the code word Huberman at checkout.
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If you do that, they'll send you a year supply
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of vitamin D3 and K2.
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There's a lot in the news lately
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about the importance of vitamin D3.
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We can all get vitamin D3 from sunlight,
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but many of us aren't getting enough sunlight.
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Vitamin D3 has been shown to be relevant
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to the immune system and the hormone systems, et cetera.
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So once again, that's athleticgreens.com slash Huberman,
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enter Huberman at checkout and you get the year supply
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of D3 and K2 along with your Athletic Greens.
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This podcast is also brought to us by Inside Tracker,
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which is a health monitoring company.
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It uses blood tests and saliva tests
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to look at things like DNA and metabolic markers
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and monitors your hormones,
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a huge number of different parameters of health
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that really can only be measured accurately
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through blood and saliva tests.
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I use Inside Tracker because I'm a big believer in data.
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There's a lot of aspects to our biology
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that can only be accurately measured
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by way of blood test and saliva test.
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The thing that's really nice about Inside Tracker
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is that rather than just giving you a bunch of numbers back
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of the levels of these things in your body,
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it gives you through a really simple platform information
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about what to do with all those levels of hormones
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and metabolic markers, et cetera.
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It also has a feature which is particularly interesting,
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which it measures your inner age,
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which is more a measure of your biological age
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as opposed to your chronological age.
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And all that information is organized
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so that you can make changes in your nutritional regimes
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or your exercise regimes
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and watch how those markers change over time.
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So if you wanna try Inside Tracker,
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you can go to insidetracker.com slash Huberman
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and they'll give you 25% off at checkout.
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So let's talk about the nervous system.
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The reason I say your nervous system and not your brain
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is because your brain is actually just one piece
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of this larger, more important thing, frankly,
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that we call the nervous system.
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The nervous system includes your brain and your spinal cord,
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but also all the connections between your brain
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and your spinal cord and the organs of your body.
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It also includes, very importantly,
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all the connections between your organs
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back to your spinal cord and brain.
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So the way to think about how you function at every level
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from the moment you're born until the day you die,
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everything you think and remember and feel and imagine
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is that your nervous system is this continuous loop
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of communication between the brain, spinal cord and body
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and body, spinal cord and brain.
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In fact, we really can't even separate them.
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It's one continuous loop.
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You may have heard of something called a Mobius strip.
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A Mobius strip is almost like one of these impossible figures
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that no matter which angle you look at it from,
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you can't tell where it starts and where it ends.
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And that's really how your nervous system is built.
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That's the structure that allows you to, for instance,
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deploy immune cells, to release cells
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that will go kill infection
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when you're in the presence of infection.
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Most people just think about that
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as a function of the immune system,
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but actually it's your nervous system
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that tells organs like your spleen to release killer cells
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that go and hunt down those bacterial and viral invaders
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and gobble them up.
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If you have a stomach ache, for instance,
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sure, you feel that in your stomach,
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but it's really your nervous system
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that's causing the stomach ache.
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The ache aspect of it is a nervous system feature.
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So when we wanna talk about experience
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or we wanna talk about how to change the self in any way,
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we really need to think about the nervous system first.
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It is fair to say that the nervous system
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governs all other biological systems of the body
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and it's also influenced by those other biological systems.
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So if we're talking about the nervous system,
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we need to get a little specific about what we mean.
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It's not just this big loop of wires.
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In fact, there's a interesting story about that
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because at the turn of the sort of 1800s to 1900s,
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it actually was believed that our nervous system
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was just one giant cell.
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But two guys, the names aren't super important,
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but in fairness to their important discovery,
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Ramon y Cajal, a Spaniard, Camillo Golgi, an Italian guy,
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figured out how to label or stain the nervous system
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in a way that revealed, oh my goodness,
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we're actually made up of trillions of these little cells,
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nerve cells that are called neurons.
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And that's what a neuron is, it's just a nerve cell.
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They also saw that those nerve cells
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weren't touching one another.
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They're actually separated by little gaps
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and those little gaps you may have heard of before,
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they're called synapses.
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Those synapses are where the chemicals from one neuron
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are kind of spit out or vomited into
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and then the next nerve cell detects those chemicals
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and then passes electricity down its length
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to the next nerve cell and so forth.
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So really the way to think about your body
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and your thoughts and your mind
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is that you are a flow of electricity, right?
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There's nothing mystical about this.
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You're a flow of electricity
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between these different nerve cells
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and depending on which nerve cells are active,
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you might be lifting your arm or lowering your arm.
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You might be seeing something and perceiving that it's red
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or you might be seeing something and perceiving that
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it's green all depending on which nerve cells
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are electrically active at a given moment.
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The example of perceiving red or perceiving green
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is a particularly good example
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because so often our experience of the world
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makes it seem as if these things that are happening
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outside us are actually happening inside us.
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But the language of the nervous system is just electricity.
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It's just like a Morse code of some sort
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or the syllables and words and consonants
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and vowels of language.
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It just depends on how they're assembled, what order.
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And so that brings us to the issue
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of how the nervous system works.
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The way to think about how the nervous system works
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is that our experiences, our memories, everything
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is sort of like the keys on a piano
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being played in a particular order, right?
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If I play the keys on a piano in a particular order
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and with a particular intensity, that's a given song.
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We can make that analogous to a given experience.
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It's not really that the key A-sharp or E-flat is the song.
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It's just one component of the song.
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So when you hear that, for instance,
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there's a brain area called the hippocampus,
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which there is, that's involved in memory.
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Well, it's involved in memory,
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but it's not that memories are stored there as sentences.
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They're stored there as patterns of electricity and neurons
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that when repeated give you the sense
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that you are experiencing the thing again.
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In fact, deja vu, the sense that what you're experiencing
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is so familiar and like something
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that you've experienced previously
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is merely that the neurons that were active
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in one circumstance are now becoming active
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in the same circumstance again.
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And so it's really just like hearing the same song
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maybe not played on a piano,
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but next time on a classical guitar,
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there's something similar about that song,
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even though it's being played on two different instruments.
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So I think it's important that people understand
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the parts of their nervous system
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and that it includes so much more than just the brain
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and that there are these things, neurons and synapses,
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but really that it's the electrical activity of these neurons
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that dictates our experience.
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So if the early 1900s
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were when these neurons were discovered,
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certainly a lot has happened since then.
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And in that time between the early 1900s and now,
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there's some important events that actually happened
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in history that give us insight
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or gave us insight into how the nervous system works.
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One of the more surprising ones was actually warfare.
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So as most everybody knows in warfare,
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people get shot and people often die,
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but many people get shot and they don't die.
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And in World War I,
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there were some changes in artillery, in bullets,
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that made for a situation where bullets would enter
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the body and brain at very discreet locations
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and would go out the other side of the body or brain
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and also make a very small hole at that exit location.
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And in doing so produced a lot of naturally occurring
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lesions of the nervous system.
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Now you say, okay, well, how does that relate
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to neuroscience?
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Well, unlike previous years where a lot of the artillery
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would create these big sort of holes
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as the bullets would blow out of the brain or body,
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I know this is rather gruesome,
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when the holes were very discreet,
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they entered at one point and left at another point,
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they would take out or destroy very discreet bits
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of neural tissue of the nervous system.
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So people were coming back from war
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with holes in their brain and in other parts
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of their nervous system that were limited
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to very specific locations.
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In addition to that, there was some advancement
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in the cleaning of wounds that happened,
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so many more people were surviving.
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What this meant was that neurologists now had a collection
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of patients that would come back and they'd have holes
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in very specific locations of their brain
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and they'd say things like, well, I can recognize faces,
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but I can't recognize who those faces belong to.
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I know it's a face, but I don't know who it belongs to.
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And after that person eventually died,
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the neurologist would figure out,
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ah, I've had 10 patients that all told me
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that they couldn't recognize faces
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and they all had these bullet holes
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that went through a particular region of the brain
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and that's how we know a lot
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about how particular brain regions like the hippocampus work.
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In fact, some of the more amazing examples of this
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where people would come back and they, for instance,
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would speak in complete gibberish,
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whereas previously they could speak normally.
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And even though they were speaking in complete gibberish,
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they could understand language perfectly.
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That's how we know that speech and language
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are actually controlled by separate portions
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of the nervous system.
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And there are many examples like that,
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people that couldn't recognize the faces of famous people.
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Or, and that actually brings us to an interesting example
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in modern times.
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Many, many years later in the early 2000s,
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there was actually a paper that was published
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in the journal Nature, excellent journal,
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showing that in a human being,
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a perfectly healthy human being,
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there was a neuron that would become active,
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electrically active only when the person viewed
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the picture of Jennifer Aniston, the actress.
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So literally a neuron that represented Jennifer Aniston,
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so-called Jennifer Aniston cells.
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Neuroscientists know about these Jennifer Aniston cells.
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If you can recognize Jennifer Aniston's face,
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you have Jennifer Aniston neurons
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and presumably also have neurons that can recognize
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the faces of other famous and non-famous people.
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So that indicates that our brain is really a map
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of our experience.
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We come into the world and our brain has a kind of bias
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towards learning particular kinds of things.
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It's ready to receive information
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and learn that information,
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but the brain is really a map of experience.
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So let's talk about what experience really is.
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What does it mean for your brain to work?
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Well, I think it's fair to say
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that the nervous system really does five things, maybe six.
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The first one is sensation.
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So this is important to understand for any and all of you
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00:14:48.520
that want to change your nervous system
link |
00:14:50.520
or to apply tools to make your nervous system work better.
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00:14:53.520
Sensation is a non-negotiable element
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00:14:56.160
of your nervous system.
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00:14:57.380
You have neurons in your eye that perceive
link |
00:14:59.680
certain colors of light and certain directions of movement.
link |
00:15:03.080
You have neurons in your skin
link |
00:15:05.060
that perceive particular kinds of touch,
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00:15:07.580
like light touch or firm touch or painful touch.
link |
00:15:10.920
You have neurons in your ears that perceive certain sounds.
link |
00:15:15.000
Your entire experience of life is filtered
link |
00:15:19.720
by these what we call sensory receptors,
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00:15:22.480
if you want to know what the name is.
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00:15:24.760
So this always raises an interesting question.
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00:15:26.720
People ask, well, is there much more out there?
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00:15:29.380
Is there a lot more happening in the world
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00:15:31.560
that I'm not experiencing or that humans aren't experiencing?
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00:15:35.560
And the answer of course is yes.
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00:15:37.440
There are many species on this planet
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00:15:39.200
that are perceiving things that we will never perceive
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00:15:42.100
unless we apply technology.
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00:15:44.480
The best example I could think of off the top of my head
link |
00:15:48.160
would be something like infrared vision.
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00:15:50.540
There are snakes out there, pit vipers and so forth
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00:15:53.720
that can sense heat emissions from other animals.
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00:15:56.080
They don't actually see their shape.
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00:15:57.680
They sense their heat shape and their heat emissions.
link |
00:16:01.400
Humans can't do that unless of course
link |
00:16:03.280
they put on infrared goggles or something
link |
00:16:05.480
that would allow them to detect those heat emissions.
link |
00:16:08.360
There are turtles and certain species of birds
link |
00:16:11.520
that migrate long distances that can detect magnetic fields
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00:16:15.200
because they have neurons.
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00:16:16.940
Again, it's the nervous system that allows them to do this.
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00:16:20.520
So they have neurons in their nose and in their head
link |
00:16:24.320
that allow them to migrate along magnetic fields
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00:16:27.520
in order to, as amazing as this sounds,
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00:16:29.980
go from one particular location in the ocean,
link |
00:16:33.120
thousands of miles away to all aggregate
link |
00:16:37.280
on one particular beach at a particular time of year
link |
00:16:40.560
so that they can mate, lay eggs
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00:16:43.200
and then wander back off into the sea to die
link |
00:16:45.800
and then their young will eventually hatch.
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00:16:48.840
Those cute little turtles will shuffle to the ocean,
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00:16:51.800
swim off and go do the exact same thing.
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00:16:54.400
They don't migrate that distance by vision.
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00:16:56.780
They don't do it by smell.
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00:16:57.840
They do it by sensing magnetic fields, okay?
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00:17:01.180
And many other species do these incredible things.
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00:17:03.980
We don't, humans are not magnetic sensing organisms.
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00:17:07.480
We can't do that because we don't have receptors
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00:17:09.860
that sense magnetic fields.
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00:17:11.640
There are some data that maybe some humans
link |
00:17:14.160
can sense magnetic fields,
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00:17:15.840
but you should be very skeptical of anyone
link |
00:17:17.460
that's convinced that they can do that
link |
00:17:19.160
with any degree of robustness or accuracy
link |
00:17:22.260
because even the people that can do this
link |
00:17:24.560
aren't necessarily aware that they can.
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00:17:26.920
Maybe a topic for a future podcast.
link |
00:17:29.240
So we have sensation.
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00:17:30.700
Then we have perception.
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00:17:32.000
Perception is our ability to take what we're sensing
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00:17:36.160
and focus on it and make sense of it,
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00:17:39.340
to explore it, to remember it.
link |
00:17:40.960
So really perceptions are just whichever sensations
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00:17:43.560
we happen to be paying attention to at any moment.
link |
00:17:46.200
And you can do this right now.
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00:17:47.680
You can experience perception
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00:17:49.540
and the difference between perception
link |
00:17:51.080
and sensation very easily.
link |
00:17:53.280
If for instance, I tell you to pay attention
link |
00:17:56.520
to the contact of your feet, the bottoms of your feet
link |
00:17:59.360
with whatever surface they happen to be in contact with,
link |
00:18:01.880
maybe it's shoes, maybe it's the floor.
link |
00:18:04.600
If your feet are up, maybe it's air.
link |
00:18:07.160
The moment you place your,
link |
00:18:09.040
what we call the spotlight of attention
link |
00:18:10.840
or the spotlight of perception on your feet,
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00:18:13.160
you are now perceiving what was happening there,
link |
00:18:15.840
what was being sensed there.
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00:18:18.120
The sensation was happening all along, however.
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00:18:20.840
So while sensation is not negotiable,
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00:18:24.760
you can't change your receptors
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00:18:26.280
unless you adopt some new technology.
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00:18:28.720
Perception is under the control of your attention.
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00:18:32.160
And the way to think about attention
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00:18:33.720
is it's like a spotlight, except it's not one spotlight.
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00:18:37.040
You actually have two attentional spotlights.
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00:18:40.720
Anyone that tells you you can't multitask,
link |
00:18:43.020
tell them they're wrong.
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00:18:44.400
And if they disagree with you, tell them to contact me.
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00:18:47.440
Because in old world primates of which humans are,
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00:18:52.680
we are able to do what's called covert attention.
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00:18:55.680
We can place a spotlight of attention on something.
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00:18:58.360
For instance, something we're reading or looking at,
link |
00:19:00.760
or someone that we're listening to.
link |
00:19:02.080
And we can place a second spotlight of attention
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00:19:05.200
on something we're eating and how it tastes,
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00:19:07.360
or our child running around in the room or my dog.
link |
00:19:10.660
You can split your attention into two locations,
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00:19:13.000
but of course you can also bring your attention,
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00:19:15.920
that is your perception, to one particular location.
link |
00:19:19.440
You can dilate your attention,
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00:19:20.880
kind of like making a spotlight more diffuse,
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00:19:23.060
or you can make it more concentrated.
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00:19:25.120
This is very important to understand
link |
00:19:27.900
if you're going to think about tools
link |
00:19:29.860
to improve your nervous system,
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00:19:31.800
whether or not that tool is in the form of a chemical
link |
00:19:35.200
that you decide to take,
link |
00:19:36.260
maybe a supplement to increase some chemical in your brain,
link |
00:19:38.820
if that's your choice, or a brain machine device,
link |
00:19:43.160
or you're going to try and learn something better
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00:19:45.640
by engaging in some focus or motivated pursuit
link |
00:19:49.100
for some period of time each day.
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00:19:51.200
Attention is something that is absolutely under your control,
link |
00:19:55.340
in particular, when you're rested.
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00:19:57.800
And we'll get back to this, but when you are rested,
link |
00:20:01.880
and we'll define rest very clearly,
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00:20:04.500
you are able to direct your attention
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00:20:06.640
in very deliberate ways.
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00:20:08.060
And that's because we have something in our nervous system
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00:20:11.980
which is sort of like a two-way street.
link |
00:20:14.320
And that two-way street is a communication
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00:20:16.460
between the aspects of our nervous system
link |
00:20:18.260
that are reflexive and the aspects of our nervous system
link |
00:20:22.120
that are deliberate.
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00:20:23.480
So we all know what it's like to be reflexive.
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00:20:26.140
You go through life, you're walking.
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00:20:27.860
If you already know how to walk,
link |
00:20:29.080
you don't think about your walking, you just walk.
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00:20:31.880
And that's because the nervous system wants to pass off
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00:20:34.640
as much as it can to reflexive action.
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00:20:37.700
That's called a bottom-up processing.
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00:20:39.600
It really just means that information is flowing in
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00:20:42.420
through your senses, regardless of what you're perceiving,
link |
00:20:45.640
that information is flowing up
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00:20:46.960
and it's directing your activity.
link |
00:20:49.280
But at any moment, for instance,
link |
00:20:51.280
let's say a car screeches in front of you around the corner
link |
00:20:54.360
and you suddenly pause,
link |
00:20:55.700
you are now moving into deliberate action.
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00:20:58.440
You would start looking around in a very deliberate way.
link |
00:21:01.720
The nervous system can be reflexive in its action
link |
00:21:04.520
or it can be deliberate.
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00:21:06.240
If reflexive action tends to be what we call bottom-up,
link |
00:21:09.920
deliberate action and deliberate perceptions
link |
00:21:13.180
and deliberate thoughts are top-down.
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00:21:15.600
They require some effort and some focus,
link |
00:21:17.960
but that's the point.
link |
00:21:18.900
You can decide to focus your attention and energy
link |
00:21:21.560
on anything you want.
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00:21:22.840
You can decide to focus your behavior in any way you want,
link |
00:21:26.520
but it will always feel like it requires some effort
link |
00:21:30.600
and some strain.
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00:21:31.460
Whereas when you're in reflexive mode,
link |
00:21:32.800
just walking and talking and eating and doing your thing,
link |
00:21:35.720
it's gonna feel very easy.
link |
00:21:37.280
And that's because your nervous system basically wired up
link |
00:21:39.840
to be able to do most things easily
link |
00:21:41.880
without much metabolic demand,
link |
00:21:43.500
without consuming much energy.
link |
00:21:45.040
But the moment you try and do something very specific,
link |
00:21:48.360
you're gonna feel a sort of mental friction.
link |
00:21:50.860
It's gonna be challenging.
link |
00:21:52.440
So we've got sensations, perceptions,
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00:21:54.960
and then we've got things that we call feelings slash
link |
00:21:58.160
emotions.
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00:21:59.000
And these get a little complicated because almost all of us,
link |
00:22:02.800
I would hope all of us are familiar with things like
link |
00:22:05.640
happiness and sadness or boredom or frustration.
link |
00:22:09.800
Scientists argue like crazy,
link |
00:22:11.840
neuroscientists and psychologists and philosophers
link |
00:22:14.160
for that matter,
link |
00:22:15.000
argue like crazy about what these are and how they work.
link |
00:22:18.720
Certainly emotions and feelings are the product
link |
00:22:21.440
of the nervous system.
link |
00:22:23.020
They involve the activity of neurons.
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00:22:25.560
But as I mentioned earlier, neurons are electrically active,
link |
00:22:28.500
but they also release chemicals.
link |
00:22:30.680
And there's a certain category of chemicals
link |
00:22:33.860
that has a very profound influence on our emotional states.
link |
00:22:39.700
They're called neuromodulators.
link |
00:22:41.440
And those neuromodulators have names
link |
00:22:43.040
that probably you've heard of before.
link |
00:22:44.640
Things like dopamine and serotonin and acetylcholine,
link |
00:22:48.360
epinephrine.
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00:22:49.920
Neuromodulators are really interesting because they bias
link |
00:22:53.480
which neurons are likely to be active
link |
00:22:55.760
and which ones are likely to be inactive.
link |
00:22:58.660
A simple way to think about neuromodulators is
link |
00:23:01.200
they are sort of like playlists that you would have
link |
00:23:04.660
on any kind of device where you're gonna play
link |
00:23:06.280
particular categories of music.
link |
00:23:08.200
So for instance, dopamine,
link |
00:23:09.820
which is often discussed as the molecule of reward or joy
link |
00:23:14.920
is involved in reward.
link |
00:23:16.920
And it does tend to create a sort of upbeat mood
link |
00:23:21.220
when released in appropriate amounts in the brain.
link |
00:23:23.420
But the reason it does that is
link |
00:23:25.080
because it makes certain neurons and neural circuits
link |
00:23:29.120
as we call them more active and others less active, okay?
link |
00:23:32.920
So serotonin for instance, is a molecule that when released
link |
00:23:37.160
tends to make us feel really good with what we have,
link |
00:23:40.360
our sort of internal landscape
link |
00:23:41.940
and the resources that we have.
link |
00:23:43.640
Whereas dopamine more than being a molecule of reward
link |
00:23:46.320
is really more a molecule of motivation
link |
00:23:49.320
toward things that are outside us and that we want to pursue.
link |
00:23:53.800
And we can look at healthy conditions or situations
link |
00:23:57.480
like being in pursuit of a goal
link |
00:23:59.400
where every time we accomplish something
link |
00:24:01.240
in route to that goal, a little bit of dopamine is released
link |
00:24:03.660
and we feel more motivation, that happens.
link |
00:24:06.600
We can also look at the extreme example
link |
00:24:08.760
of something like mania,
link |
00:24:10.120
where somebody is so relentlessly in pursuit
link |
00:24:14.500
of external things like money and relationships
link |
00:24:17.560
that they're sort of in this delusional state
link |
00:24:19.960
of thinking that they have the resources that they need
link |
00:24:22.180
in order to pursue all these things when in fact they don't.
link |
00:24:24.620
So these neuromodulators can exist in normal levels,
link |
00:24:28.400
low levels, high levels.
link |
00:24:29.720
And that actually gives us a window
link |
00:24:31.480
into a very important aspect of neuroscience history
link |
00:24:34.960
that all of us are impacted by today,
link |
00:24:36.860
which is the discovery of antidepressants
link |
00:24:39.120
and so-called antipsychotics.
link |
00:24:41.080
In the 1950s, 60s, and 70s, it was discovered
link |
00:24:45.000
that there are compounds, chemicals,
link |
00:24:47.420
that can increase or decrease serotonin,
link |
00:24:50.080
that can increase or decrease dopamine.
link |
00:24:52.800
And that led to the development
link |
00:24:54.980
of most of what we call antidepressants.
link |
00:24:57.960
Now, the trick here or the problem
link |
00:25:01.000
is that most of these drugs,
link |
00:25:03.320
especially in the 1950s and 60s,
link |
00:25:05.680
they would reduce serotonin,
link |
00:25:07.040
but they would also reduce dopamine,
link |
00:25:08.720
or they would increase serotonin,
link |
00:25:10.080
but they would also increase
link |
00:25:11.440
some other neuromodulator or chemical.
link |
00:25:13.280
And that's because all these chemical systems in the body,
link |
00:25:17.300
but the neuromodulators in particular,
link |
00:25:19.440
have a lot of receptors.
link |
00:25:21.360
Now, these are different than the receptors
link |
00:25:22.800
we were talking about earlier.
link |
00:25:24.000
The receptors I'm talking about now
link |
00:25:25.360
are sort of like parking spots where dopamine is released.
link |
00:25:28.720
And if it attaches to a receptor, say on the heart,
link |
00:25:32.940
it might make the heart beat faster
link |
00:25:35.160
because there's a certain kind of receptor on the heart.
link |
00:25:37.580
Whereas if dopamine is released
link |
00:25:40.280
and goes and attaches to muscle,
link |
00:25:42.440
it might have a completely different effect on muscle.
link |
00:25:44.640
And in fact, it does.
link |
00:25:46.480
So different receptors on different organs of the body
link |
00:25:49.140
are the ways that these neuromodulators
link |
00:25:51.420
can have all these different effects
link |
00:25:53.720
on different aspects of our biology.
link |
00:25:55.860
This is most salient in the example
link |
00:25:58.840
of some of the antidepressants
link |
00:26:01.160
that have sexual side effects,
link |
00:26:03.600
or that blunt appetite, or that blunt motivation.
link |
00:26:06.880
You know, many of these which increase serotonin
link |
00:26:10.280
can be very beneficial for people.
link |
00:26:12.320
It can elevate their mood, it can make them feel better,
link |
00:26:14.760
but they also, if the doses are too high,
link |
00:26:18.000
or if that particular drug isn't right for somebody,
link |
00:26:20.600
that person experiences challenges with motivation,
link |
00:26:23.360
or appetite, or libido,
link |
00:26:24.800
because serotonin is binding to receptors
link |
00:26:27.800
in the areas of the brain
link |
00:26:28.680
that control those other things as well.
link |
00:26:31.160
So we talked about sensation, we talked about perception.
link |
00:26:34.440
When we talk about feelings,
link |
00:26:35.480
we have to consider these neuromodulators.
link |
00:26:38.000
And we have to consider also
link |
00:26:39.260
that feelings and emotions are contextual.
link |
00:26:42.720
In some cultures, showing a lot of joy
link |
00:26:45.600
or a lot of sadness is entirely appropriate.
link |
00:26:47.860
In other cultures, it's considered inappropriate.
link |
00:26:50.440
So I don't think it's fair to say
link |
00:26:51.820
that there's a sadness circuit or area of the brain,
link |
00:26:55.180
or a happiness circuit or area of the brain.
link |
00:26:57.520
However, it is fair to say that certain chemicals
link |
00:27:01.420
and certain brain circuits tend to be active
link |
00:27:04.040
when we are in motivated states,
link |
00:27:05.640
tend to be active when we are in non-motivated, lazy states,
link |
00:27:09.360
tend to be active when we are focused,
link |
00:27:11.600
and tend to be active when we are not focused.
link |
00:27:15.680
I want to emphasize also that emotions
link |
00:27:19.240
are something that we generally feel
link |
00:27:21.980
are not under our control.
link |
00:27:23.220
We feel like the kind of guys are up within us
link |
00:27:25.080
and they just kind of happen to us.
link |
00:27:27.180
And that's because they are somewhat reflexive.
link |
00:27:29.880
We don't really set out
link |
00:27:31.400
with a deliberate thought to be happy
link |
00:27:33.040
or deliberate thought to be sad.
link |
00:27:34.780
We tend to experience them
link |
00:27:36.120
in kind of a passive reflexive way.
link |
00:27:38.840
And that brings us to the next thing, which are thoughts.
link |
00:27:41.800
Thoughts are really interesting
link |
00:27:43.000
because in many ways they're like perceptions,
link |
00:27:45.720
except that they draw on not just what's happening
link |
00:27:48.340
in the present, but also things we remember from the past
link |
00:27:52.280
and things that we anticipate about the future.
link |
00:27:55.080
The other thing about thoughts that's really interesting
link |
00:27:57.020
is that thoughts can be both reflexive,
link |
00:28:00.760
they can just be occurring all the time,
link |
00:28:02.640
sort of like pop-up windows
link |
00:28:04.380
on a poorly filtered web browser,
link |
00:28:06.920
or they can be deliberate.
link |
00:28:08.440
We can decide to have a thought.
link |
00:28:10.040
In fact, right now you could decide to have a thought
link |
00:28:12.080
just like you would decide to write something out
link |
00:28:13.920
on a piece of paper.
link |
00:28:15.280
You could decide that you're listening to a podcast,
link |
00:28:17.640
that you are in a particular location.
link |
00:28:19.840
You're not just paying attention to what's happening,
link |
00:28:21.520
you're directing your thought process.
link |
00:28:23.760
And a lot of people don't understand
link |
00:28:25.520
or at least appreciate that the thought patterns
link |
00:28:27.740
and the neural circuits that underlie thoughts
link |
00:28:30.560
can actually be controlled in this deliberate way.
link |
00:28:33.680
And then finally, there are actions.
link |
00:28:36.340
Actions or behaviors are perhaps the most important aspect
link |
00:28:40.160
to our nervous system.
link |
00:28:41.560
Because first of all, our behaviors are actually
link |
00:28:46.040
the only thing that are gonna create any fossil record
link |
00:28:49.200
of our existence.
link |
00:28:50.720
After we die, the nervous system deteriorates,
link |
00:28:53.120
our skeleton will remain, but it's in the moment
link |
00:28:57.000
of experiencing something very joyful
link |
00:28:59.520
or something very sad.
link |
00:29:01.520
It can feel so all encompassing that we actually think
link |
00:29:05.880
that it has some meaning beyond that moment.
link |
00:29:08.160
But actually for humans, and I think for all species,
link |
00:29:12.840
the sensations, the perceptions and the thoughts
link |
00:29:16.480
and the feelings that we have in our lifespan,
link |
00:29:19.760
none of that is actually carried forward
link |
00:29:22.700
except the ones that we take and we convert
link |
00:29:25.760
into actions such as writing, actions such as words,
link |
00:29:30.440
actions such as engineering new things.
link |
00:29:32.680
And so the fossil record of our species
link |
00:29:35.540
and of each one of us is really through action.
link |
00:29:39.040
And that in part is why so much of our nervous system
link |
00:29:43.320
is devoted to converting sensation, perceptions,
link |
00:29:46.840
feelings, and thoughts into actions.
link |
00:29:49.660
In fact, the great neuroscientist or physiologist,
link |
00:29:54.360
Sherrington won a Nobel Prize for his work
link |
00:29:57.320
in mapping some of the circuitry,
link |
00:29:59.960
the connections between nerve cells
link |
00:30:01.480
that give rise to movement.
link |
00:30:03.420
And he said, movement is the final common pathway.
link |
00:30:07.160
The other way to think about it is that one of the reasons
link |
00:30:10.360
that our central nervous system, our brain and spinal cord
link |
00:30:13.120
include this stuff in our skull,
link |
00:30:14.940
but also connects so heavily to the body
link |
00:30:17.120
is because most everything that we experience,
link |
00:30:19.820
including our thoughts and feelings was really designed
link |
00:30:22.960
to either impact our behavior or not.
link |
00:30:25.920
And the fact that thoughts allow us to reach into the past
link |
00:30:28.760
and anticipate the future and not just experience
link |
00:30:30.980
what's happening in the moment gave rise
link |
00:30:33.320
to an incredible capacity for us to engage in behaviors
link |
00:30:37.100
that are not just for the moment.
link |
00:30:38.840
They're based on things that we know from the past
link |
00:30:40.920
and that we would like to see in the future.
link |
00:30:43.960
And this aspect to our nervous system of creating movement
link |
00:30:47.800
occurs through some very simple pathways.
link |
00:30:50.480
The reflexive pathway basically includes areas
link |
00:30:54.140
of the brainstem we call central pattern generators.
link |
00:30:57.000
When you walk, provided you already know how to walk,
link |
00:31:00.040
you are basically walking
link |
00:31:03.100
because you have these central pattern generators,
link |
00:31:05.000
groups of neurons that generate right foot, left foot,
link |
00:31:07.160
right foot, left foot kind of movement.
link |
00:31:09.040
However, when you decide to move
link |
00:31:10.600
in a particular deliberate way
link |
00:31:12.160
that requires a little more attention,
link |
00:31:14.240
you start to engage areas of your brain
link |
00:31:17.520
for top-down processing where your forebrain works
link |
00:31:21.160
from the top down to control those central pattern generators
link |
00:31:24.600
so that maybe it's right foot, right foot, left foot,
link |
00:31:26.820
right foot, right foot, left foot
link |
00:31:27.960
if maybe you're hiking along some rocks or something
link |
00:31:30.120
and you have to engage in that kind of movement.
link |
00:31:32.560
So movement is just like thoughts,
link |
00:31:36.000
can be either reflexive or deliberate.
link |
00:31:39.440
And when we talk about deliberate,
link |
00:31:41.000
I want to be very specific about how your brain works
link |
00:31:44.020
in the deliberate way because it gives rise
link |
00:31:46.340
to a very important feature of the nervous system
link |
00:31:49.140
that we're going to talk about next
link |
00:31:50.240
which is your ability to change your nervous system.
link |
00:31:53.240
And what I'd like to center on for a second is this notion
link |
00:31:56.360
of what does it mean for the nervous system
link |
00:31:58.960
to do something deliberately?
link |
00:32:01.060
Well, when you do something deliberately,
link |
00:32:03.480
you pay attention, you are bringing your perception
link |
00:32:06.680
to an analysis of three things.
link |
00:32:09.460
Duration, how long something is going to take
link |
00:32:12.680
or it should be done, path, what you should be doing,
link |
00:32:16.400
and outcome.
link |
00:32:17.320
If you do something for a given length of time,
link |
00:32:19.360
what's going to happen?
link |
00:32:20.600
Now, when you're walking down the street or you're eating
link |
00:32:22.540
or you're just talking reflexively,
link |
00:32:24.200
you're not doing this what I call DPO,
link |
00:32:26.200
duration, path, outcome type of deliberate function
link |
00:32:29.400
in your brain and nervous system.
link |
00:32:31.280
But the moment you decide to learn something
link |
00:32:34.080
or to resist speaking or to speak up
link |
00:32:37.280
when you would rather be quiet,
link |
00:32:39.400
anytime you're deliberately forcing yourself
link |
00:32:42.240
over a threshold, you're engaging these brain circuits
link |
00:32:46.480
and these nervous system circuits
link |
00:32:48.360
that suddenly make it feel as if something is challenging,
link |
00:32:52.120
something has changed.
link |
00:32:53.600
Well, what's changed?
link |
00:32:54.720
What's changed is that when you engage in this duration,
link |
00:32:57.620
path and outcome type of thinking or behavior
link |
00:33:00.840
or way of being, you start to recruit these neuromodulators
link |
00:33:06.020
that are released from particular areas of your brain
link |
00:33:08.320
and also it turns out from your body,
link |
00:33:09.920
and they start queuing to your nervous system,
link |
00:33:12.240
something's different, something's different now
link |
00:33:14.160
about what I'm doing,
link |
00:33:15.280
something's different about what I'm feeling.
link |
00:33:17.380
Let's give an example where perhaps somebody says something
link |
00:33:21.160
that's triggering to you, you don't like it,
link |
00:33:23.320
and you know you shouldn't respond.
link |
00:33:25.340
You feel like, oh, I shouldn't respond,
link |
00:33:27.000
I shouldn't respond, I shouldn't respond.
link |
00:33:28.400
You're actively suppressing your behavior
link |
00:33:30.840
through top-down processing.
link |
00:33:33.640
Your forebrain is actually preventing you
link |
00:33:35.580
from saying the thing that you know you shouldn't say
link |
00:33:38.320
or that maybe you should wait to say or say
link |
00:33:40.080
in a different form.
link |
00:33:41.560
This feels like agitation and stress
link |
00:33:43.760
because you're actually suppressing a circuit.
link |
00:33:46.120
We actually can see examples of what happens
link |
00:33:48.420
when you're not doing this well.
link |
00:33:51.100
Some of the examples come from children.
link |
00:33:53.960
If you look at young children,
link |
00:33:55.440
they don't have the forebrain circuitry
link |
00:33:57.900
to engage in this top-down processing
link |
00:33:59.880
until they reach age 22, even 25.
link |
00:34:03.320
But in young children, you see this in a really robust way.
link |
00:34:06.920
You'll see they'll be rocking back and forth.
link |
00:34:08.720
It's hard for them to sit still
link |
00:34:10.000
because those central pattern generators
link |
00:34:11.960
are constantly going in the background,
link |
00:34:13.400
whereas adults can sit still.
link |
00:34:15.400
A kid sees a piece of candy that it wants
link |
00:34:17.600
and will just reach out and grab it,
link |
00:34:19.660
whereas an adult probably would ask
link |
00:34:21.580
if they could have a piece
link |
00:34:22.420
or wait until they were offered a piece in most cases.
link |
00:34:25.560
People that have damage to the certain areas
link |
00:34:28.000
of the frontal lobes don't have this kind of restriction.
link |
00:34:31.120
They'll just blurt things out.
link |
00:34:32.560
They'll just say things.
link |
00:34:33.480
We all know people like this.
link |
00:34:34.960
Impulsivity is a lack of top-down control,
link |
00:34:38.960
a lack of top-down processing.
link |
00:34:41.120
The other thing that will turn off the forebrain
link |
00:34:43.160
and make it harder to top-down processing
link |
00:34:45.280
is a couple of drinks containing alcohol.
link |
00:34:48.560
The removal of inhibition
link |
00:34:50.380
is actually a removal of neural inhibition
link |
00:34:53.560
of nerve cells suppressing the activity
link |
00:34:56.080
of other nerve cells.
link |
00:34:57.440
And so when you look at people
link |
00:34:59.320
that have damage to their frontal lobes,
link |
00:35:01.120
or you look at puppies, or you look at young children,
link |
00:35:04.080
everything's a stimulus.
link |
00:35:05.440
Everything is a potential interaction for them,
link |
00:35:07.420
and they have a very hard time
link |
00:35:08.860
restricting their behavior and their speech.
link |
00:35:11.520
So a lot of the motor system
link |
00:35:13.920
is designed to just work in a reflexive way.
link |
00:35:16.840
And then when we decide we want to learn something
link |
00:35:18.760
or do something or not do something,
link |
00:35:21.180
we have to engage in this top-down restriction,
link |
00:35:23.680
and it feels like agitation
link |
00:35:25.280
because it's accompanied by the release
link |
00:35:27.160
of a neuromodulator called norepinephrine,
link |
00:35:30.080
which in the body we call adrenaline,
link |
00:35:32.080
and it actually makes us feel agitated.
link |
00:35:34.320
So for those of you that are trying to learn something new
link |
00:35:36.980
or to learn to suppress your responses
link |
00:35:39.120
or be more deliberate and careful in your responses,
link |
00:35:43.140
that is going to feel challenging for a particular reason.
link |
00:35:46.480
It's going to feel challenging
link |
00:35:47.540
because the chemicals in your body
link |
00:35:49.160
that are released in association with that effort
link |
00:35:52.420
are designed to make you feel kind of agitated.
link |
00:35:55.640
That low-level tremor that sometimes people feel
link |
00:35:57.620
when they're really, really angry
link |
00:35:59.060
is actually a chemically induced low-level tremor.
link |
00:36:02.400
And it's the, what I call limbic friction.
link |
00:36:04.920
There's an area of your brain that's involved
link |
00:36:06.380
in our more primitive reflexive responses
link |
00:36:08.560
called the limbic system.
link |
00:36:09.960
And the frontal cortex is in a friction.
link |
00:36:12.760
It's in a tug-of-war with that system all the time,
link |
00:36:16.000
unless of course you have damage to the frontal lobe
link |
00:36:18.240
or you've had too much to drink or something,
link |
00:36:19.760
in which case you tend to just say and do whatever.
link |
00:36:22.320
And so this is really important to understand
link |
00:36:25.460
because if you want to understand neuroplasticity,
link |
00:36:28.720
you want to understand how to shape your behavior,
link |
00:36:30.740
how to shape your thinking,
link |
00:36:31.840
how to change how you're able to perform in any context,
link |
00:36:36.700
the most important thing to understand
link |
00:36:38.600
is that it requires top-down processing.
link |
00:36:41.760
It requires this feeling of agitation.
link |
00:36:44.760
In fact, I would say that agitation and strain
link |
00:36:47.260
is the entry point to neuroplasticity.
link |
00:36:50.240
So let's take a look at what neuroplasticity is.
link |
00:36:52.920
Let's explore it not as the way it's normally talked about
link |
00:36:56.000
in modern culture as a neuroplasticity.
link |
00:36:58.720
Plasticity is great.
link |
00:37:00.360
What exactly do people mean?
link |
00:37:02.000
Plasticity itself is just a process by which neurons
link |
00:37:05.400
can change their connections in the way they work
link |
00:37:07.740
so that you can go from things
link |
00:37:10.720
being very challenging and deliberate,
link |
00:37:13.480
requiring a lot of effort and strain
link |
00:37:15.480
to them being reflexive.
link |
00:37:17.040
And typically when we hear about plasticity,
link |
00:37:18.800
we're thinking about positive
link |
00:37:19.920
or what I call adaptive plasticity.
link |
00:37:22.360
A lot of plasticity can be induced,
link |
00:37:24.000
for instance, by brain damage,
link |
00:37:25.440
but that's generally not the kind of plasticity
link |
00:37:27.240
that we want.
link |
00:37:28.160
So when I say plasticity, unless I say otherwise,
link |
00:37:30.840
I mean adaptive plasticity.
link |
00:37:32.680
And in particular, most of the neuroplasticity
link |
00:37:35.680
that people want is self-directed plasticity
link |
00:37:38.600
because if there's one truism to neuroplasticity,
link |
00:37:41.440
it's that from birth until about age 25,
link |
00:37:45.680
the brain is incredibly plastic.
link |
00:37:47.640
Kids are learning all sorts of things,
link |
00:37:49.660
but they can learn it passively.
link |
00:37:51.380
They don't have to work too hard or focus too hard,
link |
00:37:54.800
although focus helps, to learn new things,
link |
00:37:57.720
acquire new languages, acquire new skills.
link |
00:38:00.120
But if you're an adult
link |
00:38:01.080
and you want to change your neural circuitry
link |
00:38:03.280
at the level of emotions or behavior or thoughts
link |
00:38:05.740
or anything really,
link |
00:38:07.340
you absolutely need to ask two important questions.
link |
00:38:11.400
One, what particular aspect of my nervous system
link |
00:38:16.560
am I trying to change?
link |
00:38:18.360
Meaning, am I trying to change my emotions
link |
00:38:20.440
or my perceptions, my sensations,
link |
00:38:22.480
and which ones are available for me to change?
link |
00:38:24.840
And then the second question is,
link |
00:38:26.600
how are you going to go about that?
link |
00:38:28.260
What is the structure of a regimen
link |
00:38:31.680
to engage neuroplasticity?
link |
00:38:33.360
And it turns out that the answer to that second question
link |
00:38:36.380
is governed by how awake or how sleepy we are.
link |
00:38:40.080
So let's talk about that next.
link |
00:38:41.620
Neuroplasticity is the ability for these connections
link |
00:38:44.500
in the brain and body to change in response to experience.
link |
00:38:47.640
And what's so incredible
link |
00:38:48.800
about the human nervous system in particular
link |
00:38:51.020
is that we can direct our own neural changes.
link |
00:38:54.100
We can decide that we want to change our brain.
link |
00:38:57.440
In other words, our brain can change itself
link |
00:38:59.520
and our nervous system can change itself.
link |
00:39:01.400
And the same can't be said for other organs of the body.
link |
00:39:04.280
Even though our other organs of the body
link |
00:39:06.140
have some ability to change, they can't direct it.
link |
00:39:10.000
They can't think and decide,
link |
00:39:11.420
oh, you know, your gut doesn't say,
link |
00:39:12.820
oh, you know, I want to be able to digest spicy foods better.
link |
00:39:15.500
So I'm going to rearrange the connections
link |
00:39:17.480
to be able to do that.
link |
00:39:18.360
Whereas your brain can decide
link |
00:39:20.120
that you want to learn a language
link |
00:39:21.660
or you want to be less emotionally reactive
link |
00:39:24.040
or more emotionally engaged.
link |
00:39:25.740
And you can undergo a series of steps
link |
00:39:28.040
that will allow your brain to make those changes
link |
00:39:31.020
so that eventually it becomes reflexive for you to do that,
link |
00:39:34.180
which is absolutely incredible.
link |
00:39:37.120
For a long time, it was thought that neuroplasticity
link |
00:39:40.300
was the unique gift of young animals and humans,
link |
00:39:43.360
that it could only occur when we're young.
link |
00:39:45.140
And in fact, the young brain is incredibly plastic.
link |
00:39:48.120
Children can learn three languages
link |
00:39:49.920
without an accent reflexively,
link |
00:39:52.120
whereas adults, it's very challenging.
link |
00:39:54.760
It takes a lot more effort and strain,
link |
00:39:56.440
a lot more of that duration path outcome kind of thinking
link |
00:39:59.160
in order to achieve those plastic changes.
link |
00:40:02.880
We now know, however, that the adult brain can change
link |
00:40:06.360
in response to experience.
link |
00:40:08.200
Nobel prizes were given for the understanding
link |
00:40:11.840
that the young brain can change very dramatically.
link |
00:40:14.360
I think one of the most extreme examples would be
link |
00:40:17.020
for people that are born blind from birth,
link |
00:40:19.980
they use the area of their brain
link |
00:40:21.460
that normally would be used for visualizing objects
link |
00:40:24.640
and colors and things outside of them for braille reading.
link |
00:40:28.180
In brain imaging studies, it's been shown that, you know,
link |
00:40:31.200
people who are blind from birth, when they braille read,
link |
00:40:33.400
the area of the brain that would normally light up,
link |
00:40:36.760
if you will, for vision, lights up for braille reading.
link |
00:40:40.960
So that real estate is reallocated
link |
00:40:43.560
for an entirely different function.
link |
00:40:45.300
If someone is made blind in adulthood,
link |
00:40:49.560
it's unlikely that their entire visual brain
link |
00:40:52.080
will be taken over by the areas of the brain
link |
00:40:55.500
they're responsible for touch.
link |
00:40:56.840
However, there's some evidence that areas of the brain
link |
00:41:00.180
that are involved in hearing and touch
link |
00:41:01.580
can kind of migrate into that area.
link |
00:41:04.140
And there's a lot of interest now in trying to figure out
link |
00:41:06.500
how more plasticity can be induced in adulthood,
link |
00:41:10.060
more positive plasticity.
link |
00:41:12.380
And in order to understand that process,
link |
00:41:15.620
we really have to understand something
link |
00:41:17.540
that might at first seem totally divorced
link |
00:41:19.540
from neuroplasticity,
link |
00:41:20.880
but actually lies at the center of neuroplasticity.
link |
00:41:23.900
And for any of you that are interested
link |
00:41:25.420
in changing your nervous system
link |
00:41:27.020
so that something that you want
link |
00:41:28.940
can go from being very hard
link |
00:41:30.780
or seem almost impossible and out of reach
link |
00:41:33.020
to being very reflexive,
link |
00:41:34.900
this is especially important to pay attention to.
link |
00:41:39.380
Plasticity in the adult human nervous system
link |
00:41:42.140
is gated, meaning it is controlled by neuromodulators.
link |
00:41:47.640
These things that we talked about earlier,
link |
00:41:49.620
dopamine, serotonin,
link |
00:41:51.660
and one in particular called acetylcholine
link |
00:41:55.320
are what open up plasticity.
link |
00:41:57.940
They literally unveil plasticity
link |
00:42:00.200
and allow brief periods of time
link |
00:42:01.640
in which whatever information,
link |
00:42:03.700
whatever thing we're sensing or perceiving or thinking,
link |
00:42:07.180
whatever emotions we feel
link |
00:42:09.020
can literally be mapped in the brain
link |
00:42:11.260
such that later it will become much easier
link |
00:42:14.240
for us to experience and feel that thing.
link |
00:42:16.920
Now this has a dark side and a positive side.
link |
00:42:19.920
The dark side is it's actually very easy
link |
00:42:22.240
to get neuroplasticity as an adult
link |
00:42:24.540
through traumatic or terrible or challenging experiences.
link |
00:42:28.380
But the important question is to say, why is that?
link |
00:42:31.720
And the reason that's the case
link |
00:42:33.660
is because when something very bad happens,
link |
00:42:37.260
there's the release of two sets of neuromodulators
link |
00:42:40.220
in the brain,
link |
00:42:41.620
epinephrine, which tends to make us feel alert and agitated,
link |
00:42:45.260
which is associated with most bad circumstances,
link |
00:42:48.180
and acetylcholine, which tends to create
link |
00:42:50.780
a even more intense and focused perceptual spotlight.
link |
00:42:55.060
Remember earlier we were talking about perception
link |
00:42:57.180
and how it's kind of like a spotlight.
link |
00:42:58.820
Acetylcholine makes that light particularly bright
link |
00:43:01.480
and particularly restricted to one region of our experience.
link |
00:43:06.100
And it does that by making certain neurons in our brain
link |
00:43:09.660
and body active much more than all the rest.
link |
00:43:14.660
So acetylcholine is sort of like a highlighter marker
link |
00:43:18.180
upon which neuroplasticity then comes in later
link |
00:43:21.780
and says, wait, which neurons were active
link |
00:43:23.820
in this particularly alerting phase
link |
00:43:27.260
of whatever day or night,
link |
00:43:29.380
whenever this thing happened to happen.
link |
00:43:30.800
So the way it works is this,
link |
00:43:31.900
you can think of epinephrine as creating this alertness
link |
00:43:35.320
and this kind of unbelievable level of increased attention
link |
00:43:38.980
compared to what you were experiencing before.
link |
00:43:40.660
And you can think of acetylcholine as being the molecule
link |
00:43:44.880
that highlights whatever happens
link |
00:43:47.660
during that period of heightened alertness.
link |
00:43:50.440
So just to be clear,
link |
00:43:52.080
it's epinephrine creates the alertness
link |
00:43:54.760
that's coming from a subset of neurons in the brainstem
link |
00:43:56.820
if you're interested,
link |
00:43:57.940
and acetylcholine coming from an area of the forebrain
link |
00:44:01.800
is tagging or marking the neurons
link |
00:44:04.620
that are particularly active
link |
00:44:06.000
during this heightened level of alertness.
link |
00:44:09.360
Now that marks the cells,
link |
00:44:11.100
the neurons and the synapses for strengthening,
link |
00:44:14.500
for becoming more likely to be active in the future,
link |
00:44:18.540
even without us thinking about it, okay?
link |
00:44:21.760
So in bad circumstances,
link |
00:44:24.300
this all happens without us having to do much.
link |
00:44:27.600
When we want something to happen, however,
link |
00:44:30.040
we wanna learn a new language,
link |
00:44:31.540
we want to learn a new skill,
link |
00:44:33.180
we wanna become more motivated.
link |
00:44:35.360
What do we know for certain?
link |
00:44:36.520
We know that that process of getting neuroplasticity
link |
00:44:40.320
so that we have more focus, more motivation,
link |
00:44:42.480
absolutely requires the release of epinephrine.
link |
00:44:46.740
We have to have alertness in order to have focus,
link |
00:44:50.080
and we have to have focus
link |
00:44:51.880
in order to direct those plastic changes
link |
00:44:54.800
to particular parts of our nervous system.
link |
00:44:57.680
Now this has immense implications
link |
00:45:00.600
in thinking about the various tools,
link |
00:45:03.200
whether or not those are chemical tools or machine tools,
link |
00:45:06.520
or just self-induced regimens of how long
link |
00:45:10.100
or how intensely you're going to focus
link |
00:45:11.800
in order to get neuroplasticity.
link |
00:45:15.600
But there's another side to it.
link |
00:45:18.100
The dirty secret of neuroplasticity
link |
00:45:19.920
is that no neuroplasticity occurs
link |
00:45:22.600
during the thing you're trying to learn,
link |
00:45:24.760
during the terrible event, during the great event,
link |
00:45:28.580
during the thing that you're really trying to shape
link |
00:45:31.140
and learn nothing is actually changing
link |
00:45:34.320
between the neurons that is going to last.
link |
00:45:37.160
All the neuroplasticity, the strengthening of the synapses,
link |
00:45:41.600
the addition in some cases of new nerve cells,
link |
00:45:44.620
or at least connections between nerve cells,
link |
00:45:47.440
all of that occurs at a very different phase of life,
link |
00:45:50.900
which is when we are in sleep and non-sleep deep rest.
link |
00:45:54.880
And so neuroplasticity,
link |
00:45:56.280
which is the kind of holy grail of human experience of,
link |
00:45:59.440
you know, this is the new year
link |
00:46:00.460
and everyone's thinking new year's resolutions.
link |
00:46:02.280
And right now, perhaps everything's organized
link |
00:46:04.920
and people are highly motivated,
link |
00:46:06.400
but what happens in March or April or May?
link |
00:46:09.160
Well, that all depends on how much attention and focus
link |
00:46:12.460
one can continually bring
link |
00:46:14.200
to whatever it is they're trying to learn.
link |
00:46:16.080
So much so that agitation and a feeling of strain
link |
00:46:19.320
are actually required for this process of neuroplasticity
link |
00:46:23.400
to get triggered.
link |
00:46:24.640
But the actual rewiring occurs during periods of sleep
link |
00:46:27.540
and non-sleep deep rest.
link |
00:46:30.640
There's a study published last year
link |
00:46:32.020
that's particularly relevant here that I wanna share,
link |
00:46:35.280
was not done by my laboratory,
link |
00:46:37.300
that showed that 20 minutes of deep rest,
link |
00:46:41.280
this is not deep sleep,
link |
00:46:42.920
but essentially doing something very hard and very intense,
link |
00:46:46.840
and then taking 20 minutes afterwards,
link |
00:46:49.160
immediately afterwards,
link |
00:46:50.520
to deliberately turn off the deliberate focused thinking
link |
00:46:54.540
and engagement actually accelerated neuroplasticity.
link |
00:46:58.460
There's another study that's just incredible,
link |
00:47:00.680
and we're gonna go into this in a future episode
link |
00:47:03.040
of the podcast, Not Too Long From Now,
link |
00:47:05.160
that showed that if people are learning a particular skill,
link |
00:47:10.160
it could be a language skill or a motor skill,
link |
00:47:12.800
and they hear a tone just playing in the background,
link |
00:47:16.480
the tone is playing periodically through the background,
link |
00:47:18.520
like just a bell, in deep sleep, if that bell is played,
link |
00:47:24.560
learning is much faster for the thing
link |
00:47:26.700
that they were learning while they were awake.
link |
00:47:29.200
It somehow cues the nervous system in sleep,
link |
00:47:32.840
it doesn't even have to be in dreaming,
link |
00:47:34.560
that something that happened in the waking phase
link |
00:47:38.000
was especially important,
link |
00:47:39.480
so much so that that bell is sort of a Pavlovian cue,
link |
00:47:43.600
it's sort of a reminder to the sleeping brain,
link |
00:47:46.320
oh, you need to remember what it is that you were learning
link |
00:47:48.600
at that particular time of day,
link |
00:47:49.680
and the learning rates and the rates of retention,
link |
00:47:52.840
meaning how much people can remember
link |
00:47:54.220
from the thing they learned,
link |
00:47:55.400
are significantly higher under those conditions.
link |
00:47:58.820
So I'm gonna talk about how to apply all this knowledge
link |
00:48:01.520
in a little bit more in this podcast episode,
link |
00:48:04.100
but also in future episodes,
link |
00:48:05.920
but it really speaks to the really key importance
link |
00:48:10.160
of sleep and focus,
link |
00:48:12.600
these two opposite ends of our attentional state.
link |
00:48:15.760
When we're in sleep, these DPOs,
link |
00:48:17.760
duration, path, and outcome analysis are impossible,
link |
00:48:20.400
we just can't do that,
link |
00:48:21.800
we are only in relation to what's happening inside of us.
link |
00:48:25.420
So sleep is key,
link |
00:48:27.380
also key are periods of non-sleep deep rest
link |
00:48:30.080
where we're turning off our analysis
link |
00:48:31.960
of duration, path, and outcome,
link |
00:48:33.580
in particular for the thing
link |
00:48:35.160
that we were just trying to learn,
link |
00:48:37.240
and we're in this kind of liminal state
link |
00:48:40.240
where our attention is kind of drifting all over,
link |
00:48:42.480
it turns out that's very important for the consolidation,
link |
00:48:45.120
for the changes between the nerve cells
link |
00:48:47.360
that will allow what we were trying to learn
link |
00:48:49.580
to go from being deliberate and hard and stressful
link |
00:48:53.120
and a strain to easy and reflexive.
link |
00:48:58.140
This also points to how different people,
link |
00:49:01.240
including many modern clinicians,
link |
00:49:03.120
are thinking about how to prevent bad circumstances,
link |
00:49:05.840
traumas from routing their way
link |
00:49:07.680
into our nervous system permanently.
link |
00:49:09.280
It says that you might wanna interfere
link |
00:49:11.540
with certain aspects of brain states
link |
00:49:14.180
that are away from the bad thing that happened,
link |
00:49:17.520
the brain states that happened the next day
link |
00:49:19.560
or the next month or the next year.
link |
00:49:21.800
And also I wanna make sure
link |
00:49:24.760
that I pay attention to the fact that for many of you,
link |
00:49:27.220
you're thinking about neuroplasticity,
link |
00:49:28.600
not just in changing your nervous system
link |
00:49:30.880
to add something new,
link |
00:49:32.360
but to also get rid of things that you don't like, right?
link |
00:49:35.880
That you wanna forget bad experiences
link |
00:49:38.080
or at least remove the emotional contingency
link |
00:49:40.500
of a bad relationship
link |
00:49:41.920
or a bad relationship to some thing or some person
link |
00:49:45.020
or some event, learning to fear certain things less,
link |
00:49:49.340
to eliminate a phobia, to erase a trauma.
link |
00:49:52.760
The memories themselves don't get erased.
link |
00:49:54.980
I'm sorry to say that the memories themselves get erased,
link |
00:49:57.760
but the emotional load of memories can be reduced.
link |
00:50:00.640
And there are a number of different ways
link |
00:50:01.920
that that can happen,
link |
00:50:03.180
but they all require this thing
link |
00:50:04.640
that we're calling neuroplasticity.
link |
00:50:07.520
We're gonna have a large number of discussions
link |
00:50:09.920
about neuroplasticity in depth.
link |
00:50:12.020
But the most important thing to understand
link |
00:50:14.440
is that it is indeed a two-phase process.
link |
00:50:17.420
What governs the transition between alert and focused
link |
00:50:21.240
and these deep rest and deep sleep states
link |
00:50:24.800
is a system in our brain and body,
link |
00:50:27.240
a certain aspect of the nervous system
link |
00:50:28.860
called the autonomic nervous system.
link |
00:50:31.600
And it is immensely important to understand
link |
00:50:33.800
how this autonomic nervous system works.
link |
00:50:36.240
It has names like the sympathetic nervous system
link |
00:50:38.400
and parasympathetic nervous system,
link |
00:50:39.720
which frankly are complicated names
link |
00:50:42.400
because they're a little bit misleading.
link |
00:50:43.760
Sympathetic is the one that's associated
link |
00:50:45.580
with more alertness.
link |
00:50:46.420
Parasympathetic is the one that's associated
link |
00:50:48.080
with more calmness.
link |
00:50:49.760
And it gets really misleading
link |
00:50:51.120
because the sympathetic nervous system sounds like sympathy
link |
00:50:54.340
and then people think it's related to calm.
link |
00:50:55.880
I'm gonna call it the alertness system
link |
00:50:57.440
and the calmness system,
link |
00:50:59.200
because even though sympathetic and parasympathetic
link |
00:51:02.680
are sometimes used, people really get confused.
link |
00:51:05.400
So the way to think about the autonomic nervous system
link |
00:51:08.700
and the reason it's important for every aspect of your life,
link |
00:51:11.940
but in particular for neuroplasticity
link |
00:51:13.920
and engaging in these focused states
link |
00:51:15.960
and then these defocused states
link |
00:51:17.620
is that it works sort of like a seesaw.
link |
00:51:19.880
Every 24 hours, we're all familiar with the fact
link |
00:51:23.000
that when we wake up in the morning,
link |
00:51:24.180
we might be a little bit groggy,
link |
00:51:25.320
but then generally we're more alert.
link |
00:51:26.960
And then as evening comes around,
link |
00:51:29.140
we tend to become a little more relaxed and sleepy.
link |
00:51:31.200
And eventually at some point at night, we go to sleep.
link |
00:51:33.640
So we go from alert to deeply calm.
link |
00:51:36.880
And as we do that, we go from an ability
link |
00:51:38.800
to engage in these very focused
link |
00:51:41.120
duration path outcome types of analysis
link |
00:51:43.560
to states in sleep that are completely divorced
link |
00:51:46.800
from duration path and outcome
link |
00:51:48.480
in which everything is completely random and untethered
link |
00:51:50.840
in terms of our sensations, perceptions
link |
00:51:52.640
and feelings and so forth.
link |
00:51:54.040
So every 24 hours, we have a phase of our day
link |
00:51:57.500
that is optimal for thinking and focusing
link |
00:52:01.220
and learning and neuroplasticity
link |
00:52:03.400
and doing all sorts of things.
link |
00:52:04.760
We have energy as well.
link |
00:52:06.640
And at another phase of our day, we're tired
link |
00:52:08.800
and we have no ability to focus.
link |
00:52:11.360
We have no ability to engage in duration path
link |
00:52:13.960
outcome types of analysis.
link |
00:52:15.800
And it's interesting that both phases are important
link |
00:52:19.920
for shaping our nervous system in the ways that we want.
link |
00:52:22.600
So if we want to engage in neuroplasticity
link |
00:52:24.560
and we want to get the most out of our nervous system,
link |
00:52:27.260
we each have to master that both the transition
link |
00:52:30.680
between wakefulness and sleep
link |
00:52:32.800
and the transition between sleep and wakefulness.
link |
00:52:35.480
Now, so much has been made of the importance of sleep.
link |
00:52:37.900
And it is critically important for wound healing,
link |
00:52:40.520
for learning, as I just mentioned,
link |
00:52:42.040
for consolidating learning,
link |
00:52:44.000
for all aspects of our immune system.
link |
00:52:47.340
It is the one period of time
link |
00:52:48.480
in which we're not doing these duration path
link |
00:52:50.140
and outcomes types of analyses.
link |
00:52:51.720
And it is critically important to all aspects of our health,
link |
00:52:54.160
including our longevity.
link |
00:52:56.960
Much less has been made, however,
link |
00:52:59.100
of how to get better at sleeping,
link |
00:53:01.800
how to get better at the process
link |
00:53:03.760
that involves falling asleep, staying asleep,
link |
00:53:06.640
and accessing these states of mind and body
link |
00:53:10.060
that involve total paralysis.
link |
00:53:11.720
Most people don't know this,
link |
00:53:12.560
but you're actually paralyzed during much of your sleep
link |
00:53:14.900
so that you can't act out your dreams, presumably.
link |
00:53:17.520
But also where your brain is in a total idle state
link |
00:53:21.800
where it's not controlling anything,
link |
00:53:24.000
it's just left to kind of free run.
link |
00:53:27.200
And there are certain things that we can all do
link |
00:53:29.880
in order to master that transition,
link |
00:53:32.400
in order to get better at sleeping.
link |
00:53:34.360
And it involves much more than just how much we sleep.
link |
00:53:36.680
We're all being told, of course,
link |
00:53:37.920
that we need to sleep more,
link |
00:53:39.400
but there's also the issue of sleep quality,
link |
00:53:41.760
accessing those deep states of non-DPO thinking,
link |
00:53:45.320
accessing the right timing of sleep.
link |
00:53:48.080
Not a lot has been discussed publicly,
link |
00:53:49.800
as far as I'm aware, of when to time your sleep.
link |
00:53:52.560
I think we all can appreciate that sleeping
link |
00:53:55.380
for half an hour throughout the day
link |
00:53:57.840
so that you get a total of eight hours of sleep
link |
00:54:00.960
every 24 hour cycle is probably very different
link |
00:54:04.040
and not optimal compared to a solid block
link |
00:54:06.220
of eight hours of sleep.
link |
00:54:07.340
Although there are people that have tried this.
link |
00:54:08.880
I think it's been written about in various books.
link |
00:54:11.800
Not many people can stick to that schedule.
link |
00:54:14.460
Incidentally, I think it's called the Uberman schedule,
link |
00:54:16.560
not to be confused with the Huberman schedule,
link |
00:54:19.040
because first of all,
link |
00:54:19.860
my schedule doesn't look anything like that.
link |
00:54:21.280
And second of all,
link |
00:54:22.120
I would never attempt such a sleeping regime.
link |
00:54:25.640
The other thing that is really important to understand
link |
00:54:28.840
is that we have not explored as a culture
link |
00:54:32.840
the rhythms that occur in our waking states.
link |
00:54:35.840
So much has been focused on the value of sleep
link |
00:54:38.240
and the importance of sleep, which is great,
link |
00:54:40.440
but I don't think that most people are paying attention
link |
00:54:42.920
to what's happening in their waking states
link |
00:54:44.740
and when their brain is optimized for focus,
link |
00:54:47.520
when their brain is optimized for these DPOs,
link |
00:54:49.880
these duration path outcome types of engagements
link |
00:54:53.120
for learning and for changing,
link |
00:54:55.200
and when their brain is probably better suited
link |
00:54:57.320
for more reflexive thinking and behaviors.
link |
00:54:59.520
And it turns out
link |
00:55:00.840
that there's a vast amount of scientific data
link |
00:55:04.920
which points to the existence
link |
00:55:06.360
of what are called ultradian rhythms.
link |
00:55:08.460
You may have heard of circadian rhythms.
link |
00:55:10.760
Circadian means circa about a day.
link |
00:55:13.640
So it's 24 hour rhythms
link |
00:55:15.120
because the earth spins once every 24 hours.
link |
00:55:18.080
Ultradian rhythms occur throughout the day
link |
00:55:21.960
and they require less time, they're shorter.
link |
00:55:24.640
The most important ultradian rhythm
link |
00:55:26.120
for sake of this discussion is the 90 minute rhythm
link |
00:55:28.640
that we're going through all the time
link |
00:55:31.000
in our ability to attend and focus.
link |
00:55:34.000
And in sleep, our sleep is broken up
link |
00:55:37.400
into 90 minute segments.
link |
00:55:39.500
Early in the night,
link |
00:55:40.340
we have more phase one and phase two lighter sleep
link |
00:55:42.960
and then we go into our deeper phase three
link |
00:55:44.560
and phase four sleep
link |
00:55:45.400
and then we return to phase one, two, three, four.
link |
00:55:47.520
So all night you're going through these ultradian rhythms
link |
00:55:50.180
of stage one, two, three, four, one, two, three, four,
link |
00:55:53.360
it's repeating.
link |
00:55:54.940
Most people perhaps know that, maybe they don't,
link |
00:55:57.720
but when you wake up in the morning,
link |
00:56:00.120
these ultradian rhythms continue.
link |
00:56:02.280
And it turns out that we are optimized
link |
00:56:04.480
for focus and attention within these 90 minute cycles
link |
00:56:08.500
so that at the beginning of one of these 90 minute cycles,
link |
00:56:10.800
maybe you sit down to learn something new
link |
00:56:12.480
or to engage in some new challenging behavior.
link |
00:56:15.720
For the first five or 10 minutes of one of those cycles,
link |
00:56:18.160
it's well known that the brain and the neural circuits
link |
00:56:20.800
and the neuromodulators are not gonna be optimally tuned
link |
00:56:24.840
to whatever it is you're trying to do.
link |
00:56:26.080
But as you drop deeper into that 90 minute cycle,
link |
00:56:28.560
your ability to focus and to engage in this DPO process
link |
00:56:32.240
and to direct neural plasticity and to learn
link |
00:56:35.280
is actually much greater.
link |
00:56:36.700
And then you eventually pop out of that
link |
00:56:39.180
at the end of the 90 minute cycle.
link |
00:56:41.060
So these cycles are occurring in sleep
link |
00:56:43.120
and these cycles are occurring in wakefulness.
link |
00:56:45.300
And all of those are governed by this seesaw
link |
00:56:47.960
of alertness to calmness
link |
00:56:49.320
that we call the autonomic nervous system.
link |
00:56:51.620
So if you want to master and control your nervous system,
link |
00:56:55.340
regardless of what tool you reach to,
link |
00:56:57.400
whether or not it's a pharmacologic tool
link |
00:56:59.040
or whether or not it's a behavioral tool
link |
00:57:00.640
or whether or not it's a brain machine interface tool,
link |
00:57:03.980
it's vitally important to understand
link |
00:57:06.560
that your entire existence
link |
00:57:08.800
is occurring in these 90 minute cycles,
link |
00:57:11.140
whether or not you're asleep or awake.
link |
00:57:13.000
And so you really need to learn
link |
00:57:14.520
how to wedge into those 90 minute cycles.
link |
00:57:17.600
And for instance, it would be completely crazy
link |
00:57:20.880
and counterproductive to try and just learn information
link |
00:57:24.040
while in deep sleep by listening to that information
link |
00:57:26.320
because you're not able to access it.
link |
00:57:28.440
It would be perfectly good, however,
link |
00:57:31.320
to engage in a focus bout of learning each day.
link |
00:57:34.200
And now we know how long
link |
00:57:35.440
that focus bout of learning should be.
link |
00:57:37.120
It should be at least one 90 minute cycle.
link |
00:57:39.360
And the expectation should be that the early phase
link |
00:57:42.120
of that cycle is going to be challenging.
link |
00:57:44.260
It's going to hurt.
link |
00:57:45.100
It's not going to feel natural.
link |
00:57:46.280
It's not going to feel like flow,
link |
00:57:48.180
but that you can learn
link |
00:57:49.900
and the circuits of your brain
link |
00:57:51.280
that are involved in focus and motivation
link |
00:57:53.160
can learn to drop in to a mode of more focus,
link |
00:57:56.780
get more neuroplasticity, in other words,
link |
00:57:59.360
by engaging these ultradian cycles
link |
00:58:02.080
at the appropriate times of day.
link |
00:58:04.320
For instance, some people are very good learners
link |
00:58:06.500
early in the day and not so good in the afternoon.
link |
00:58:09.080
So you can start to explore this process
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00:58:11.840
even without any information
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00:58:13.640
about the underlying neurochemicals
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00:58:15.060
by simply paying attention,
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00:58:16.880
not just to when you go to sleep
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00:58:18.320
and when you wake up each morning,
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00:58:20.320
how deep or how shallow your sleep felt to you subjectively,
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00:58:24.020
but also throughout the day
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00:58:25.320
when your brain tends to be most anxious,
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00:58:28.440
because it turns out that has a correlate
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00:58:30.820
related to perception that we will talk about.
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00:58:34.800
You can ask yourself, when are you most focused?
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00:58:37.180
When are you least anxious?
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00:58:38.320
When do you feel most motivated?
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00:58:40.000
When do you feel least motivated?
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00:58:42.920
By understanding how the different aspects
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00:58:45.640
of your perception, sensation, feeling, thought,
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00:58:47.800
and actions tend to want to be engaged
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00:58:51.040
or not want to be engaged,
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00:58:52.460
you develop a very good window
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00:58:54.920
into what's going to be required
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00:58:56.600
to shift your ability to focus
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00:58:59.560
or shift your ability to engage in creative type thinking
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00:59:03.320
at different times of day, should you choose.
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00:59:05.760
And so that's where we're heading going forward.
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00:59:07.860
It all starts with mastering this seesaw
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00:59:10.660
that is the autonomic nervous system
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00:59:12.440
that at a course level is a transition
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00:59:14.800
between wakefulness and sleep.
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00:59:16.800
But at a finer level, and just as important
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00:59:19.520
are the various cycles,
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00:59:20.560
these ultradian 90 minute cycles
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00:59:22.200
that govern our life all the time,
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00:59:24.200
24 hours a day, every day of our life.
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00:59:26.440
And so we're going to talk about
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00:59:27.540
how you can take control of the autonomic nervous system
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00:59:30.080
so that you can better access neuroplasticity,
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00:59:33.080
better access sleep,
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00:59:34.760
even take advantage of the phase
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00:59:36.680
that is the transition between sleep and waking
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00:59:38.880
to access things like creativity and so forth.
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00:59:42.520
All based on studies that have been published
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00:59:44.880
over the last hundred years,
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00:59:46.020
mainly within the last 10 years
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00:59:47.680
and some that are very, very new
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00:59:49.320
and that point to the use of specific tools
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00:59:51.640
that will allow you to get the most
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00:59:53.400
out of your nervous system.
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00:59:55.120
So today we covered a lot of information.
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00:59:57.640
It was sort of a whirlwind tour
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00:59:59.420
of everything from neurons and synapses
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01:00:01.760
to neuroplasticity in the autonomic nervous system.
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01:00:04.460
We will revisit a lot of these themes going forward.
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01:00:07.220
So if all of that didn't sink in in one pass,
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01:00:10.560
please don't worry.
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01:00:11.440
We will come back to these themes over and over again.
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01:00:14.440
I wanted to equip you with a language
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01:00:16.960
that we're all developing a kind of common base set
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01:00:20.280
of information going forward.
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01:00:22.200
And I hope the information is valuable to you
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01:00:24.200
in your thinking about what is working well for you
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01:00:27.320
and what's working less well
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01:00:29.360
and what's been exceedingly challenging
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01:00:31.000
and what's been easy for you
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01:00:32.300
in terms of your pursuit of particular behaviors
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01:00:34.840
or emotional states,
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01:00:36.300
where your challenges or the challenges of people
link |
01:00:38.280
that you know might reside.
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01:00:40.680
As promised in our welcome video,
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01:00:42.700
the format of the Huberman Lab Podcast
link |
01:00:44.720
is to dive deep into individual topics
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01:00:47.000
for an entire month at a time.
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01:00:49.060
So for the entire month of January,
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01:00:51.000
we're going to explore this incredible state that is sleep
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01:00:55.160
and a related state, which is non-sleep deep rest.
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01:00:58.980
And what they do for things like learning,
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01:01:01.940
resetting our emotional capacity.
link |
01:01:04.080
Everyone's probably familiar with the fact
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01:01:05.480
that when we're sleep deprived,
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01:01:06.480
we're so much less good at dealing with life circumstances.
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01:01:10.960
We're more emotionally labile.
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01:01:12.920
Why is that?
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01:01:13.760
How is that?
link |
01:01:14.740
But most importantly,
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01:01:15.580
we're going to talk about how to get better at sleeping
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01:01:17.520
and then how to access better sleep,
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01:01:19.280
even when your sleep timing or duration is compromised.
link |
01:01:24.240
We're also going to talk about the data
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01:01:26.260
that support this very interesting state
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01:01:29.000
called non-sleep deep rest,
link |
01:01:31.520
where one is neither asleep nor awake,
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01:01:34.140
but it turns out one can recover
link |
01:01:36.160
some of the neuromodulators
link |
01:01:37.760
and more importantly,
link |
01:01:38.600
the processes involved in sensation, perception,
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01:01:41.600
feeling, thought, and action.
link |
01:01:43.020
It's sure to be a very rich discussion back and forth
link |
01:01:46.480
where I'm answering your questions and providing tools.
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01:01:49.420
And I'm certain you're also going to learn
link |
01:01:51.320
a lot of information about neuroscience
link |
01:01:54.280
and what makes up this incredible phase of your life
link |
01:01:57.180
where you think you're not conscious,
link |
01:01:58.640
but you're actually resetting and renewing yourself
link |
01:02:02.240
in order to perform better, feel better, et cetera,
link |
01:02:05.120
in the waking state.
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01:02:06.560
If you want to support the podcast,
link |
01:02:08.060
please click the like button and subscribe on YouTube.
link |
01:02:11.320
Leave us a comment if you have any feedback for us.
link |
01:02:13.920
And on Apple, you can also leave a review
link |
01:02:16.360
and comments for us to improve
link |
01:02:19.020
the podcast experience for you.
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01:02:20.940
Please also check out our sponsors and thank you so much.
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01:02:23.880
We'll see you on the next episode next week.
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01:02:25.920
We'll see you on the next episode.